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Hongbing Lu
Fourth Military Medical University
Imaging phantomIterative reconstructionComputer visionMathematicsComputer science
206Publications
23H-index
2,535Citations
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Publications 176
Newest
#1Huanjun Wang (SYSU: Sun Yat-sen University)H-Index: 6
#2Xiaopan Xu (Fourth Military Medical University)H-Index: 5
Last. Yan Guo (SYSU: Sun Yat-sen University)H-Index: 4
view all 11 authors...
OBJECTIVES: To develop a multisequence MRI-based radiomics signature for the preoperative prediction of the muscle-invasive status of bladder cancer (BCa). METHODS: This retrospective study involved 106 eligible patients from two independent clinical centers. All patients underwent a preoperative 3.0 T MRI scan with T2-weighted image (T2WI) and multi-b-value diffusion-weighted image (DWI) sequences. In total, 1404 radiomics features were extracted from the largest region of the reported tumor lo...
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#2Xiaopan XuH-Index: 5
Last. Baojuan LiH-Index: 5
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Introduction: Developing a machine learning-based approach which could provide quantitative identification of major depression (MDD) is essential for the diagnosis and intervention of this disorder. However, the performances of traditional algorithms using static functional connectivity (SFC) measures were unsatisfactory. In the present work, we exploit the hidden information embedded in dynamic functional connectivity (DFC) and developed an accurate and objective image-based diagnosis system fo...
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#2Marc PomeroyH-Index: 1
Last. Zhengrong LiangH-Index: 26
view all 6 authors...
In this article, we introduce a deformation independent model to solve the shape and posture changing issue for polyp characterization in computer-aided diagnosis (CADx) via CT colonography. After volumetric data parameterization in a four-dimensional space, the first fundamental form (FFF) is employed to construct the polyp model which contains several excellent properties such as locality, symmetry, orientation robustness, shift and isometric invariance. In consideration of the scaling effects...
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#1Wenli Zhang (Fourth Military Medical University)
#1Wenli Zhang (Fourth Military Medical University)H-Index: 3
Last. Hongbing Lu (Fourth Military Medical University)H-Index: 23
view all 8 authors...
PURPOSE: As a novel imaging modality, x-ray fluorescence computed tomography (XFCT) can provide distribution and concentration information of contrast agents containing high atomic number elements, such as iodine, gadolinium, barium, gold, and platinum. Since XFCT has a better sensitivity and detection limit of high-Z elements compared with traditional and spectral CT, it becomes a powerful quantitative imaging tool for biological studies. The main problem of current XFCT imaging is its low emis...
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#1Xing TangH-Index: 1
#1Xing Tang (Fourth Military Medical University)H-Index: 3
Last. Hongbing LuH-Index: 23
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Background Non-invasive discrimination between lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) subtypes of non-small-cell lung cancer (NSCLC) could be very beneficial to the patients unfit for the invasive diagnostic procedures. The aim of this study was to investigate the feasibility of utilizing the multimodal magnetic resonance imaging (MRI) radiomics and clinical features in classifying NSCLC. This retrospective study involved 148 eligible patients with postoperative patho...
1 CitationsSource
#1Peng Gao (Fourth Military Medical University)H-Index: 4
#2Junyan Rong (Fourth Military Medical University)H-Index: 4
Last. Hongbing Lu (Fourth Military Medical University)H-Index: 23
view all 7 authors...
Significance: As a promising hybrid imaging technique with x-ray excitable nanophosphors, cone-beam x-ray luminescence computed tomography (CB-XLCT) has been proposed for in-depth biological imaging applications. In situations in which the full rotation of the imaging object (or x-ray source) is inapplicable, the x-ray excitation is limited by geometry, or a lower x-ray excitation dose is mandatory, limited view CB-XLCT reconstruction would be essential. However, this will result in severe ill-p...
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#1Weiguo Cao (SUNY: State University of New York System)
#2Zhengrong Jerome Liang (SUNY: State University of New York System)
Last. Hongbing LuH-Index: 23
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Polyp classification is a feature selection and clustering process. Picking the most effective features from multiple polyp descriptors without redundant information is a great challenge in this procedure. We propose a multilayer feature selection method to construct an optimized descriptor for polyp classification with a feature-grouping strategy in a hierarchical framework. First, the proposed method makes good use of image metrics, such as intensity, gradient, and curvature, to divide their c...
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#1Xiaopan Xu (Fourth Military Medical University)H-Index: 5
#2Huanjun Wang (SYSU: Sun Yat-sen University)H-Index: 6
Last. Hongbing Lu (Fourth Military Medical University)H-Index: 23
view all 12 authors...
1 CitationsSource
#1Wenlei LiuH-Index: 3
#2Peng GaoH-Index: 4
Last. Hongbing LuH-Index: 23
view all 7 authors...
Although Low-dose computed tomography (LDCT) is the most effective way for early lung cancer screening, it’s still a challenge to further reduce radiation dose on the premise of ensuring image quality. Penalized weighted least-squares (PWLS) image reconstruction with nonlocal means (NLM) prior has shown excellent performance to improve the image quality for LDCT, especially when the nonlocal weights are calculated from previous full-dose CT (FDCT) image. However, the previous FDCT image of the s...
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#1Xiaopan Xu (Fourth Military Medical University)H-Index: 5
#2Peng Du (Fourth Military Medical University)H-Index: 1
Last. Hongbing Lu (Fourth Military Medical University)H-Index: 23
view all 6 authors...
In this study, a convex global optimization-based continuous max-flow (CGO-CMF) algorithm was proposed for the segmentation of bladder inner and outer walls on T2-weighted MR images (T2WI). Experimental results using 12 datasets of 3.0 T bladder T2WI datasets acquired from both volunteers and the patients with bladder cancer demonstrate a favorable performance and efficiency of the proposed approach for bladder segmentation, with the Dice similarity coefficient (DSC) of 89.8%, and an average tim...
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