Anke Hannemann
University of Greifswald
Publications 29
#1Jan TerockH-Index: 5
#2Anke Hannemann (University of Greifswald)H-Index: 14
Last.Hans J. Grabe (German Center for Neurodegenerative Diseases)H-Index: 60
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Abstract Objective Low levels of vitamin D were found to be associated with different mental disorders. However, the role of vitamin D in the pathogenesis of PTSD is unclear. In this study, we aimed at investigating whether PTSD is linked to reduced vitamin D levels and vitamin D deficiency. Moreover, we sought to investigate the role of the vitamin D-binding protein (also group-specific component or Gc) by testing if two functional polymorphisms (rs4588 and rs7041) were associated with vitamin ...
Objective. Aldosterone and high-density lipoprotein cholesterol (HDL-C) are involved in many pathophysiological processes that contribute to the development of cardiovascular diseases. Previously, associations between the concentrations of aldosterone and certain components of the lipid metabolism in the peripheral circulation were suggested, but data from the general population is sparse. We therefore aimed to assess the associations between aldosterone and HDL-C, low-density lipoprotein choles...
4 CitationsSource
#1Anne GrotevendtH-Index: 11
#2Henri WallaschofskiH-Index: 54
Last.Anke HannemannH-Index: 14
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Purpose Chronic inflammation is an age-independent and body mass index-independent contributor to the development of multi-morbidity. Alterations of the renin-angiotensin-aldosterone system are observed within the context of proinflammatory states. We assessed circulating aldosterone, renin, and inflammatory biomarker concentrations in healthy, normotensive subjects and patients with primary aldosteronism.
2 CitationsSource
#1V. LangeH-Index: 1
#2Marcus DoerrH-Index: 51
Last.Anke HannemannH-Index: 14
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Objective. It is highly debated whether associations between osteoporosis and atherosclerosis are independent of cardiovascular risk factors. We aimed to explore the associations between quantitative ultrasound (QUS) parameters at the heel with the carotid artery intima-media thickness (IMT), the presence of carotid artery plaques, and the ankle-brachial index (ABI). Methods. The study population comprised 5680 men and women aged 20–93 years from two population-based cohort studies: Study of Hea...
2 CitationsSource
Context: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Aldosterone excess can cause DNA damage in vitro and in vivo. Single case reports have indicated a coincidence of PA with renal cell carcinoma and other tumors. However, the prevalence of benign and malignant neoplasms in patients with PA has not yet been studied. Patients and Design: In the multicenter MEPHISTO study, the prevalence of benign and malignant tumors was investigated in 335 patients with confirm...
4 CitationsSource
#1R. M. BergH-Index: 1
#2Henri WallaschofskiH-Index: 54
Last.Anke HannemannH-Index: 14
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Obesity is often considered to have a protective effect against osteoporosis. On the other hand, several recent studies suggest that adipose tissue may have detrimental effects on bone quality. We therefore aimed to investigate the associations between body mass index (BMI), waist circumference (WC), visceral adipose tissue (VAT) or abdominal subcutaneous adipose tissue (SAT), and bone stiffness. The study involved 2685 German adults aged 20–79 years, who participated in either the second follow...
15 CitationsSource
#1Katharina LangH-Index: 3
Last.Stefanie HahnerH-Index: 45
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#1Wolfgang Lieb (CAU: University of Kiel)H-Index: 42
#2Ming-Huei Chen (BU: Boston University)H-Index: 34
Last.Ramachandran S. Vasan (BU: Boston University)H-Index: 150
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Background— The renin–angiotensin–aldosterone system (RAAS) is critical for regulation of blood pressure and fluid balance and influences cardiovascular remodeling. Dysregulation of the RAAS contributes to cardiovascular and renal morbidity. The genetic architecture of circulating RAAS components is incompletely understood. Methods and Results— We meta-analyzed genome-wide association data for plasma renin activity (n=5275), plasma renin concentrations (n=8014), and circulating aldosterone (n=13...
15 CitationsSource
#1Nicole Aumann (University of Greifswald)H-Index: 7
Last.Christa MeisingerH-Index: 87
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Background/Aims: Due to the increasing prevalence of risk factors for chronic kidney disease (CKD), kidney dysfunction becomes a major public health problem. We investigated the CKD prevalence and determined to what extent the variation of risk factors explains the different CKD prevalence in Germany. Methods: We analyzed data from 6,054 participants, aged 31 to 82 years, from the Study of Health in Pomerania (SHIP-1) in Northeast Germany and the Cooperative Health Research in the Region of Augs...
3 CitationsSource
#1Anke HannemannH-Index: 14
#2Rainer RettigH-Index: 35
Last.Henri WallaschofskiH-Index: 54
view all 7 authors...
Background Increasing evidence suggests that aldosterone promotes renal damage. Since data on the association between aldosterone and renal function in the general population are sparse, we chose to address this issue. We investigated the associations between the plasma aldosterone concentration (PAC) or the aldosterone-to-renin ratio (ARR) and the estimated glomerular filtration rate (eGFR) in a sample of adult men and women from Northeast Germany.
6 CitationsSource