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Genjiro Kimura
Nagoya City University
367Publications
43H-index
8,498Citations
Publications 367
Newest
#1Kazuo KitagawaH-Index: 47
#2Yasumasa YamamotoH-Index: 12
Last.Kazuyuki ShimadaH-Index: 64
view all 24 authors...
Importance The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated that a systolic blood pressure (BP) target less than 120 mm Hg was superior to less than 140 mm Hg for preventing vascular events. This trial excluded patients with prior stroke; therefore, the ideal BP target for secondary stroke prevention remains unknown. Objective To assess whether intensive BP control would achieve fewer recurrent strokes vs standard BP control. Design, Setting, and Participants Randomized clini...
3 CitationsSource
#1Genjiro KimuraH-Index: 43
#2Nobutaka InoueH-Index: 1
Last.Masanori MunakataH-Index: 28
view all 7 authors...
It has been reported that cardiovascular events often occur on Monday morning, especially in the young working population. Because hypertension is a major cardiovascular risk, we examined whether blood pressure was elevated on Monday, especially in the morning during work. However, there were no weekly rhythms in blood pressure itself. Instead, we found significant interactions between the double product (systolic blood pressure × heart rate) and weekly (high on Monday) and circadian (high in th...
2 CitationsSource
#1Genjiro KimuraH-Index: 43
#2Masato Kasahara (Kyoto University)H-Index: 19
Last.Kazuwa Nakao (Kyoto University)H-Index: 117
view all 10 authors...
Background Dyslipidemia is a risk factor for the progression of chronic kidney disease (CKD). While conventional lipid lowering therapy provides a benefit to CKD management, the effect of statins on eGFR remains unclear.
10 CitationsSource
Source
#1Tomomi HashimotoH-Index: 2
#2Hiroyuki TakaseH-Index: 13
Last.Yasuaki Dohi (Nagoya City University)H-Index: 25
view all 8 authors...
Abstract The close association between dietary salt and hypertension is well established. However, previous studies generally assessed salt intake without adjustment for body weight. Herein, we investigated the significance of body weight–adjusted salt intake in the general population. The present cross-sectional study included 7629 participants from our yearly physical checkup program, and their salt intake was assessed using a spot urine test to estimate 24-hour urinary salt excretion. Total s...
2 CitationsSource
Primarily the sodium-glucose cotransporter 2 (SGLT2) inhibitors suppress the cotransport of glucose and sodium from the tubular lumen of proximal tubules to the blood and enhance the glucose excretion into urine. Therefore, glucose and caloric balances become negative, making the blood glucose level as well as insulin secretion both reduced. On the other hand, the proximal tubular fluid, constituting with low chloride concentration because of SGLT2 inhibition, is transferred to the loop of Henle...
22 CitationsSource
Primarily, the sodium-glucose cotransporter 2 (SGLT2) inhibitors suppress the cotransport of glucose and sodium from the tubular lumen of the proximal tubules to the blood, and excrete glucose into the urine. Therefore, glucose and caloric balances become negative, reducing both the blood glucose level and insulin secretion. On the other hand, the proximal tubular fluid, constituted with low chloride concentration because of SGLT2 inhibition, is transferred to the loop of Henle. Under low chlori...
26 CitationsSource
#1Hiroyuki TakaseH-Index: 13
#2Tomonori Sugiura (Nagoya City University)H-Index: 14
Last.Yasuaki Dohi (Nagoya City University)H-Index: 25
view all 5 authors...
Background Although there is a close relationship between dietary sodium and hypertension, the concept that persons with relatively high dietary sodium are at increased risk of developing hypertension compared with those with relatively low dietary sodium has not been studied intensively in a cohort. Methods and Results We conducted an observational study to investigate whether dietary sodium intake predicts future blood pressure and the onset of hypertension in the general population. Individua...
25 CitationsSource
#1Satoru TanakaH-Index: 8
#2Tomonori SugiuraH-Index: 14
Last.Nobuyuki OhteH-Index: 29
view all 6 authors...
Central blood pressure may be more closely associated with cardiovascular events than peripheral blood pressure. The aim of the present study was to investigate central blood pressure responses to exercise. Apparently healthy 18 subjects were enrolled in the study (38 ± 6 years) and changes in central and brachial blood pressure were recorded in response to ergometer and hand-grip exercises. Central blood pressure was estimated using an automated device (Omron HEM-9000AI). Systolic brachial bloo...
9 CitationsSource
#1Shunsuke MuraiH-Index: 4
#2Satoru TanakaH-Index: 8
Last.Nobuyuki OhteH-Index: 29
view all 5 authors...
The prevalence, characteristics, and clinical significance of abnormal albuminuria in patients with hypertension
8 CitationsSource
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