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Nardeli Boufleur
Universidade Federal de Santa Maria
26Publications
16H-index
475Citations
Publications 26
Newest
#1Patrícia Reckziegel (USP: University of São Paulo)H-Index: 2
#2Verônica Tironi Dias (UFSM: Universidade Federal de Santa Maria)H-Index: 14
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 10 authors...
Abstract The effect of the antioxidant gallic acid (GA) on Pb toxicity in blood, liver and kidney was investigated in the present study. Rats Wistar received Pb nitrate (50 mg/Kg/day, i.p., 5 days) followed by GA (13.5 mg/Kg, p.o., 3 days) or a chelating agent (EDTA, 55 mg/Kg, i.p.). As result, Pb decreased body weight, hematocrit and blood δ-aminolevulinic acid dehydratase (ALA-D) activity. In addition, high Pb levels were observed in blood and tissues, together with increased (1) lipid peroxid...
18 CitationsSource
#1Fábio Teixeira Kuhn (UFSM: Universidade Federal de Santa Maria)H-Index: 9
#2Fabíola Trevizol (UFSM: Universidade Federal de Santa Maria)H-Index: 11
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 12 authors...
Abstract Chronic consumption of processed food causes structural changes in membrane phospholipids, affecting brain neurotransmission. Here we evaluated noxious influences of dietary fats over two generations of rats on amphetamine (AMPH)-conditioned place preference (CPP). Female rats received soybean oil (SO, rich in n-6 fatty acids (FA)), fish oil (FO, rich in n-3 FA) and hydrogenated vegetable fat (HVF, rich in trans fatty acids (TFA)) for two successive generations. Male pups from the 2nd g...
13 CitationsSource
#1Caren Tatiane de David Antoniazzi (UFSM: Universidade Federal de Santa Maria)H-Index: 9
#2Nardeli Boufleur (UFSM: Universidade Federal de Santa Maria)H-Index: 16
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 11 authors...
Abstract This study investigated the influence of neonatal handling on amphetamine-induced conditioned place preference (CPP), as well as the consequent anxiety-like symptoms and oxidative status related to drug abstinence in young rats. Male pups were exposed to tactile stimulation (TS) or neonatal isolation (NI) for 10 min every day from postnatal day one (PND1) to PND21. After being weaned (PND22), pups were separated by handling type until PND40, when treatment with amphetamine (AMPH-4 mg/kg...
9 CitationsSource
#1Caren Tatiane de David Antoniazzi (UFSM: Universidade Federal de Santa Maria)H-Index: 9
#2Nardeli Boufleur (UFSM: Universidade Federal de Santa Maria)H-Index: 16
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 10 authors...
Abstract We investigated the influence of neonatal handling on cocaine-induced conditioned place preference (CPP), anxiety-like symptoms and oxidative status related to drug abstinence in young rats. Pups were submitted to tactile stimulation (TS) or neonatal isolation (NI 10 or NI 60 ) after birth, and then were submitted to CPP performed with cocaine. TS group did not show place preference, while unhandled (UH), NI 10 and NI 60 rats did. Handling was related to anxiety-like symptoms per se in ...
10 CitationsSource
#1Fábio Teixeira Kuhn (UFSM: Universidade Federal de Santa Maria)H-Index: 9
#2Karine Roversi (UFSM: Universidade Federal de Santa Maria)H-Index: 9
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 13 authors...
Abstract The current Western diet often provides considerable amounts of saturated and trans fatty acids (TFA), whose incorporation into neuronal membranes has been implicated in changes of brain neurochemical functions. Such influence has caused concerns due to precipitation of neuropsychiatric disorders, whose data are still unclear. Here we evaluated the influence of different fats on preference parameters for amphetamine (AMPH): adolescent rats were orally supplemented with soybean oil (SO, ...
21 CitationsSource
#1Nardeli Boufleur (UFSM: Universidade Federal de Santa Maria)H-Index: 16
#2Caren Tatiane de David Antoniazzi (UFSM: Universidade Federal de Santa Maria)H-Index: 9
Last.Marilise Escobar BurgerH-Index: 24
view all 13 authors...
This study investigated the influence of neonatal handling on behavioral and biochemical consequences of chronic mild stress (CMS) in adulthood. Male rat pups were submitted to daily tactile stimulation (TS) or maternal separation (MS), from postnatal day 1 (PND1) to postnatal day 21 (PND21), for 10 min/day. In adulthood, half the number of animals were exposed to CMS for 3 weeks and submitted to behavioral testing, including sucrose preference (SP), elevated plus maze (EPM), and defensive buryi...
25 CitationsSource
#1Liz Girardi Müller (UFSM: Universidade Federal de Santa Maria)H-Index: 10
#2C.S. Pase (UFSM: Universidade Federal de Santa Maria)H-Index: 18
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 12 authors...
Abstract The hepatoprotective activity of the aqueous extract of the shells of pecan nut was investigated against ethanol-induced liver damage. This by-product of the food industry is popularly used to treat toxicological diseases. We evaluated the phytochemical properties of pecan shell aqueous extract (AE) and its in vitro and ex vivo antioxidant activity. The AE was found to have a high content of total polyphenols (192.4 ± 1.9 mg GAE/g), condensed tannins (58.4 ± 2.2 mg CE/g), and antioxidan...
24 CitationsSource
#1Dalila M. BenvegnúH-Index: 17
#2Raquel Cristine Silva Barcelos (UFSM: Universidade Federal de Santa Maria)H-Index: 18
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 16 authors...
This study investigated the protective effect of pecan nut (Carya illinoensis) shell aqueous extract (AE) on the oxidative and morphological status of rat testis treated with cyclophosphamide (CP). Wistar rats received water or AE (5%) ad libitum for 37 days. On day 30, half of each group received a single intraperitoneal administration of vehicle or CP 200 mg/kg. After 7 days, the animals were killed and their testis removed. Rats treated with CP presented reduced levels of lactate dehydrogenas...
5 CitationsSource
#1Dalila M. Benvegnú (UFSM: Universidade Federal de Santa Maria)H-Index: 17
#2Raquel Cristine Silva Barcelos (UFSM: Universidade Federal de Santa Maria)H-Index: 18
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 11 authors...
Abstract Haloperidol is the most widely used antipsychotic drug in the treatment of psychiatric disorders. Despite its satisfactory therapeutic effect, its chronic use is related to severe motor side effects. Here, we investigate the incidence of motor side effects of haloperidol-loaded nanocapsules when compared to free haloperidol and the relation with oxidative stress (OS) development. Both vehicle (B-NcFO) and haloperidol loaded polysorbate-coated nanocapsules suspension (H-NcFO) prepared wi...
16 CitationsSource
#1Nardeli Boufleur (UFSM: Universidade Federal de Santa Maria)H-Index: 16
#2Caren Tatiane de David Antoniazzi (UFSM: Universidade Federal de Santa Maria)H-Index: 9
Last.Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
view all 13 authors...
Abstract In this study we evaluated the influence of neonatal tactile stimulation (TS) on behavioral and biochemical effects related to a low dose of diazepam (DZP) in adult rats. Male pups of Wistar rats were handled (TS) daily from PND1 to PND21 for 10 min, while unhandled (UH) rats were not touched. In adulthood, half the animals of each group received a single administration of diazepam (0.25 mg/kg body weight i.p.) or vehicle and then were submitted to behavioral and biochemical evaluations...
9 CitationsSource
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