Mario P. Colombo
Istituto Superiore di Sanità
Publications 1298
#2B RivaH-Index: 4
Last.Armando A. GenazzaniH-Index: 41
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ABSTRACT STIM and ORAI proteins play a fundamental role in calcium signaling, allowing for calcium influx through the plasma membrane upon depletion of intracellular stores, in a process known as store-operated Ca2+ entry. Point mutations that lead to gain-of-function activity of either STIM1 or ORAI1 are responsible for a cluster of ultra-rare syndromes characterized by motor disturbances and platelet dysfunction. The prevalence of these disorders is at present unknown. In this study, we descri...
#1Elisa MartiniH-Index: 5
#2Paolo KunderfrancoH-Index: 12
Last.Marinos Kallikourdis (Humanitas University)H-Index: 11
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Background: Inflammation is a key component of cardiac disease, with macrophages and T lymphocytes mediating essential roles in the progression to heart failure (HF). Nonetheless, little insight ex...
1 CitationsSource
The presence of a growing tumor establishes a chronic state of inflammation that acts locally and systemically. Bone marrow responds to stress signals by expanding myeloid cells endowed with immunosuppressive functions, further fostering tumor growth and dissemination. How early in transformation the crosstalk with the bone marrow begins and becomes detectable in blood is unknown. Here, gene expression profiling of the bone marrow along disease progression in a spontaneous model of mammary carci...
#1Mario P. ColomboH-Index: 108
#2Carlo La VecchiaH-Index: 123
Last.Valérie ParadisH-Index: 46
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Summary A variety of chemicals have been linked to occupational liver diseases, including several solvents and mixtures thereof, pesticides, and metals. Workplace exposures have been associated with virtually the entire spectrum of acute and chronic liver diseases. However, their prevalence is inadequately quantified and their epidemiology limited. Occupational liver diseases may result from high accidental or from prolonged lower level exposures. Whereas the former is uncommon and easily recogn...
#1Alessandro Loglio (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 6
#2Massimo Iavarone (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 24
Last.Pietro Lampertico (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 41
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#1G. Lo RussoH-Index: 1
#2D. SignorelliH-Index: 2
Last.Marina Chiara GarassinoH-Index: 27
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#1Francisco Averhoff (CDC: Centers for Disease Control and Prevention)H-Index: 19
#2Jeffrey V. Lazarus (University of Barcelona)H-Index: 25
Last.Muazzam Nasrullah (CDC: Centers for Disease Control and Prevention)H-Index: 8
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#1Giulia GalliH-Index: 66
#2Roberto FerraraH-Index: 11
Last.Claudia ProtoH-Index: 8
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