Robin L. Bailey
University of London
Publications 312
#1Timothy P. W. Jones (Royal Free Hospital)
#2John Hart (Lond: University of London)H-Index: 74
Last.Robin L. Bailey (Lond: University of London)H-Index: 49
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Helminthic and protozoan infections are common, particularly in low- or middle-income countries. Although an association between parasite carriage and markers of poor growth have been shown in some studies, systematic reviews have suggested only a modest impact of clearing carriage. The prevalence of these pathogens and the effect that they have on growth in preschool children has never been investigated in Malawi. One hundred ninety-three children aged 0–72 months were randomly recruited from r...
#1Laura Senyonjo (Lond: University of London)H-Index: 2
#2Agatha AboeH-Index: 3
Last.Karl Blanchet (Lond: University of London)H-Index: 12
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Background In 2009 Ghana began to design a trachoma pre-validation surveillance plan, based on then-current WHO recommendations. The plan aimed to identify active trachoma resurgence and identify and manage trichiasis cases, through both active and passive surveillance approaches. This paper outlines and reviews the adaptations made by Ghana between 2011 and 2016. The assessment will provide a learning opportunity for a number of countries as they progress towards elimination status.
#1Harry Pickering (Lond: University of London)H-Index: 4
#2C. Palmer (Lond: University of London)H-Index: 92
Last.Matthew J. Burton (Lond: University of London)H-Index: 29
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Background Trachoma, a neglected tropical disease, is the leading infectious cause of blindness and visual impairment worldwide. Host responses to ocular chlamydial infection resulting in chronic inflammation and expansion of non-chlamydial bacteria are hypothesised risk factors for development of active trachoma and conjunctival scarring Methods Ocular swabs from trachoma endemic populations in The Gambia were selected from archived samples for 16S sequencing and host conjunctival gene expressi...
#1Ailie Robinson (Lond: University of London)H-Index: 7
#2Julie Bristow (University of Sussex)
Last.Virginia Sarah (The Fred Hollows Foundation)H-Index: 3
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Background The putative vector of trachoma, Musca sorbens, prefers to lay its eggs on human faeces on the ground. This study sought to determine whether M. sorbens females were attracted to volatile odours from human faeces in preference to odours from the faeces of other animals, and to determine whether specific volatile semiochemicals mediate selection of the faeces. Methodology/Principal findings Traps baited with the faeces of humans and local domestic animals were used to catch flies at tw...
#1Athumani M. Ramadhani (Lond: University of London)H-Index: 6
#2Tamsyn Derrick (Lond: University of London)H-Index: 6
Last.Tara Mtuy (Lond: University of London)H-Index: 3
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Background Trachoma is a progressive blinding disease initiated by infection of the conjunctiva with Chlamydia trachomatis. Repeated infections are thought to cause chronic inflammation, which drives scarring, leading to in-turning of the eyelids. The relationship between C. trachomatis, clinical inflammation and scarring development in children is not fully understood due to a paucity of longitudinal studies with infection data at frequent follow-up. Methods and findings This longitudinal cohor...
#1Athumani M. Ramadhani (Lond: University of London)H-Index: 6
#2Tamsyn Derrick (Lond: University of London)H-Index: 6
Last.Robin L. Bailey (Lond: University of London)H-Index: 49
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Background Trachoma, caused by Chlamydia trachomatis, remains the leading infectious cause of blindness worldwide. Persistence and progression of the resulting clinical disease appears to be an immunologically mediated process. Azithromycin, which is distributed at the community level for trachoma control, has immunomodulatory properties. We investigated the impact of one round of oral azithromycin on conjunctival immune responses, C. trachomatis infection and clinical signs three- and six- mont...