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João Palermo-Neto
University of São Paulo
244Publications
29H-index
2,988Citations
Publications 244
Newest
Published on Apr 1, 2019in Research in Veterinary Science 1.62
Atilio Sersun Calefi7
Estimated H-index: 7
(USP: University of São Paulo),
Catarina Augusta de Queiroz Nunes (USP: University of São Paulo)+ 3 AuthorsJoão Palermo-Neto29
Estimated H-index: 29
(USP: University of São Paulo)
Abstract Heat stress has a relevant effect on animal health and productivity. Stress and environmental changes can contribute to disease development, such as avian necrotic enteritis (NE). The goal of this study was to analyze the effects of heat stress applied to broiler chickens in an experimental model of co-infection with Clostridium perfringens and Eimeria spp. Therefore, the current study was designed to analyze the effect of heat stress to broiler chickens in an experimental model of infe...
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Published on Apr 1, 2019in Veterinary Immunology and Immunopathology 1.63
Atilio Sersun Calefi7
Estimated H-index: 7
(USP: University of São Paulo),
W.M. Quinteiro-Filho11
Estimated H-index: 11
(USP: University of São Paulo)
+ 9 AuthorsPaulo César Maiorka10
Estimated H-index: 10
(USP: University of São Paulo)
Abstract Information on the dynamics of the chicken immune system during bacterial or parasite challenge in the presence or absence of stressful situations may provide a better understanding of the complex mechanisms behind these diseases. Necrotic enteritis (NE) had been controlled previously by the proper use of antimicrobial agents; however, more recently, NE has reemerged in many countries. The imposed restrictions on antimicrobial use and/or the intensive productive programs implemented by ...
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Published on Mar 1, 2018in International Immunopharmacology 3.12
Talita Rossetto Barreto1
Estimated H-index: 1
(USP: University of São Paulo),
Carolina Costola-de-Souza6
Estimated H-index: 6
(USP: University of São Paulo)
+ 5 AuthorsAdriano Zager12
Estimated H-index: 12
(USP: University of São Paulo)
Abstract The dopaminergic antagonist drug Domperidone has immunomodulatory effects. We investigated the effects of repeated Domperidone treatment in a model of Lypopolyssacharide (LPS)-induced acute lung inflammation. Adult C57BL/6J mice were treated with either Vehicle or Domperidone for 5 days, and challenged intranasally with LPS in the following day. The behavior of mice was analyzed in the open field and elevated plus-maze test before and 24 h after LPS challenge. The bronchoalveolar lavage...
2 Citations Source Cite
Adriano Zager12
Estimated H-index: 12
(USP: University of São Paulo),
Wesley Nogueira Brandão5
Estimated H-index: 5
(USP: University of São Paulo)
+ 5 AuthorsJoão Palermo-Neto29
Estimated H-index: 29
(USP: University of São Paulo)
Abstract The wake-promoting drug Modafinil has been used for many years for treatment of Narcolepsy and Excessive Daytime Sleepiness, due to a dopamine-related psychostimulant action. Recent studies have indicated that Modafinil prevents neuroinflammation in animal models. Thus, the aim of the present study was to evaluate the effect of Modafinil pretreatment in the Lipopolysaccharide (LPS)-induced sickness and depressive-like behaviors. Adult male C57BL/6J mice were pretreated with Vehicle or M...
5 Citations Source Cite
Adriano Zager12
Estimated H-index: 12
(USP: University of São Paulo),
Wesley Nogueira Brandão5
Estimated H-index: 5
(USP: University of São Paulo)
+ 9 AuthorsGiuseppe Plazzi56
Estimated H-index: 56
(UNIBO: University of Bologna)
Abstract The wake-promoting drug Modafinil has been used for treatment of sleep disorders, such as Narcolepsy, excessive daytime sleepiness and sleep apnea, due to its stimulant action. Despite the known effect of Modafinil on brain neurochemistry, particularly on brain dopamine system, recent evidence support an immunomodulatory role for Modafinil treatment in neuroinflammatory models. Here, we aimed to study the effects of in vitro and in vivo Modafinil treatment on activation, proliferation, ...
1 Citations Source Cite
Published on Dec 1, 2017in Physiology & Behavior 2.52
Eduardo Kenji Hamasato1
Estimated H-index: 1
(USP: University of São Paulo),
Dennis Lovelock2
Estimated H-index: 2
(Binghamton University)
+ 1 AuthorsTerrence Deak39
Estimated H-index: 39
(Binghamton University)
Abstract Acute illness not only reduces the expression of social behavior by sick rodents, but can also lead to avoidance responses when detected by healthy, would-be social partners. When healthy animals interact with a sick partner, an intriguing question arises: does exposure to a sick conspecific elicit an anticipatory immune response that would facilitate defense against future infection? To address this question, healthy adult male Sprague-Dawley rats ( N = 64) were given a brief social in...
3 Citations Source Cite
Published on Feb 1, 2017in Physiology & Behavior 2.52
Thalita R.M. Machado1
Estimated H-index: 1
(USP: University of São Paulo),
Glaucie Jussilane Alves8
Estimated H-index: 8
(USP: University of São Paulo)
+ 1 AuthorsJoão Palermo-Neto29
Estimated H-index: 29
(USP: University of São Paulo)
Abstract Cohabitation with Ehrlich ascitic tumor-injected conspecifics induces behavioral, neurochemical, endocrine and immune changes indicative of stress and immune impairment in female mice. The present work analyzed the effects of similar cohabitation in Swiss and Balb/C male mice. At least 12 pairs of male mice were divided into a control group and an experimental group. On experimental day 1 (ED1), one animal within each experimental pair was inoculated with 5 × 10 6 Ehrlich tumor cells in...
1 Citations Source Cite
Published on Jan 1, 2017in Neuroimmunomodulation 2.24
Rafael Oliveira Margatho2
Estimated H-index: 2
,
Cristina de Oliveira Massoco11
Estimated H-index: 11
+ 5 AuthorsJoão Palermo-Neto29
Estimated H-index: 29
Objectives: Cohabitation with Ehrlich tumor-bearing (ETB) mice induced behavioral, neurochemical, hormonal, and immune effects in the conspecifics as a consequenc
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Published on Oct 1, 2016in Brain Behavior and Immunity 6.31
Adriano Zager12
Estimated H-index: 12
(USP: University of São Paulo),
Rafael Oliveira Margatho2
Estimated H-index: 2
(USP: University of São Paulo)
+ 3 AuthorsJoão Palermo-Neto29
Estimated H-index: 29
(USP: University of São Paulo)
Modafinil is a psychostimulant drug that is used to treat Narcolepsy and Excessive Daytime Sleepiness, due to a dopamine-related action. Recent studies indicated that Modafinil prevents inflammation in animal models of neurodegeneration. However, the effect of Modafinil on the behavioral changes induced by systemic inflammation is still unknown. Thus, the aim of the present study was to evaluate the effect of Modafinil pretreatment in the Lipopolysaccharide (LPS)-induced sickness behavior, and d...
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