Baiyong Shen
Shanghai Jiao Tong University
Publications 114
#1Xin Xie (CPU: China Pharmaceutical University)H-Index: 1
#2Lingman Ma (CPU: China Pharmaceutical University)H-Index: 2
Last.Changlin Zhou (CPU: China Pharmaceutical University)H-Index: 12
view all 8 authors...
Abstract A polysaccharide isolated from Strongylocentrotus nudus eggs (SEP) reportedly displays immune activity in vivo. Here, its effect and underlying mechanism in the treatment of pancreatic cancer were investigated. SEP obviously inhibited pancreatic cancer growth by activating NK cells in vitro/vivo via TLR4/MAPKs/NF-κB signaling pathway, The tumor inhibitory rate achieved to 44.5% and 50.8% at a dose of 40 mg/kg in Bxpc-3 and SW1990 nude mice, respectively. Moreover, SEP obviously augmente...
#1Shi Chen (Fujian Medical University)H-Index: 6
#2Jiaqiang Zhang (SJTU: Shanghai Jiao Tong University)H-Index: 6
Last.Hui-Xing Chen (Fujian Medical University)H-Index: 2
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Increasing incidence and mortality rates of pancreatic cancer (PC) highlight an urgent need for novel and efficient drugs. Retention in endoplasmic reticulum 1 (RER1) is an important retention factor in the endoplasmic reticulum (ER). However, it remains elusive whether RER1 is involved in the retention of disease-related proteins. We analyzed the expression level of RER1 in PC and adjacent tissues, and also employed Kaplan–Meier’s analysis to identify the correlation between RER1 expression and...
#1Yusheng Shi (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Jiabin Jin (SJTU: Shanghai Jiao Tong University)H-Index: 7
Last.Chenghong Peng (SJTU: Shanghai Jiao Tong University)H-Index: 20
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Abstract Background The aim of this study was to determine the feasibility, safety, and rate of postoperative complications after robot-assisted middle pancreatectomy compared with open middle pancreatectomy. Methods This retrospective study was conducted in Shanghai Ruijin Hospital, China, involving 170 patients who underwent robot-assisted middle pancreatectomy or open middle pancreatectomy from December 2010 to December 2017. Patients were in 1 of 2 groups: robot-assisted middle pancreatectom...
#1Jiabin Jin (SJTU: Shanghai Jiao Tong University)H-Index: 7
#2Kai Qin (SJTU: Shanghai Jiao Tong University)H-Index: 2
Last.Chenghong Peng (SJTU: Shanghai Jiao Tong University)H-Index: 20
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Summary Background Robotic surgery is the most advanced minimally invasive technique for the treatment of complicated solid pseudopapillary tumors (SPT). The aim of this study is to evaluate feasibility of robotic surgery for the treatment of SPTs in the pancreatic head. Methods A retrospective analysis of the clinical data of 83 SPTs in pancreatic head was conducted. Clinical characteristics were extracted and propensity score matching (PSM) was used to compare and evaluate mid-term outcomes of...
#1Shi Chen (Fujian Medical University)H-Index: 6
#2Jiangzhi Chen (Fujian Medical University)H-Index: 2
Last.Yan-LingChen (Fujian Medical University)H-Index: 9
view all 11 authors...
Abstract Pancreatic cancer (PC) represents a relatively rare but severe malignancy worldwide. Accumulated studies have emphasized the potential of long noncoding RNA (lncRNA) as therapeutic strategies for several human cancers. Thus, we aimed to investigate whether a novel non-coding RNA regulatory circuitry involved in PC. Aberrantly expressed lncRNAs and mRNAs were screened out of microarray database. Following the determination of RNA expression, PANC-1 and BxPC-3 PC cells were adopted, after...