Judith A. Ferry
Harvard University
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Publications 232
#1Laila Nomani (Cleveland Clinic)H-Index: 2
#2Claudiu V. Cotta (Cleveland Clinic)H-Index: 10
Last. James R. Cook (Cleveland Clinic)H-Index: 41
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OBJECTIVES: To define the clinicopathologic features of extranodal marginal zone lymphoma (EMZL) of the central nervous system (CNS), including cases arising in CNS parenchyma, which have been reported only rarely. METHODS: Twelve cases of CNS EMZL were identified, including 5 based in CNS parenchyma and 7 nonparenchymal cases arising in dura or choroid plexus. RESULTS: Histologically, parenchymal cases were perivascular infiltrates without a dominant lymphoid mass, whereas nonparenchymal cases ...
#1Bailey Hutchison (Harvard University)
#2Sam Sadigh (Harvard University)
Last. William C. Faquin (Harvard University)H-Index: 48
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Follicular dendritic cell sarcoma (FDCS) is a rare entity which can share morphologic features with non-keratinizing squamous cell carcinoma. Recent reports suggest that up to half of FDCSs show immunohistochemical positivity for p16 (Zhang et al., in Hum Pathol 66:40–47, 2017), a stain that is conventionally used in the risk stratification of oropharyngeal squamous cell carcinoma (OPSCC). Herein, we report a case of p16-positive FDCS with clinical and histomorphologic overlap with human papillo...
#1Rebecca L. King (Mayo Clinic)H-Index: 11
#2John R. GoodladH-Index: 30
Last. Judith A. Ferry (Harvard University)H-Index: 58
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Session 2 of the 2018 European Association of Hematopathology/Society for Hematopathology Workshop focused on lymphomas arising in immune-privileged sites: both lymphomas arising in the traditionally described “immune sanctuary” sites of the central nervous system (CNS) and testes, as well as those arising at sites of local immune privilege. Primary CNS large B cell lymphoma and primary testicular large B cell lymphoma were discussed, and the biology of these unique tumors was highlighted by sev...
2 CitationsSource
#1Ilske OschliesH-Index: 23
#2Rebecca L. King (Mayo Clinic)H-Index: 11
Last. John R. GoodladH-Index: 30
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The major aim of Session 1 of the 2018 European Association of Hematopathology/Society for Hematopathology Workshop was to collect examples of cutaneous lymphomas, excluding mycosis fungoides/Sezary syndrome, as defined in the current WHO classification of tumours of the haemetopoietic and lymphoid tissues. Overall 42 cases were submitted. These were considered in four main categories: primary cutaneous B cell lymphomas (12 cases), primary cutaneous T cell lymphomas/lymphoproliferations with CD8...
1 CitationsSource
#1S. MorenoH-Index: 23
Last. Maria Calaminici (Barts Health NHS Trust)H-Index: 1
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This paper summarizes two sessions of the workshop during the XIX meeting of the European Association for Haematopathology (EAHP) held in Edinburgh in September 2018 dedicated to lymphomas of the gastrointestinal tract. The first session focused on the clinical and pathological features of primary gastrointestinal T cell and NK-cell lymphoproliferative disorders. The distinction between precursor lesions (RCD type 2) and enteropathy-associated T cell lymphoma were stressed, including the discuss...
#1Snjezana Dotlic (University Hospital Centre Zagreb)H-Index: 2
#2Maurilio PonzoniH-Index: 65
Last. Alexandra Traverse-Glehen (University of Lyon)H-Index: 25
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Two sessions in the workshop of the 19th meeting of the European Association for Haematopathology termed “challenging extranodal lymphoproliferations” and “extranodal non-site-specific lymphoproliferations”, dealt with a series of heterogenous cases. These included lymphoproliferations of all cell lineages, from reactive lesions mimicking lymphomas through indolent lymphoid neoplasia and tumours with unclear biological behaviour to aggressive and transformed lymphomas. The themes addressed inclu...
1 CitationsSource
#1Lucas R. Massoth (Harvard University)
#2Yin P. Hung (Harvard University)H-Index: 15
Last. Erik A. Williams (Foundation Medicine)H-Index: 2
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2 CitationsSource
#2Alba NavarroH-Index: 27
Last. Sílvia BeàH-Index: 47
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Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) translocation resulting in overexpression of cyclin D1. However, a small subset of cyclin D1 − MCL has been recognized, and approximately one-half of them harbor CCND2 translocations while the primary event in cyclin D1 − /D2 − MCL remains elusive. To identify other potential mechanisms driving MCL pathogenesis, we investigated 56 cyclin D1 − /SOX11 + MCL by fluorescence in situ hybridization (FISH), whole-genome/exome sequenci...
4 CitationsSource
#1Naema Nayyar (Broad Institute)H-Index: 9
#2Michael D. White (Harvard University)H-Index: 1
Last. Tracy T. Batchelor (Harvard University)H-Index: 73
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The genetic alterations that define primary central nervous system lymphoma (PCNSL) are incompletely elucidated, and the genomic evolution from diagnosis to relapse is poorly understood. We performed whole-exome sequencing (WES) on 36 PCNSL patients and targeted MYD88 sequencing on a validation cohort of 27 PCNSL patients. We also performed WES and phylogenetic analysis of 3 matched newly diagnosed and relapsed tumor specimens and 1 synchronous intracranial and extracranial relapse. Immunohistoc...
1 CitationsSource
#1Daniel Xia (Harvard University)H-Index: 5
#2Elizabeth A. Morgan (Brigham and Women's Hospital)H-Index: 21
Last. Lawrence R. Zukerberg (Harvard University)H-Index: 47
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1 CitationsSource