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Girish Barot
Florida Atlantic University
29Publications
11H-index
283Citations
Publications 29
Newest
Published on Feb 1, 2016in Journal of Macromolecular Science, Part A 1.06
Charles E. Carraher7
Estimated H-index: 7
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
+ 3 AuthorsNandalall Sookdeo3
Estimated H-index: 3
(Florida Atlantic University)
ABSTRACTA wide variety of organotin polyethers derived from the interfacial polymerization of dibutyltin dichloride and non-cancer inhibitory diols show decent to good inhibition of two human pancreatic cancer cell lines. In view of the general lack of ability of tested compounds to inhibit pancreatic cancer cell lines, this is significant. These cell lines are the AsPC-1 pancreatic cancer cell line which is an adenocarcinoma pancreatic cell line and the PANC-1 pancreatic cancer cell line which ...
3 Citations Source Cite
Published on Nov 22, 2015in International Journal of Polymeric Materials 2.13
Charles E. Carraher7
Estimated H-index: 7
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
+ 7 AuthorsZamil Islam1
Estimated H-index: 1
(Florida Atlantic University)
The efforts described in this article are aimed at designing organotin polymers that control the growth of breast cancer and to identify structure/property relationships that assist in this goal. The growth of MCF-7 and MDA-MB-231 breast cancer cell lines is inhibited employing a wide range of organotin condensation polymers. The EC50 values are primarily dependent on the nature of the Lewis base but the CI50 is dependent on both the nature of the Lewis base and Lewis acid. A number of products ...
4 Citations Source Cite
Charles E. Carraher23
Estimated H-index: 23
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
+ 6 AuthorsMohammed H. Al-huniti4
Estimated H-index: 4
(Florida Atlantic University)
The current efforts described in this paper are aimed at developing compounds that inhibit the growth of prostate cancer and to identify structure/property relationships that will further assist us towards this goal. The growth of prostate cancer is affected employing a wide range of organotin condensation polymers. The EC50 values are primarily dependant on the nature of the Lewis base but the CI50 is dependent on both the nature of the Lewis base and Lewis acid. EC50 values down to the picogra...
9 Citations Source Cite
Published on Jan 1, 2014in Journal of Polymer Materials 0.35
Charles E. Carraher23
Estimated H-index: 23
,
Michael R. Roner19
Estimated H-index: 19
+ 3 AuthorsTiasha Arnold1
Estimated H-index: 1
3 Citations
Charles E. Carraher7
Estimated H-index: 7
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
+ 6 AuthorsMohammed H. Al-huniti4
Estimated H-index: 4
(Florida Atlantic University)
The efforts described in this paper are aimed at designing organotin polymers that control the growth of various cancers; here colorectal cancer and to identify structure/property relationships that will assist in this goal. The growth of colorectal cancer is affected employing a wide range of organotin condensation polymers. The EC50 values are primarily dependent on the nature of the Lewis base but the CI50 value is dependent on both the nature of the Lewis base and Lewis acid. EC50 values dow...
Source Cite
Published on Jul 1, 2014in Journal of Polymer Materials 0.35
Charles E. Carraher23
Estimated H-index: 23
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
+ 3 AuthorsTheodore S. Sabir1
Estimated H-index: 1
(Florida Atlantic University)
1 Citations
Published on Apr 1, 2014in Journal of Polymer Materials 0.35
Charles E. Carraher23
Estimated H-index: 23
(Florida Atlantic University),
Michael R. Roner19
Estimated H-index: 19
+ 1 AuthorsKimberly Shahi10
Estimated H-index: 10
(University of Texas at Arlington)
1 Citations
Charles E. Carraher7
Estimated H-index: 7
(Florida Atlantic University),
Girish Barot11
Estimated H-index: 11
(Florida Atlantic University)
+ 1 AuthorsMichael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
The effect of solvent on the ability to inhibit a group of cell lines was studied employing a series of water-soluble dibutyltin polyethers derived from various hydroxyl-terminated poly(ethylene glycols). Molecular weight as a function of time was essentially unchanged for a period of 30 weeks for the polyethers. Variations in test media can affect biological activities on the cell level as well as at the molecular level. The current study involves the evaluation of the cellular effects when dim...
10 Citations Source Cite
Charles E. Carraher7
Estimated H-index: 7
(Florida Atlantic University),
Girish Barot11
Estimated H-index: 11
(Boston University)
+ 2 AuthorsMichael R. Roner19
Estimated H-index: 19
(University of Texas at Arlington)
The degradation of water soluble organotin polyether in the presence of trypsin was studied. The polymer was found to be stable to 4 days, the typical cancer cell line testing time. This is consistent with polymer activity against cancer cell lines being a result of the non-degraded chain and not controlled release of the organotin moiety. As a control trypsin activity was studied employing light scattering photometry and gel electrophoresis. The trypsin was active degrading bovine serine albumi...
12 Citations Source Cite
Published on Jan 1, 2013in Journal of Polymer Materials 0.35
Charles E. Carraher23
Estimated H-index: 23
,
Theodore S. Sabir1
Estimated H-index: 1
(Azusa Pacific University)
+ 1 AuthorsGirish Barot11
Estimated H-index: 11
(Boston University)
123