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Kimio Satoh
Tohoku University
255Publications
28H-index
2,806Citations
Publications 256
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Background Circulating proteins are exposed to vascular endothelial layer and influence their functions. Among them, adipsin is a member of the trypsin family of peptidases and is mainly secreted f...
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Objective: Despite the recent progress in upfront combination therapy for pulmonary arterial hypertension (PAH), useful biomarkers for the disorder still remain to be developed. SeP (Selenoprotein ...
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#1Mina Akizuki (Tohoku University)H-Index: 1
#2Kouichiro Sugimura (Tohoku University)H-Index: 22
Last.Masahiro Kohzuki (Tohoku University)H-Index: 29
view all 10 authors...
Abstract Background Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by organic thrombotic obstructions in the pulmonary arteries with reduced pulmonary vascular reserve. This study aimed to examine whether postural changes in ventilatory gas analysis parameters are useful for assessing pulmonary hemodynamics in patients with CTEPH. Methods A total of 44 patients with newly diagnosed CTEPH (CTEPH group), 33 patients with improved CTEPH (mean pulmonary arterial pressure [mPA...
1 CitationsSource
Patients with adult congenital heart disease (ACHD) are at increased risk of developing late cardiovascular complication. However, little is known about the predictive factors for long-term outcome. The Model for End-Stage Liver Disease eXcluding INR (MELD-XI) score was originally developed to assess cirrhotic patients and has the prognostic value for heart failure (HF) patients. In the present study, we examined whether the score also has the prognostic value in this population. We retrospectiv...
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#1Mohammad Abdul Hai Siddique (Tohoku University)H-Index: 3
#2Kimio Satoh (Tohoku University)H-Index: 28
Last.Hiroaki Shimokawa (Tohoku University)H-Index: 89
view all 13 authors...
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#1Junichi Omura (Tohoku University)H-Index: 9
#2Kimio Satoh (Tohoku University)H-Index: 28
Last.Hiroaki Shimokawa (Tohoku University)H-Index: 89
view all 15 authors...
Rationale: Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling with aberrant pulmonary artery smooth muscle cells (PASMCs) proliferation, endothelial dysfunction...
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#1Junichi OmuraH-Index: 9
#2Kimio SatohH-Index: 28
Last.Hiroaki ShimokawaH-Index: 35
view all 15 authors...
Rationale: Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling with aberrant pulmonary artery smooth muscle cells (PASMCs) proliferation, endothelial dysfunction...
#1Ryo Kurosawa (Tohoku University)H-Index: 10
#2Kimio Satoh (Tohoku University)H-Index: 28
Last.Hiroaki Shimokawa (Tohoku University)H-Index: 89
view all 13 authors...
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#1Katsuya Kozu (Tohoku University)H-Index: 4
#2Kimio Satoh (Tohoku University)H-Index: 28
Last.Hiroaki Shimokawa (Tohoku University)H-Index: 89
view all 18 authors...
Abstract Background Although cardiac troponin and natriuretic peptide have been shown to decrease after balloon pulmonary angioplasty (BPA) with improved right ventricular afterload in chronic thromboembolic pulmonary hypertension (CTEPH), biomarkers to evaluate the effects of BPA independently of heart failure status remain to be developed. Methods In 39 consecutive CTEPH patients including 31 who underwent BPA, we measured plasma levels of cyclophilin A (CyPA), which we demonstrated is secrete...
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#1Nobuhiro Kikuchi (Tohoku University)H-Index: 9
#2Kimio Satoh (Tohoku University)H-Index: 28
Last.Hiroaki Shimokawa (Tohoku University)H-Index: 89
view all 12 authors...
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