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Tobias Wang
Aarhus University
AnatomyEndocrinologyHypoxia (medical)Blood pressureBiology
340Publications
33H-index
3,984Citations
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Publications 348
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#1William Joyce (U of O: University of Ottawa)
#2Tobias Wang (AU: Aarhus University)H-Index: 33
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#1Warren W. Burggren (UNT: University of North Texas)H-Index: 46
#2Renato Filogonio (UFSCar: Federal University of São Carlos)H-Index: 4
Last. Tobias Wang (AU: Aarhus University)H-Index: 33
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This review explores the long-standing question: 'Why do cardiovascular shunts occur?' An historical perspective is provided on previous research into cardiac shunts in vertebrates that continues to shape current views. Cardiac shunts and when they occur is then described for vertebrates. Nearly 20 different functional reasons have been proposed as specific causes of shunts, ranging from energy conservation to improved gas exchange, and including a plethora of functions related to thermoregulati...
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#1Maja Fuhlendorff Jensen (AU: Aarhus University)
#2Signe Nedergaard (AU: Aarhus University)
Last. Tobias Wang (AU: Aarhus University)H-Index: 33
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Abstract Endothelin-1 (ET-1) is a very potent vasoactive peptide released from endothelial cells, and ET-1 plays an important role in the maintenance and regulation of blood pressure in mammals. ET-1 signaling is mediated by two receptors: ETA and ETB. In mammals, ETA receptors are located on vascular smooth muscle where they mediate vasoconstriction. ETB receptors located on the endothelium mediate vasodilatation through the release of nitric oxide, whereas stimulation of ETB receptors placed o...
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#1Le Thi Hong Gam (Can Tho University)H-Index: 3
#2Do Thi Thanh Huong (Can Tho University)H-Index: 21
Last. Mark Bayley (AU: Aarhus University)H-Index: 29
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Chitala ornata is a facultative air-breathing fish, which at low temperatures shows an arterial PCO2 (PaCO2) level only slightly elevated above that of water-breathers. By holding fish with in-dwelling catheters in temperatures from 25-36°C and measuring blood gasses, we show that this animal follows the ubiquitous poikilotherm pattern of reducing pHa with increasing temperature. Surprisingly, the temperature increase caused an elevation of PaCO2 from 5 to 12 mmHg while the plasma bicarbonate co...
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Shave et al. (1) provide a highly interesting comparison of cardiac form and function in humans and chimpanzees, but, while we agree that the circulation provides important constraints on exercise performance in animals, we are concerned regarding the validity of the central tenet of the high arterial blood pressure and its related measures in chimpanzees. Blood … [↵][1]1To whom correspondence may be addressed. Email: b.jensen{at}amsterdamumc.nl. [1]: #xref-corresp-1-1
1 CitationsSource
#1William Joyce (U of O: University of Ottawa)
#2Tobias Wang (AU: Aarhus University)H-Index: 33
ABSTRACT In the 1950s, Arthur C. Guyton removed the heart from its pedestal in cardiovascular physiology by arguing that cardiac output is primarily regulated by the peripheral vasculature. This is counterintuitive, as modulating heart rate would appear to be the most obvious means of regulating cardiac output. In this Review, we visit recent and classic advances in comparative physiology in light of this concept. Although most vertebrates increase heart rate when oxygen demands rise (e.g. durin...
2 CitationsSource
#1Mads DamkjærH-Index: 7
Last. Tobias Wang (AU: Aarhus University)H-Index: 33
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#1Tobias Wang (AU: Aarhus University)H-Index: 33
#2Daniel E. Warren (SLU: Saint Louis University)H-Index: 5
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![Figure][1] ‘Gray hair is a crown of glory, which is won by a virtuous life’ (Proverbs 16:31). Donald C. Jackson (1937–2020) analyzing lactate concentration in the shell of anoxic (and edible) Burgundy snail ( Helix pomatia ) during a research visit to Aarhus University in the summer
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#1Angela Fago (AU: Aarhus University)H-Index: 35
#2Chandrasekhar Natarajan (NU: University of Nebraska–Lincoln)H-Index: 16
Last. Darío A. Estrin (UBA: University of Buenos Aires)H-Index: 33
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Hemoglobins (Hbs) of crocodilians are reportedly characterized by unique mechanisms of allosteric regulatory control, but there are conflicting reports regarding the importance of different effecto...
1 CitationsSource
#1Mari-Ann O. Da Silva (Copenhagen Zoo)H-Index: 3
#2Jacob Thorup Gade (Copenhagen Zoo)H-Index: 1
Last. Mads F. Bertelsen (Copenhagen Zoo)H-Index: 24
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To investigate whether the thickness of the cornea in snakes correlates with overall anatomy, habitat or daily activity pattern, we measured corneal thickness using optical coherence tomography scanning in 44 species from 14 families (214 specimens) in the collection at the Natural History Museum (Denmark). Specifically, we analyzed whether the thickness of the cornea varies among species in absolute terms and relative to morphometrics, such as body length, spectacle diameter, and spectacle thic...
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