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Marjorie Bastien
Laval University
26Publications
7H-index
602Citations
Publications 26
Newest
#1Marjorie Bastien (Laval University)H-Index: 7
#2Paul Poirier (Laval University)H-Index: 55
Last.Marie-Ève Piché (Laval University)H-Index: 15
view all 8 authors...
Targeting metabolic determinants of exercise performance with pharmacological agents that would mimic/potentiate the effects of exercise represents an attractive clinical alternative to counterbala...
1 CitationsSource
#1Audrey Auclair (Laval University)H-Index: 6
#2Laurent Biertho (Laval University)H-Index: 14
Last.Paul Poirier (Laval University)H-Index: 55
view all 17 authors...
Background Obesity-associated systemic hypertension (HTN) and obstructive sleep apnea (OSA) have multiple pathophysiological pathways including ectopic fat deposition, inflammation, altered adipokine profile, and increased sympathetic nervous activity. We characterized these potential mechanisms in severely obese patients with or without HTN and OSA. We also compared changes of these mechanisms at 12 months following biliopancreatic diversion with duodenal switch (BPD-DS) surgery according to HT...
6 CitationsSource
#1David H. St-Pierre (UQAM: Université du Québec à Montréal)H-Index: 18
#2Julie Martin (Laval University)H-Index: 9
Last.Paul Poirier (Laval University)H-Index: 55
view all 13 authors...
Abstract Context Nesfatin-1 is a neuroendocrine peptide with potent anorexigenic activity in rodents. The potential role of nesfatin-1 on the regulation of energy balance, metabolic functions and inflammation is currently debated in obese humans. In the present study, nesfatin-1 fluctuations and their associations with metabolic factors were investigated in severely obese patients who underwent biliopancreatic diversion with duodenal switch (BPD/DS) and severely obese controls (SOC). Basic proce...
5 CitationsSource
#1Audrey AuclairH-Index: 6
#2Marie-Ève PichéH-Index: 15
Last.Paul PoirierH-Index: 55
view all 12 authors...
Introduction: Severe obesity is characterized by dysfunctional adipose tissue. Bariatric surgery induces significant and sustained weight loss and comorbidities resolution. Few studies assessed changes of adipose tissue quantity and quality in regards with comorbidities resolution. Objectives: 1) To quantify and qualify visceral adipose tissue (VAT) vs. some comorbidities: obstructive sleep apnea (OSA), dyslipidemia (DLP), systemic hypertension (HTN) and type 2 diabetes (T2D) in severely obese p...
#1Audrey AuclairH-Index: 6
#2Marie-Ève PichéH-Index: 15
Last.Paul PoirierH-Index: 55
view all 13 authors...
Source
#1Audrey Auclair (Laval University)H-Index: 6
#2Julie Martin (Laval University)H-Index: 9
Last.Paul Poirier (Laval University)H-Index: 55
view all 12 authors...
Background Severe obesity is often characterized by ectopic fat deposition, which is related to development of type 2 diabetes (T2D). Thus, resolution of T2D may not be linearly associated with weight loss. The importance of ectopic fat reduction after bariatric surgery and T2D resolution is uncertain.
8 CitationsSource
#1Sebastian D. Parlee (Dal: Dalhousie University)H-Index: 14
#2Yan Wang (Dal: Dalhousie University)H-Index: 2
Last.Kerry B. Goralski (Dal: Dalhousie University)H-Index: 20
view all 8 authors...
Objective Bariatric surgery remains the most effective treatment for obesity and metabolic syndrome. Surgical benefit arises from early-phase resolution of hyperglycemia and late-phase weight loss. The adipokine chemerin is of interest given its roles in immunity, adipogenesis, and metabolism. The study objective was to examine the effects of biliopancreatic diversion with duodenal switch (BPD-DS) on plasma chemerin in the early and late post-operative stages. Methods 83 adults with obesity unde...
7 CitationsSource
#1Jacinthe Leclerc (Laval University)
#2Nadine Bonneville (Laval University)H-Index: 2
Last.Paul Poirier (Laval University)H-Index: 55
view all 6 authors...
AbstractWeight loss is a popular topic and may be of serious concern for many patients. Even with the abundant literature on obesity and cardiometabolic risk, it is always challenging to demystify and reinforce the determinants of safe approaches to lose weight. Measures of central obesity are essential to characterize the patient’s adiposity distribution and should be part of the routine medical examination. Beyond this, screening for fasting lipids and glucose are important for the assessment ...
Source
#1Marc Lapointe (Laval University)H-Index: 10
#2Paul Poirier (Laval University)H-Index: 55
Last.Katherine Cianflone (Laval University)H-Index: 31
view all 6 authors...
Background Although no receptor has yet been identified, changes in circulating levels of the adipokine designated as Omentin have been demonstrated in obesity and related comorbidities such as cardiovascular disease, insulin resistance, metabolic syndrome and chronic inflammation.
13 CitationsSource
#1HuiLing Lu (Laval University)H-Index: 13
#2Ponce Cedric Fouejeu Wamba (Laval University)H-Index: 1
Last.Katherine Cianflone (Laval University)H-Index: 31
view all 7 authors...
Purpose Vaspin (visceral-adipose-tissue-derived-serine-protease-inhibitor) is a recently identified adipokine with putative insulin-sensitizing properties. Plasma vaspin responses to surgery-induced weight loss are sparse and contradictory. Design and Participants We evaluated changes in vaspin levels and relationship to post-operative outcomes in men (n = 22) and women (n = 55) undergoing biliopancreatic-diversion/duodenal-switch bariatric surgery. Body composition and plasma parameters were me...
5 CitationsSource
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