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Gwo-Shing Chen
Kaohsiung Medical University
PathologyDermatologyImmunologyDiabetes mellitusMedicine
141Publications
25H-index
1,775Citations
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Publications 144
Newest
#1Alice Ya‐Yun Huang (KMU: Kaohsiung Medical University)
#2Chi-Ling Lin (KMU: Kaohsiung Medical University)H-Index: 7
Last. Stephen Chu-Sung HuH-Index: 11
view all 4 authors...
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#1Shu-Mei Huang (KMU: Kaohsiung Medical University)H-Index: 3
#2Ching-Shuang Wu (NSYSU: National Sun Yat-sen University)H-Index: 2
Last. Cheng-Che E. Lan (KMU: Kaohsiung Medical University)H-Index: 21
view all 7 authors...
Abstract Background Macrophages play important roles during wound healing, and delayed healing in diabetics is associated with sustained inflammation. M1 type macrophage is recognized to secrete excessive amount of tumor necrosis factor-alpha (TNF-α) as compared to its M2 counterpart. Objectives We hypothesized that macrophage polarization is different between diabetic and normal rats during skin wounding and has direct impact on keratinocyte function in the context of re-epithelialization. Meth...
1 CitationsSource
#1Stephen Chu-Sung HuH-Index: 11
Last. Hung-Pin Tu (KMU: Kaohsiung Medical University)H-Index: 16
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Source
#1Stephen Chu-Sung HuH-Index: 11
#2Gwo-Shing ChenH-Index: 25
Last. H TuH-Index: 1
view all 3 authors...
1 CitationsSource
#1Shu-Mei Huang (KMU: Kaohsiung Medical University)H-Index: 3
#2Ching-Shuang Wu (KMU: Kaohsiung Medical University)H-Index: 13
Last. Cheng-Che E. Lan (KMU: Kaohsiung Medical University)H-Index: 21
view all 6 authors...
Background Diabetes is an important global health issue due to its increasing prevalence and association with various complications. Impaired wound healing is a serious complication associated with diabetes that frequently results in infection and amputation. Galectin-7 (Gal-7) has been reported to play an important role during skin wound healing. Previously, we had demonstrated that high glucose environment alters physiologic functions of keratinocytes and contributes to impaired wound healing ...
3 CitationsSource
#1Stephen Chu-Sung HuH-Index: 11
#2Gwo-Shing ChenH-Index: 25
Last. Yung-Song LinH-Index: 1
view all 5 authors...
2 CitationsSource
#1Cheng-Che E. LanH-Index: 21
#2Ching-Shuang WuH-Index: 13
Last. Gwo-Shing ChenH-Index: 25
view all 9 authors...
Ultraviolet B (UVB) radiation from the sun may lead to photocarcinogenesis of the skin. Sunscreens were used to protect the skin by reducing UVB irradiance, but sunscreen use did not reduce sunburn episodes. It was shown that UVB-induced erythema depends on surface exposure but not irradiance of UVB. We previously showed that irradiance plays a critical role in UVB-induced cell differentiation. This study investigated the impact of irradiance on UVB-induced photocarcinogenesis. For hairless mice...
10 CitationsSource
#1Stephen Chu-Sung Hu (KMU: Kaohsiung Medical University)H-Index: 11
#2C-L K Ke (KMU: Kaohsiung Medical University)H-Index: 3
Last. S.-T. Cheng (KMU: Kaohsiung Medical University)H-Index: 4
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#1Stephen Chu-Sung HuH-Index: 11
#2Hsin-Su YuH-Index: 32
Last. Cheng-Che E. LanH-Index: 21
view all 6 authors...
Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes
46 CitationsSource
#1Stephen Chu-Sung Hu (KMU: Kaohsiung Medical University)H-Index: 11
#2Feng-Lin Yen (NSYSU: National Sun Yat-sen University)H-Index: 17
Last. Gwo-Shing Chen (KMU: Kaohsiung Medical University)H-Index: 25
view all 6 authors...
Background The association between immunosuppressive medication use and herpes zoster (HZ) in patients with systemic lupus erythematosus (SLE) has not been clearly defined. Objective We evaluated the risk of HZ in patients with SLE treated with different immunosuppressants. Methods A nationwide population-based case-control study was conducted using the Taiwanese National Health Insurance Research Database. Cases (1555 patients with SLE who developed HZ) and controls (3049 age- and sex-matched p...
10 CitationsSource
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