Yoshiki Masuda
Sapporo Medical University
Publications 72
#1Yuki Nakamura (Sapporo Medical University)
#2Shinya Chihara (Sapporo Medical University)H-Index: 2
Last.Yoshiki Masuda (Sapporo Medical University)H-Index: 12
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Background For continuous venovenous hemofiltration (CVVH) to achieve an adequate therapeutic effect, prolonged stable administration and a long circuit lifetime are needed. The effects of hemofilters produced using various kinds of materials on circuit lifetime in CVVH have been examined, but no studies have investigated the effects of the length, diameter, or surface coating of hollow fibers. The aim of the present study was to evaluate the circuit lifetime in CVVH retrospectively using two ty...
#1Masayuki Akatsuka (Sapporo Medical University)H-Index: 1
#2Yoshiki MasudaH-Index: 12
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Multiple organ dysfunction induced by sepsis often involves kidney injury. Extracellular histones released in response to damage-associated molecular patterns are known to facilitate sepsis-induced organ dysfunction. Recombinant human soluble thrombomodulin (rhTM) and its lectin-like domain (D1) exert anti-inflammatory effects and neutralize damage-associated molecular patterns. However, the effects of rhTM and D1 on extracellular histone H3 levels and kidney injury remain poorly understood. Our...
#1Shinya Chihara (Sapporo Medical University)H-Index: 2
#2Yoshiki Masuda (Sapporo Medical University)H-Index: 12
Last.Michiaki Yamakage (Sapporo Medical University)H-Index: 24
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Objective:We investigated the differences in biocompatibility pre- and post-dilution during continuous veno-venous hemofiltration in patients with sepsis, focusing on leukocyte and platelet function.Patients and methods:Subjects were 12 patients with septic shock who underwent veno-venous hemofiltration for acute kidney injury between March 2016 and September 2017. The first six patients received pre-dilution veno-venous hemofiltration, and the next six patients received post-dilution veno-venou...
#1T. Ito (Kadai: Kagoshima University)H-Index: 21
#2Mayumi Nakahara (Kadai: Kagoshima University)H-Index: 3
Last.Ikuro Maruyama (Kadai: Kagoshima University)H-Index: 47
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Background Nuclear histone proteins are released into the extracellular space during sepsis and act as major mediators of death. However, circulating histone levels have not been precisely quantified.
#1Osamu Nishida (Fujita Health University)H-Index: 11
#2Hiroshi Ogura (Osaka University)H-Index: 33
Last.Shigeto Oda (Chiba University)H-Index: 3
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The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 and published in the Journal of JSICM, [2017; Volume 24 (supplement 2)] and Journal of Japanese Association for Acute Medi...
#1Ikuto Otsuki (Sapporo Medical University)
#2Yoshiki Masuda (Sapporo Medical University)H-Index: 12
Last.Michiaki Yamakage (Sapporo Medical University)H-Index: 24
view all 7 authors...
#1Takashi Yamada (RMIT: RMIT University)H-Index: 23
#2Koichi Himori (RMIT: RMIT University)H-Index: 3
Last.Johanna T. Lanner (KI: Karolinska Institutet)H-Index: 18
view all 13 authors...
Severe muscle weakness concomitant with preferential depletion of myosin has been observed in several pathological conditions. Here we used the steroid-denervation (S-D) rat model, which shows dramatic decrease in myosin content and force production, to test whether electrical stimulation (ES) treatment can prevent these deleterious changes. S-D was induced by cutting the sciatic nerve and subsequent daily injection of dexamethasone for 7 days. For ES treatment, plantarflexor muscles were electr...
#1Masayuki AkatsukaH-Index: 1
#2Hiroomi TatsumiH-Index: 7
Last.Yoshiki MasudaH-Index: 12
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Objective: The purpose of this study was to clarify whether initiation of a rapid response system (RRS) affected the incidence of unplanned intensive care unit (ICU) admissions (UIAs) for treatment of organ dysfunction in the early postoperative period. Methods: We retrospectively identified patients admitted unexpectedly to the ICU from general wards within the first 72 h after surgery between January 2006 and December 2017. Patients with UIAs were divided into two groups: a pre-RRS group (Janu...