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Albert Lecube
University of Lleida
EndocrinologyType 2 diabetesObesityDiabetes mellitusMedicine
130Publications
23H-index
1,814Citations
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Publications 169
Newest
#1Júlia Carmona-Maurici (University of Barcelona)
#2Elena Cuello (University of Lleida)H-Index: 1
view all 15 authors...
Abstract Objectives The main cause of death in obese individuals is cardiovascular disease precipitated by atherosclerosis. Endothelial dysfunction and inflammation are considered early events in the development of the disease. The aim of this study was to identify biomarkers of subclinical atherosclerosis in patients with morbid obesity by comparing clinical, vascular and biochemical parameters indicative of endothelial dysfunction in patients with and without atheromatous plaque and monitoring...
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#1Enric Sánchez (University of Lleida)H-Index: 4
#2Chadia Mizab (University of Lleida)H-Index: 1
Last. Jessica González (University of Lleida)H-Index: 1
view all 14 authors...
In order to compare spirometric maneuvers in adults according to the presence of type 1 diabetes, a case-control study including 75 patients with type 1 diabetes and 75 controls matched by sex, age, and body mass index were designed. In addition, 75 patients with type 1 diabetes were added to examine the potential the impact of subcutaneous insulin therapy on pulmonary function. Lung function measurements were assessed according to the global initiative for chronic obstructive lung disease guide...
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#1Maria-Dolores Santos (University of Lleida)
#2Miquel ButiH-Index: 2
Last. Marta Bueno (University of Lleida)H-Index: 2
view all 11 authors...
Introduction: Paired cohort investigations assessing the evolution of anthropometric indices are scarce. Here we assessed the 10-year evolution of BMI, total body fat, and lean body mass in 50,019 participants aged 18 to 90 years at the time of first assessment. Material and Methods: A retrospective cohort study using an electronic database that contains anonymized, longitudinal data from Primary Care medical records covering the 2007–2008 and 2017–2018 periods. Total body fat was estimated usin...
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#1Liliana Gutiérrez-Carrasquilla (University of Lleida)H-Index: 2
#2Carolina López-Cano (University of Lleida)H-Index: 4
Last. Cristina Hernández (Autonomous University of Barcelona)H-Index: 46
view all 12 authors...
Type 2 diabetes exerts a negative impact on sleep breathing. It is unknown whether a long-term improvement in glycemic control ameliorates this effect. We conducted an interventional study with 35 patients with type 2 diabetes and obstructive sleep apnea (OSA) to explore this. At home, sleep breathing parameters were assessed at baseline and after a 4-month period in which antidiabetic therapy was intensified. Patients who decreased their body mass index ≥2kg/m2 were excluded. Those with an HbA1...
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#1Enric Sánchez (University of Lleida)H-Index: 4
#2Angels Betriu (University of Lleida)H-Index: 19
Last. Albert Lecube (University of Lleida)H-Index: 5
view all 11 authors...
Purpose Adherence to Mediterranean diet (MedDiet) and physical activity have been associated to lower cardiovascular risk and mortality. Our purpose was to test the modification of advanced glycation end-products (AGEs) as one of the underlying mechanisms explaining this relationship.
1 CitationsSource
#1Enric Sánchez (University of Lleida)H-Index: 4
#2Marta Gómez Sánchez (University of Lleida)H-Index: 1
Last. Marta Hernández (University of Lleida)H-Index: 15
view all 14 authors...
OBJECTIVE: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to assess the usefulness of these anthropometric indices to detect subclinical atheromatous disease. METHODS: A cross-sectional study with 6,809 middle-aged subjects (mean age, 57 [53-63] years) with lo...
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#2Gemma LlauradóH-Index: 11
Last. Sonia Fernández-VeledoH-Index: 15
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In the article cited above, the clinical trial number was mistakenly given as NCT1410475, clinicaltrials.gov. …
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#1Enric Sánchez (University of Lleida)H-Index: 4
#2Angels BetriuH-Index: 19
Last. Albert Lecube (University of Lleida)H-Index: 23
view all 14 authors...
Background Prediabetes has recently been associated with subclinical atheromatous disease in the middle-aged population. Our aim was to characterize atheromatous plaque burden by the number of affected territories and the total plaque area in the prediabetes stage.
3 CitationsSource
#1Enric Sánchez (University of Lleida)H-Index: 4
#2Angels BetriuH-Index: 19
Last. Montse Martínez-AlonsoH-Index: 1
view all 28 authors...
Aim: Advanced glycation end-products (AGEs) have been involved in the atherogenic process in the high-risk population. The goal of this study was to demonstrate that AGEs are related to subclinical atheromatous disease in subjects with low to moderate vascular risk. Methods: A cross-sectional study in which 2,568 non-diabetic subjects of both sexes without cardiovascular disease were included. Subcutaneous content of AGEs was assessed by skin autofluorescence (SAF) and subclinical atheromatous d...
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#1Albert Lecube (University of Lleida)H-Index: 23
#2Carolina López-Cano (University of Lleida)H-Index: 4
Obesity is a multifactorial and complex disease that continues to challenge patients and professional caregivers [...]
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