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Teresa E. Fowler
Georgia Institute of Technology
5Publications
2H-index
29Citations
Publications 5
Newest
Ryan Fredric Bloomquist5
Estimated H-index: 5
,
Teresa E. Fowler2
Estimated H-index: 2
+ 5 AuthorsJ. Todd Streelman27
Estimated H-index: 27
In Lake Malawi cichlids, each tooth is replaced in one-for-one fashion every ∼20 to 50 d, and taste buds (TBs) are continuously renewed as in mammals. These structures are colocalized in the fish mouth and throat, from the point of initiation through adulthood. Here, we found that replacement teeth (RT) share a continuous band of epithelium with adjacent TBs and that both organs coexpress stem cell factors in subsets of label-retaining cells. We used RNA-seq to characterize transcriptomes of RT ...
Published on Dec 1, 2018in Nature Communications11.88
Zhengwen An4
Estimated H-index: 4
('KCL': King's College London),
Maja Sabalić2
Estimated H-index: 2
('KCL': King's College London)
+ 3 AuthorsPaul T. Sharpe62
Estimated H-index: 62
('KCL': King's College London)
The extent to which heterogeneity within mesenchymal stem cell (MSC) populations is related to function is not understood. Using the archetypal MSC in vitro surface marker, CD90/Thy1, here we show that 30% of the MSCs in the continuously growing mouse incisor express CD90/Thy1 and these cells give rise to 30% of the differentiated cell progeny during postnatal development. In adulthood, when growth rate homeostasis is established, the CD90/Thy1+ MSCs decrease dramatically in number. When adult i...
Published on Dec 1, 2017in BMC Developmental Biology2.37
Ryan Fredric Bloomquist5
Estimated H-index: 5
(Georgia Regents University),
Teresa E. Fowler2
Estimated H-index: 2
(Georgia Institute of Technology)
+ 2 AuthorsJ. T. Streelman1
Estimated H-index: 1
(Georgia Institute of Technology)
Abstract Background Lake Malawi cichlids represent one of a growing number of vertebrate models used to uncover the genetic and developmental basis of trait diversity. Rapid evolutionary radiation has resulted in species that share similar genomes but differ markedly in phenotypes including brains and behavior, nuptial coloration and the craniofacial skeleton. Research has begun to identify the genes, as well as the molecular and developmental pathways that underlie trait divergence. Results We ...
Ryan Fredric Bloomquist5
Estimated H-index: 5
(Georgia Regents University),
Nicholas F. Parnell5
Estimated H-index: 5
(Georgia Institute of Technology)
+ 4 AuthorsJ. Todd Streelman27
Estimated H-index: 27
(Georgia Institute of Technology)
Teeth and taste buds are iteratively patterned structures that line the oro-pharynx of vertebrates. Biologists do not fully understand how teeth and taste buds develop from undifferentiated epithelium or how variation in organ density is regulated. These organs are typically studied independently because of their separate anatomical location in mammals: teeth on the jaw margin and taste buds on the tongue. However, in many aquatic animals like bony fishes, teeth and taste buds are colocalized on...
Published on Jan 1, 2015in Current Topics in Developmental Biology
J. Todd Streelman27
Estimated H-index: 27
(Georgia Institute of Technology),
Ryan Fredric Bloomquist5
Estimated H-index: 5
(Georgia Institute of Technology),
Teresa E. Fowler2
Estimated H-index: 2
(Georgia Institute of Technology)
In many aquatic vertebrates, including bony and cartilaginous fishes, teeth and taste buds colocalize on jaw elements. In these animals, taste buds are renewed continuously throughout life, whereas teeth undergo cycled whole-organ replacement by various means. Recently, studies of cichlid fishes have yielded new insights into the development and regeneration of these dental and sensory oral organs. Tooth and taste bud densities covary positively across species with different feeding strategies, ...
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