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Melissa J. Green
University of New South Wales
PsychiatryDevelopmental psychologyPsychologyBipolar disorderSchizophrenia
188Publications
38H-index
4,295Citations
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Publications 205
Newest
#1Katrina L. Grasby (QIMR: QIMR Berghofer Medical Research Institute)H-Index: 7
#2Neda Jahanshad (SC: University of Southern California)H-Index: 42
Last. Mary Agnes B. McMahon (SC: University of Southern California)
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INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area and thickness are associated with neurological, psychological, and behavioral traits and can be measured in vivo by magnetic resonance imaging (MRI). Studies in model organisms have identified genes that influence cortical structure, but little is known about common genetic variants that affect human cortical structure. RATIONALE To identify genetic variants associated with hu...
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#1Stacy Tzoumakis (Griffith University)H-Index: 9
#2Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
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#1Kristin R. Laurens (UNSW: University of New South Wales)H-Index: 33
#2Fahkrul Islam (UNSW: University of New South Wales)
Last. Vaughan J. Carr (UNSW: University of New South Wales)H-Index: 59
view all 11 authors...
Abstract Background Maltreated children are at risk of poor educational outcomes, but also experience greater individual, family, and neighbourhood adversities that may obscure an understanding of relationships between child protection involvement and educational attainment. Objective To examine associations between child protection involvement and 3rd- and 5th-grade reading and numeracy attainment, while controlling multiple other adversities. Participants and Setting Participants were 56,860 A...
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#1Lo Le (UNSW: University of New South Wales)
#2Kaur R (UNSW: University of New South Wales)
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
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Abstract A meta-analysis was conducted to estimate schizophrenia incidence in first-degree relatives (FDRs) of probands diagnosed with schizophrenia. The aim was to inform future schizophrenia research and improve accuracy of risk communication to patients. Schizophrenia risk in FDRs with 1 or 2 probands with schizophrenia was investigated by conducting a systematic review of cohort and case-control studies with the following criteria: published between 1977 and 2018; report odds ratios (OR), re...
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#1Patrycja J. Piotrowska (NeuRA: Neuroscience Research Australia)
#2Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
Adult psychosocial difficulties, including psychiatric disorders, are often preceded by childhood psychosocial vulnerabilities, presenting critical windows of opportunity for preventative intervention. The present study aimed to identify longitudinal patterns (representing transitions between profiles) of childhood socio-emotional and cognitive vulnerability in the general population from early to middle childhood, in relation to key risk factors (e.g. parental mental illness and offending). Dat...
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Abstract Background : Cognitive heterogeneity in schizophrenia spectrum disorders (SSD) and bipolar disorder (BD) has been explored using clustering analyses. However, the resulting subgroups have not been cognitively validated beyond measures used as clustering variables themselves. We compared the emergent cross-diagnostic subgroups of SSD and BD patients on measures used to classify them, and also across a range of alternative cognitive measures assessing some of the same constructs. Method :...
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#1Mark Pinese (UNSW: University of New South Wales)H-Index: 23
#2Paul Lacaze (Monash University)H-Index: 5
Last. Dmitry Degrave (Garvan Institute of Medical Research)
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Population health research is increasingly focused on the genetic determinants of healthy ageing, but there is no public resource of whole genome sequences and phenotype data from healthy elderly individuals. Here we describe the first release of the Medical Genome Reference Bank (MGRB), comprising whole genome sequence and phenotype of 2570 elderly Australians depleted for cancer, cardiovascular disease, and dementia. We analyse the MGRB for single-nucleotide, indel and structural variation in ...
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#1William R. Reay (University of Newcastle)H-Index: 1
#2Joshua Atkins (University of Newcastle)H-Index: 3
Last. Murray J. Cairns (University of Newcastle)H-Index: 35
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Individuals with complex disorders typically have a heritable burden of common variation that can be expressed as a polygenic risk score (PRS). While PRS has some predictive utility, it lacks the molecular specificity to be directly informative for clinical interventions. We therefore sought to develop a framework to quantify an individual’s common variant enrichment in clinically actionable systems responsive to existing drugs. This was achieved with a metric designated the pharmagenic enrichme...
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#1Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
#2Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
Last. Kimberlie Dean (UNSW: University of New South Wales)H-Index: 25
view all 7 authors...
Contact with the police, as the first contact with the criminal justice system for young people and children, may signify individuals who are vulnerable to later adverse social and health outcomes....
1 CitationsSource
#1Amanda L. Neil (UTAS: University of Tasmania)H-Index: 14
#2Fakhrul Islam (UNSW: University of New South Wales)H-Index: 40
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
Abstract Background Longitudinal data on health costs associated with physical and mental conditions are not available for children reported to child protection services. Objective To estimate the costs of hospitalization for physical and mental health conditions by child protection status, including out-of-home-care (OOHC) placement, from birth until 13-years, and to assess the excess costs associated with child protection contact over this period. Participants and setting Australian population...
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