Robin L. Bailey
University of London
ImmunologyTrachomaChlamydia trachomatisMedicineBiology
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Publications 307
#1Harry PickeringH-Index: 6
#2Ambahun ChernetH-Index: 1
Last. Zerihun TadesseH-Index: 14
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Background: To eliminate trachoma as a public health problem, the WHO recommends the SAFE strategy. As part of the SAFE strategy in the Amhara Region, Ethiopia, the Trachoma Control Program distributed over 124 million doses of antibiotic between 2007 and 2015. Despite these interventions, trachoma remained hyperendemic in many districts and a considerable level of Chlamydia trachomatis (Ct) infection was evident. Methods: We utilised residual material from Abbott m2000 Ct diagnostic tests to se...
#1Kieran O'BrienH-Index: 22
#2Abdou AmzaH-Index: 9
Last. Catherine E. OldenburgH-Index: 24
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OBJECTIVE: In the present study, we aimed to compare anthropometric indicators as predictors of mortality in a community-based setting. DESIGN: We conducted a population-based longitudinal study nested in a cluster-randomized trial. We assessed weight, height and mid-upper arm circumference (MUAC) on children 12 months after the trial began and used the trial's annual census and monitoring visits to assess mortality over 2 years. SETTING: Niger. PARTICIPANTS: Children aged 6-60 months during the...
#1Colin MacLeod (Lond: University of London)H-Index: 46
#1Colin K. Macleod (Lond: University of London)H-Index: 6
Last. Anthony W. Solomon (Lond: University of London)H-Index: 30
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: Sample sizes in cluster surveys must be greater than those in surveys using simple random sampling to provide similarly precise prevalence estimates, because results from subjects examined in the same cluster cannot be assumed to be independent. Therefore, a crucial aspect of cluster sampling is estimation of the intracluster correlation coefficient (\rho: the degree of relatedness of outcomes in a given cluster, defined as the proportion of total variance accounted for by between-cluster v...
#1Tamsyn DerrickH-Index: 7
Last. Robin L. BaileyH-Index: 51
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Trachoma is initiated during childhood following repeated conjunctival infection with Chlamydia trachomatis, which causes a chronic inflammatory response in some individuals that leads to scarring and in-turning of the eyelids in later life. There is currently no treatment to halt the progression of scarring trachoma due to an incomplete understanding of disease pathogenesis. A cohort study was performed in northern Tanzania in 616 children aged 6-10 at enrolment. Every three months for four yea...
BACKGROUND: Bubaque is the most populous island of the Bijagos archipelago, a group of malaria-endemic islands situated off the coast of Guinea-Bissau, West Africa. Malaria vector control on Bubaque relies almost exclusively on the use of long-lasting insecticidal nets (LLINs). However, there is little information on local vector bionomics and insecticide resistance. METHODS: A survey of mosquito species composition was performed at the onset of the wet season (June/July) and the beginning of th...
#1Catherine E. Oldenburg (UCSF: University of California, San Francisco)H-Index: 24
#2Abdou AmzaH-Index: 9
Last. Diana L. MartinH-Index: 12
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Background Biannual mass azithromycin administration to preschool children reduces all-cause mortality, but the mechanism for the effect is not understood. Azithromycin has activity against malaria parasites, and malaria is a leading cause of child mortality in the Sahel. The effect of biannual versus annual azithromycin distribution for trachoma control on serological response to merozoite surface protein 1 (MSP-119), a surrogate for malaria incidence, was evaluated among children in Niger.
#1Michael Marks (Lond: University of London)H-Index: 18
#2Thomas Sammut (Lond: University of London)
Last. Stephen L. Walker (Lond: University of London)H-Index: 17
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Introduction Skin diseases represent a significant public health problem in most low and middle income settings. Nevertheless, there is a relative paucity of high-quality epidemiological data on the prevalence of these conditions. Materials/Methods We conducted two cross-sectional population-based skin-surveys of children (6 months to 9 years old) in the Bijagos Archipelago of Guinea-Bissau during the dry season (February-March 2018) and the wet season (June-July 2018). Following a period of tra...
1 CitationsSource
#1Maria João Lopes (Lond: University of London)
Last. Michael Marks (UCL: University College London)H-Index: 18
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Background Scabies is highly endemic among impoverished populations and has been recently included in the WHO’s list of neglected tropical diseases (NTDs). Community support and behavioural changes are essential for the success of control interventions. This study aimed to explore beliefs, prevention attitudes and healthcare-seeking behaviours towards scabies in the Bijagos Archipelago of Guinea-Bissau. Methods Data were collected through two methods. Community key informants (community members,...
#1Sarah E. Burr (Lond: University of London)H-Index: 22
#2John Hart (Lond: University of London)H-Index: 77
Last. Khumbo Kalua (UNIMA: University of Malawi)H-Index: 14
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Background Following one to five years of antibiotic mass drug administration (MDA) for the elimination of trachoma as a public health problem, programmes must conduct impact surveys to inform decisions on whether MDA is still needed. These decisions are currently based on the prevalence of trachomatous inflammation—follicular (TF), which, after MDA, correlates poorly with prevalence of ocular Chlamydia trachomatis infection. Methodology/Principal findings Impact surveys in six evaluation units ...
1 CitationsSource
#1Emma M. Harding-Esch (Lond: University of London)H-Index: 17
#2Martin J. Holland (Medical Research Council)H-Index: 42
Last. Robin L. Bailey (Lond: University of London)H-Index: 51
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Background Mass drug administration (MDA) with azithromycin is a cornerstone of the trachoma elimination strategy. Although the global prevalence of active trachoma has declined considerably, prevalence persists or even increases in some communities and districts. To increase understanding of MDA impact, we investigated the prevalence of active trachoma and ocular C. trachomatis prevalence, organism load, and circulating strains at baseline and one-year post-MDA in The Gambia and Senegal.
1 CitationsSource