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Dong Dong
East China Normal University
38Publications
17H-index
1,653Citations
Publications 38
Newest
#1Zhenyu Bao (PKU: Peking University)H-Index: 1
#2Zhen Yang (Fudan University)H-Index: 1
Last.Dong Dong (ECNU: East China Normal University)H-Index: 17
view all 6 authors...
17 CitationsSource
#1Yijie Ma (Fudan University)H-Index: 1
#2Tong Luo (ECNU: East China Normal University)H-Index: 1
Last.Yilin Wang (Fudan University)H-Index: 1
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Abstract Dysregulation of long non-coding RNAs (lncRNAs) plays critical roles in a variety of biological processes. Recent studies have documented that lncRNAs can function as potential biomarkers in cancer prognosis, however, little is known in hepatocellular carcinoma (HCC). To identify lncRNA signatures that have prognostic values in HCC, we analyzed lncRNA expression profiles of 364 HCC patients from The Cancer Genome Atlas (TCGA) dataset. A set of four lncRNAs was identified to be significa...
6 CitationsSource
#1Guantao Zheng (ECNU: East China Normal University)H-Index: 4
#2Yijie Ma (ECNU: East China Normal University)H-Index: 1
Last.Dong Dong (ECNU: East China Normal University)H-Index: 17
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7 CitationsSource
#1Qiuyuan Yin (ECNU: East China Normal University)H-Index: 3
#2Yijian Zhang (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last.Yi-Hsuan Pan (ECNU: East China Normal University)H-Index: 7
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Abstract Bats are the only mammals capable of self-powered flying. Many bat species hibernate in winter. A reversible control of cerebral activities is critical for bats to accommodate a repeated torpor-arousal cycle during hibernation. Little is known about the molecular mechanisms that regulate neuronal activities in torpid bats. In this study, Rhinolophus ferrumequinum bat brain proteins were fractionated, and their abundance in active and torpid states was compared. Results of 2D gel-based p...
1 CitationsSource
#1Dong Dong (ECNU: East China Normal University)H-Index: 17
#2Ming Lei (ECNU: East China Normal University)H-Index: 4
Last.Shuyi Zhang (Shenyang Agricultural University)H-Index: 40
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15 CitationsSource
#1Dong DongH-Index: 17
#2Yang ZouH-Index: 1
Last.Zhihong WuH-Index: 18
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// Dong Dong 1, 2, * , Yang Zou 1, * , Pan Zhang 1 , Zhihong Wu 2, 3 1 Laboratory of Molecular Ecology and Evolution, Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, P.R. China 2 Beijing Key Laboratory for Genetic Research of Bone and Joint Disease, Beijing, 100730, P.R. China 3 Central laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, P.R. China * These authors co...
2 CitationsSource
Bats, order Chiroptera, are one of the largest monophyletic clades in mammals. Based on morphology and behaviour bats were once differentiated into two suborders Megachiroptera and Microchiroptera Recently, researchers proposed alternative views of chiropteran classification (suborders Yinpterochiroptera and Yangochiroptera) based on morphological, molecular and fossil evidence. Since genome-scale data can significantly increase the number of informative characters for analysis, transcriptome RN...
28 CitationsSource
#1Yang Zou (ECNU: East China Normal University)H-Index: 1
#2Xiaojian Shao (McGill University)
Last.Dong Dong (ECNU: East China Normal University)H-Index: 17
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Understanding the determinants of protein evolutionary rates is one of the most fundamental evolutionary questions. Previous studies have revealed that many biological variables are tightly associated with protein evolutionary rates in mammals. However, the dominant role of these biological variables and their combinatorial effects to evolutionary rates of mammalian proteins are still less understood. In this work, we derived a quantitative model to correlate protein evolutionary rates with the ...
Source
#1Peihua Zhao (ECNU: East China Normal University)H-Index: 1
#2David M. Irwin (U of T: University of Toronto)H-Index: 36
Last.Dong Dong (ECNU: East China Normal University)H-Index: 17
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The issue of what factors shape the gut microbiota has been studied for years. However, questions on the contribution of host genetics to the colonizing process of the gut microbiota and to the extent that host genetics affect the gut microbiota have not yet been clearly answered. Most recently published reports have concluded that host genetics make a smaller contribution than other factors, such as diet, in determining the gut microbiota. Here we have exploited the increasing amount of fecal 1...
2 CitationsSource
#1Guantao Zheng (ECNU: East China Normal University)H-Index: 4
#2Pan Zhang (ECNU: East China Normal University)H-Index: 1
Last.Dong Dong (ECNU: East China Normal University)H-Index: 17
view all 4 authors...
Transcriptional regulatory cascades are always triggered through the combinatorial interplay between transcription factors (TFs) and microRNAs (miRNAs) in eukaryotes. However, it is still a very substantial undertaking to dynamically profile their coordinated actions. In this work, we compared the differences in TFBS numbers between miRNA targets and non-targets, and found that miRNA targets tend to have more TFBS numbers. With the attempt to comprehensively understand the combinatorial action o...
1 CitationsSource
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