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Tamara Grodzicky
Université de Montréal
20Publications
11H-index
1,637Citations
Publications 20
Newest
Published on Jan 1, 2018in Autoimmunity Reviews 7.72
Marvin J. Fritzler58
Estimated H-index: 58
(U of C: University of Calgary),
Marie Hudson41
Estimated H-index: 41
(McGill University)
+ 29 AuthorsM. Baron7
Estimated H-index: 7
(JGH: Jewish General Hospital)
Abstract We studied the clinical correlations and epitopes of autoantibodies directed to a novel autoantigen, Bicaudal D (BICD2), in systemic sclerosis (SSc) and reviewed its relationship to centromere protein A (CENP-A). 451 SSc sera were tested for anti-BICD2 using a paramagnetic bead immunoassay and then univariate and multivariate logistic regression was used to study the association between anti-BICD2 and demographic and clinical parameters as well as other SSc-related autoantibodies. Epito...
Published on Dec 1, 2016in Rheumatology 5.15
Murray Baron42
Estimated H-index: 42
(McGill University),
Janet E. Pope57
Estimated H-index: 57
(UWO: University of Western Ontario)
+ 21 AuthorsJean-Pierre Mathieu10
Estimated H-index: 10
(Hôpital Maisonneuve-Rosemont)
Published on Jul 1, 2016in Journal of Pain and Symptom Management 3.38
Mélanie Racine11
Estimated H-index: 11
(UWO: University of Western Ontario),
Marie Hudson41
Estimated H-index: 41
(McGill University)
+ 18 AuthorsPeter Docherty10
Estimated H-index: 10
Abstract Context Pain and itch are common symptoms reported by patients with systemic sclerosis (SSc; scleroderma), which can markedly diminish function and health-related quality of life (HRQL). Objectives The aim of this exploratory study was to examine the impact that pain, itch, and the interaction of both have on function (depressive symptoms, overall disability, fatigue, sleep disturbance) and HRQL in patients with SSc. Methods A total of 964 patients from the Canadian Scleroderma Reserch ...
Published on Apr 1, 2015in Arthritis Care and Research 4.53
Hebah Alhajeri1
Estimated H-index: 1
(JGH: Jewish General Hospital),
Marie Hudson41
Estimated H-index: 41
(JGH: Jewish General Hospital)
+ 20 AuthorsPeter Docherty10
Estimated H-index: 10
(Moncton Hospital)
Objective The goal of this study was to determine the sensitivity of the new 2013 classification criteria for systemic sclerosis (SSc; scleroderma) in an independent cohort of SSc subjects and to assess the contribution of individual items of the criteria to the overall sensitivity. Methods SSc subjects from the Canadian Scleroderma Research Group cohort were assessed. Sensitivity was determined in several subgroups of patients. In patients without the criterion of skin thickening proximal to th...
Published on Nov 1, 2014in Medicine 1.87
Yves Troyanov7
Estimated H-index: 7
,
Ira N. Targoff40
Estimated H-index: 40
+ 9 AuthorsMarvin J. Fritzler58
Estimated H-index: 58
Dermatomyositis (DM) is a major clinical subset of autoimmune myositis (AIM). The characteristic DM rash (Gottron papules, heliotrope rash) and perifascicular atrophy at skeletal muscle biopsy are regarded as specific features for this diagnosis. However, new concepts are challenging the current definition of DM. A modified Bohan and Peter classification of AIM was proposed in which the core concept was the inclusion of the diagnostic significance of overlap connective tissue disease features. I...
Published on Aug 1, 2014in Scandinavian Journal of Rheumatology 2.71
L Miller1
Estimated H-index: 1
(UdeM: Université de Montréal),
S Chartrand2
Estimated H-index: 2
(UdeM: Université de Montréal)
+ 7 AuthorsTamara Grodzicky11
Estimated H-index: 11
(UdeM: Université de Montréal)
Objectives: Pulmonary hypertension (PH) causes mortality in systemic sclerosis (SSc). Pulmonary arterial hypertension (PAH) and left heart disease (LHD) are frequent causes of PH. Therefore, we studied PAH and LHD in early PH.Method: A total of 432 French Canadian SSc patients were studied retrospectively. All underwent screening for PH. We analysed clinical, serological, and radiographic data from 26 patients with early PH diagnosed by right heart catheterization (RHC). SSc patients with (n = 2...
Published on Jul 1, 2011in Journal of Cellular Physiology 4.52
Stéphane Chabaud10
Estimated H-index: 10
(Laval University),
Marie-Pier Corriveau2
Estimated H-index: 2
(Laval University)
+ 4 AuthorsVéronique Moulin18
Estimated H-index: 18
(Laval University)
Our hypothesis is that the development of lesional areas of skin in patients with systemic sclerosis (SSc) originates from the selection of profibrotic cell subpopulations within their non-lesional skin areas, due to their greater resistance to apoptosis. Sensitivity to apoptosis of early-stage or late-stage SSc fibroblasts as well as of healthy cells was compared using extrinsic or intrinsic apoptotic pathway-inducers. Subpopulations of non-lesional SSc cells and healthy cells obtained after re...
Published on Mar 1, 2009in The Journal of Pathology 5.94
Marie-Pier Corriveau2
Estimated H-index: 2
,
Ines Boufaied1
Estimated H-index: 1
+ 6 AuthorsVéronique Moulin18
Estimated H-index: 18
(Laval University)
We set out to examine the pathophysiological mechanisms of fibrosis in diffuse systemic sclerosis (SSc) using a tissue engineering approach. Skin fibroblasts were isolated from lesional skin of SSc patients with a disease duration of less than 1 year (early-stage SSc) or more than 10 years (late-stage SSc). Fibroblasts were also isolated from non-lesional skin and compared with normal fibroblasts isolated from healthy adults. Cells were cultured using a tissue engineering method to reconstruct a...
Published on Dec 1, 2008in Arthritis & Rheumatism 9.00
Martial Koenig7
Estimated H-index: 7
(UdeM: Université de Montréal),
Marvin J. Fritzler58
Estimated H-index: 58
(U of C: University of Calgary)
+ 7 AuthorsJean-Luc Senécal31
Estimated H-index: 31
(UdeM: Université de Montréal)
Objective To identify in patients with Raynaud's phenomenon (RP) independent markers that predict progression to definite systemic sclerosis (SSc) and to determine in patients with progression to SSc the type and sequence of microvascular damage and its relationship to SSc-specific autoantibodies. Methods Consecutive patients referred for evaluation of RP who had no definite connective tissue disease were evaluated for microvascular damage by nailfold capillary microscopy (NCM) and for anticentr...
Published on Mar 1, 2008in The FASEB Journal 5.39
Marie-Pier Corriveau2
Estimated H-index: 2
,
Ines Boufaied1
Estimated H-index: 1
+ 4 AuthorsVéronique Moulin18
Estimated H-index: 18
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