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Stephen J. Smith
Murdoch University
5Publications
Publications 5
Newest
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
#2Stephen J. Smith (Murdoch University)
Last.Peter D. Drummond (Murdoch University)H-Index: 45
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Background:As a stand-alone intervention, saffron has efficacy for the treatment of mild-to-moderate depression. However, research as an adjunct agent is limited.Aims:The effects of saffron as an a...
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
#2Peter D. Drummond (Murdoch University)H-Index: 45
Last.Stephen J. Smith (Murdoch University)
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Ashwagandha (Withania somnifera) is a herb commonly used in Ayurvedic medicine to promote youthful vigor, enhance muscle strength and endurance, and improve overall health. In this 16-week, randomized, double-blind, placebo-controlled, crossover study, its effects on fatigue, vigor, and steroid hormones in aging men were investigated. Overweight men aged 40–70 years, with mild fatigue, were given a placebo or an ashwagandha extract (Shoden beads, delivering 21 mg of withanolide glycosides a day)...
#1Adrian L. LoprestiH-Index: 10
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Background: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic effects on adults with self-reported high stress and to examine potential mechanisms associated with its therapeutic effects. Methods: In this 60-day, randomized, double-blind, placebo-controlled study the stress-relieving and pharmacological activity of an ashwagandha extract was investigated in stressed, healthy adu...
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
Last.Stephen J. Smith (SCU: Southern Cross University)
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Background To evaluate the efficacy and tolerability of a poly-herbal formulation, Herbagut, for the treatment of gastrointestinal symptoms and its effect on quality of life parameters in patients presenting with self-reported, unsatisfactory bowel habits.
#1Briony Nicholls (University of Oxford)H-Index: 3
#2Jane Mellanby (University of Oxford)H-Index: 20
Last.Stephen SmithH-Index: 1
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The effects of chlordiazepoxide and the inverse agonist, Ro 15-4513, were compared on the exploratory response of rats to a novel object introduced into a familiar environment containing seven familiar objects. While chlordiazepoxide (5 mg/kg) increased the novelty response, Ro 15-4513 reduced the response in a dose-dependent manner (0.5-5.0 mg/kg). This action was specific to novelty since the response to the familiar objects was unaffected. Both drugs produced some reduction in ambulation. The...
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