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Brian W. Matthews
University of Oregon
Molecular biologyChemistryLysozymeBiochemistryCrystallography
468Publications
95H-index
28.9kCitations
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#1Brian W. Matthews (UO: University of Oregon)H-Index: 95
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#1Brian W. Matthews (UO: University of Oregon)H-Index: 95
Source
#1Brian W. Matthews (UO: University of Oregon)H-Index: 95
Source
#1Brian W. Matthews (UO: University of Oregon)H-Index: 95
2 CitationsSource
1 CitationsSource
Warmest congratulations to Brian Ziemba (right) and Mark Landau (left), the recipients of the Protein Society's “Best Paper” awards. At the beginning of each year, two “best papers” are selected from articles published in Protein Science during the preceding 12 months. A junior author (typically the first author) is designated as the award winner and invited to give a talk at the following Annual Protein Society Symposium. Mark Landau received his Bachelor of Science degree in Chemical Biology f...
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#1Douglas H. Juers (Whitman College)H-Index: 17
#2Brian W. Matthews (UO: University of Oregon)H-Index: 95
Last. Reuben E. Huber (U of C: University of Calgary)H-Index: 23
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This review provides an overview of the structure, function, and catalytic mechanism of lacZ β-galactosidase. The protein played a central role in Jacob and Monod's development of the operon model for the regulation of gene expression. Determination of the crystal structure made it possible to understand why deletion of certain residues toward the amino-terminus not only caused the full enzyme tetramer to dissociate into dimers but also abolished activity. It was also possible to rationalize α-c...
93 CitationsSource
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