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Luciana Yamamoto Almeida
Sao Paulo State University
116Publications
5H-index
105Citations
Publications 133
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Nodular fasciitis (NF) is a benign/reactive myofibroblastic proliferative process with unknown etiology, which presents as a solitary, painless, fast-growth nodule, commonly located on the limbs and trunk; the head and neck region is affected between 10% and 20% of cases. Noteworthy, uncommon NF variants such as intravascular, intramuscular, cranial, ossifying, proliferative, and intradermal have been reported. A 64-year-old man was referred complaining of a painful swelling in the right side of...
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Carcinoma cuniculatum (CC) is a rare variant of oral squamous cell carcinoma (OSCC). To date, 50 cases of oral CC have been reported. A 67-year-old white female patient presented complaining of a painless tumor mass in the left mandibular body with several months of evolution. Previous dental history indicated extraction of teeth #37 and #38 and chronic osteomyelitis. Intraoral examination revealed an irregular exophytic mass in the region of the extracted teeth, which exhibited a yellow purulen...
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Objective Tetraspanins are proteins involved in several cellular processes, including association with tumor progression. In this study, the immunoexpression of tetraspanins in head and neck squamous cell carcinoma (HNSCC) were assessed, aiming to evaluate the participation of these molecules in carcinogenesis. Study Design An immunohistochemical study was carried out using the tissue microarray technique to evaluate the tetraspanins CD9 and CD63. One hundred and twenty-one HNSCCs were analyzed ...
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Objective Oropharyngeal squamous cell carcinomas (OPSCCs), especially those expressing human papilloma virus (HPV), are associated with a better prognosis than HPV-negative OPSCC and oral squamous cell carcinoma (OSCC). Among them, OPSCC often presents nonkeratinizing and hybrid than keratinizing histologic subtypes, as well as higher proliferation index. Thus, this study aims to analyze the relationship of epithelial-mesenchymal transition (EMT) and cell proliferation markers in OPSCC and OSCC....
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Epidermoid cysts (ECs) are rare and occur in the head and neck region with an incidence from 1.6% to 7%. In the oral cavity, EC represents less than 0.01% of all cysts. To date, approximately 80 EC cases have been reported. We report a case of a 26-year-old man who developed a large EC in the midline floor of the mouth, leading to speech and swallowing difficulties and causing swelling in the submental region. Ultrasonography and fine needle aspiration confirmed the cystic nature of the lesion. ...
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Oral melanoacanthoma is an uncommon pigmented lesion of the oral mucosa characterized by the presence of acanthosis and dendritic pigment-laden melanocytes located in the prickle cell layer of the epithelium. Pseudomelanocytic nests (PNs) represent cellular aggregates of keratinocytes, macrophages, and melanocytes, usually located in close relationship with lichenoid inflammation, which if not recognized can be misdiagnosed as melanoma. A 41-year-old white woman was referred presenting a pigment...
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Plasma cell cheilitis (PCC) is an unusual benign plasma cell proliferative disease of an unknown etiology that clinically presents as erythematous-violaceous plaques, ulcerations, or eruptions often affecting the lower lip. PCC is known to respond poorly to corticosteroid treatment. A 43-year-old male presented with multiple painful hemorrhagic crusts on the lower lip that had developed over 1 month. An incisional biopsy was performed and microscopy showed a bandlike inflammatory cell infiltrati...
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Objective Current evidences support that squamous cell carcinomas (SCCs) of the oral cavity (OSCC) and oropharynx (OPSCC) are distinct and unique, with differences on its pathogenesis, treatment, and prognosis. SMARCB1/INI1 is a potent tumor suppressor, whereas nuclear protein in testis (NUT) antibody identifies midline carcinoma (NMC), a rare aggressive carcinoma typically located on the midline of the head and neck. Although with different clinicopathological features, OPSCC and NMC share anat...
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Objective Squamous cell carcinoma (SCC) of the head and neck region with neuroendocrine differentiation are rare neoplasms. These tumors can be poorly differentiated and usually have tendency for aggressive clinical behavior and propensity for both regional and distant metastasis. Their diagnosis is based on morphology and confirmation of origin by immunohistochemistry. The purpose of this study was to investigate the neuroendocrine differentiation profile in oral SSC (OSCC) and oropharyngeal SC...
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Juvenile ossifying fibroma (JOF) is a benign bone-producing fibrous neoplasm of the skeleton. Clinically, children and adolescents are affected without preference for sex. There are 2 clinicopathologic variants, psammomatoid and trabecular (JTOF). JOF can be aggressive, suggesting a malignant neoplasm. A 26-year-old male patient with volumetric increasing of the mandible with a history of evolution of 2 months was referred for evaluation. Intraoral examination showed expansion of both bone corti...
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