Daniel Müller
Leibniz Association
Force spectroscopyMembrane proteinChemistryCrystallographyBiology
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Publications 858
#1Victoria S. Marshe (U of T: University of Toronto)H-Index: 8
#2Farhana Islam (U of T: University of Toronto)
Last. Daniel MüllerH-Index: 93
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Abstract Background MicroRNAs (miRNAs) are small 22 nucleotides long, non-coding RNAs that are potential biomarkers for antidepressant treatment response. We aimed to replicate previous associations of miRNAs with antidepressant treatment response in a sample of older adults diagnosed with late-life depression. Methods Our sample included 184 older adults diagnosed with moderately severe depression that received open-label venlafaxine (up to 300 mg/day) for approximately 12 weeks. We quantified ...
#1Eliette Restrepo (HSG: University of St. Gallen)H-Index: 6
#2Amund N. Løvik (HSG: University of St. Gallen)H-Index: 9
Last. Daniel Müller (NTNU: Norwegian University of Science and Technology)H-Index: 93
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Abstract Car electronics form an extensive yet untapped source for secondary critical raw materials. To seize their recycling potentials it is imperative to understand how the number and volumes of car electric and electronic (EE) devices are affected by trends in: i) car typology, ii) penetration and integration of automobile electronic control systems (AECS), and iii) unit mass of EE devices. We used a layered dynamic material flow analysis (MFA) incorporating comprehensive data series to anal...
#1Stefanie Hassel (Centre for Mental Health)H-Index: 18
#2Gulshan B. Sharma (U of C: University of Calgary)H-Index: 5
Last. Glenda MacQueen (Centre for Mental Health)H-Index: 57
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Task-based functional neuroimaging methods are increasingly being used to identify biomarkers of treatment response in psychiatric disorders. To facilitate meaningful interpretation of neural correlates of tasks and their potential changes with treatment over time, understanding the reliability of the blood-oxygen-level dependent (BOLD) signal of such tasks is essential. We assessed test-retest reliability of an emotional conflict task in healthy participants collected as part of the Canadian Bi...
#1Andrey Dara (Humboldt University of Berlin)H-Index: 2
#2Matthias Baumann (Humboldt University of Berlin)H-Index: 19
Last. Tobias Kuemmerle (Humboldt University of Berlin)H-Index: 52
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Abstract Temperate grasslands are globally widespread, play an important role as carbon storage, and harbor unique biodiversity. Livestock grazing is the most widespread land use in temperate grasslands, and understanding the impact of grazing on grassland ecosystems is therefore important. However, monitoring grazing pressure and how it changes is hampered by a lack of adequate tools. The Eurasian steppe belt, extending from Eastern Europe to China has experienced marked changes in grazing pres...
Pore-forming toxins (PFTs) are a diverse class of membrane-active proteins employed primarily by bacteria for unregulated perforation of lipid membranes (1). Based on molecular dynamics (MD) simulations (2), electron cryo-microscopy (cryoEM) structures (3), and atomic force microscopy (AFM) experiments (4), we recently identified two distinct pathways for lipid efflux from large pores (diameter >30 nm) formed by the β-PFT pneumolysin (PLY). Lipids leave the PLY ring laterally upon slow membrane ...
PURPOSES/BACKGROUND: Antidepressants (ADs) play a valuable role in treating the depressive episodes of bipolar disorder. However, 14% of these individuals taking ADs experience AD-associated mania (AAM) within a few weeks of starting treatment. Numerous studies have suggested potential clinical and genetic risk factors. We aimed to conduct a comprehensive systematic review and meta-analysis that integrates the past literature with the recent studies and identifies important predictors for AAM. M...
#1Gésine L. Alders (McMaster University)
#2Andrew D. Davis (McMaster University)H-Index: 3
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Abstract Background Identifying objective biomarkers can assist in predicting remission/non-remission to treatment, improving remission rates, and reducing illness burden in major depressive disorder (MDD). Methods Sixteen MDD 8-week remitters (MDD-8), twelve 16-week remitters (MDD-16), 14 non-remitters (MDD-NR) and 30 healthy comparison participants (HC) completed a functional magnetic resonance imaging emotional conflict task at baseline, prior to treatment with escitalopram, and 8 weeks after...
#1Abdullah Al Maruf (Centre for Mental Health)
#1Abdullah Al MarufH-Index: 8
Last. Chad A. BousmanH-Index: 22
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Objective:To identify and assess pharmacogenetic testing options relevant to psychiatry in Canada.Method:Searches of published literature, websites, and Standard Council of Canada’s Laboratory Dire...
#1Pawel R. LaskowskiH-Index: 1
#2Kristyna PluhackovaH-Index: 13
Last. Daniel MüllerH-Index: 93
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