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Jianwen Cai
University of North Carolina at Chapel Hill
266Publications
41H-index
8,071Citations
Publications 266
Newest
#1Bertha Hidalgo (UAB: University of Alabama at Birmingham)H-Index: 16
#2Tamar Sofer (Brigham and Women's Hospital)H-Index: 15
Last.Adrienne M. Stilp (UW: University of Washington)H-Index: 18
view all 17 authors...
Five sequence variants in SLC16A11 (rs117767867, rs13342692, rs13342232, rs75418188, and rs75493593), which occur in two non-reference haplotypes, were recently shown to be associated with diabetes in Mexicans from the SIGMA consortium. We aimed to determine whether these previous findings would replicate in the HCHS/SOL Mexican origin group and whether genotypic effects were similar in other HCHS/SOL groups. We analyzed these five variants in 2492 diabetes cases and 5236 controls from the Hispa...
#1Frank C. Bandiera (FDA: Food and Drug Administration)H-Index: 1
#2Eliseo J. Pérez-Stable (NIH: National Institutes of Health)H-Index: 68
Last.Robert C. Kaplan (Albert Einstein College of Medicine)H-Index: 54
view all 0 authors...
Abstract Introduction Tobacco smoking and binge or excess drinking are unhealthy behaviors that frequently co-occur. Studies of Hispanics/Latinos have mostly been of Mexican Americans although there are substantial differences in smoking and drinking by heritage background. Associated with co-use by 5 subpopulations. Methods Cross-sectional data of 16,412 Hispanics/Latinos from Miami, the Bronx, Chicago and San Diego collected between 2008 and 2011 as part of the HCHS/SOL were analyzed. Smoking ...
#1Priscilla Vásquez (UCSD: University of California, San Diego)H-Index: 1
#2Ramon Durazo-Arvizu (LUC: Loyola University Chicago)H-Index: 41
Last.Martha L. Daviglus (UIC: University of Illinois at Chicago)H-Index: 39
view all 18 authors...
Physical activity is a modifiable healthy behavior that has been shown to positively influence health-related quality of life. However, research examining the link between physical activity and health-related quality of life among Hispanic/Latino adults is limited and inconsistent. The purpose of this study is to assess whether accelerometer-measured moderate-vigorous physical activity (MVPA) is associated with self-reported (a) mental health-related quality of life, and (b) physical health-rela...
#1Alex Morris (University of Oxford)H-Index: 82
#2Thu H. Le (UVA: University of Virginia)H-Index: 21
Last.Nora Franceschini (UNC: University of North Carolina at Chapel Hill)H-Index: 9
view all 72 authors...
Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function that defines CKD, in 312,468 individuals of diverse ancestry. We identify 127 distinct association signals with homogeneous effects on eGFR across ancestries and enrichment in genomic annotations including kidney-specific histone modifications. ...
#1Kenneth I. Ataga (UT: University of Tennessee)
#2David G. Wichlan (UNC: University of North Carolina at Chapel Hill)H-Index: 2
Last.Alan L. Hinderliter (UNC: University of North Carolina at Chapel Hill)H-Index: 49
view all 0 authors...
#1Alberto R. Ramos (UM: University of Miami)H-Index: 8
#2Wassim Tarraf (WSU: Wayne State University)H-Index: 16
Last.Hector M. González (UCSD: University of California, San Diego)H-Index: 24
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Abstract Introduction To determine if sleep-disordered breathing (SDB), daytime sleepiness, insomnia, and sleep duration predict seven-year neurocognitive decline in US Hispanics/Latinos (N = 5247). Methods The exposures were baseline SDB, daytime sleepiness, insomnia, and sleep duration. The outcomes were change in episodic learning and memory (B-SEVLT-Sum and SEVLT-Recall), language (word fluency [WF]), processing speed (Digit Symbol Substitution), and a cognitive impairment screener (Six-item...
#1Eric R. Kallwitz (Loyola University Medical Center)H-Index: 9
#2Bamidele O. Tayo (LUC: Loyola University Chicago)H-Index: 24
Last.Scott J. Cotler (Loyola University Medical Center)H-Index: 27
view all 7 authors...
Background & Aims Nonalcoholic fatty liver disease (NAFLD) disproportionally affects Hispanic/Latino populations. However, the magnitude varies among Hispanic/Latino ethnic groups. We investigated the mechanisms of these disparities. Methods We examined associations of NAFLD-associated genetic variants and continental ancestry with suspected NAFLD, levels of alanine aminotransferase (ALT), and liver fibrosis using data from the Hispanic Community Health Study/Study of Latinos—a population-based ...
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