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Moon-Moo Kim
Dong-eui University
119Publications
28H-index
2,401Citations
Publications 119
Newest
Published on Apr 1, 2019in Molecular Biology Reports2.11
Hyeju Ko (Dong-eui University), Moon-Moo Kim28
Estimated H-index: 28
(Dong-eui University)
The purpose of this study is to investigate the effect of H2O2 on the aging of melanogenesis in human melanocytes. The staining of SA-β-galactosidase, an aging marker, was remarkably increased in the cells aged with H2O2 at 62.5 µM or more compared with young cells. The intracellular H2O2 level and melanin synthesis were also reduced in both H2O2-treated cells and senescent cells compared with young cells in DCFH-DA assay. Both the senescent cells and the H2O2-treated cells showed higher express...
Published on Apr 1, 2018in Environmental Toxicology and Pharmacology3.06
Sugyeong Hong2
Estimated H-index: 2
(Dong-eui University),
Moon-Moo Kim28
Estimated H-index: 28
(Dong-eui University)
Abstract Aging study requires aging markers to measure the degree of aging process. The aging markers such as senescence associated-β-galactosidase (SA-β-gal), lipofuscin, telomere, p53 and p16 have been known in aging study until now. Therefore, we investigated the role of genes and proteins related to aging in young, senescent and H 2 O 2 -induced old cells to develop a novel aging marker involved in aging mechanism. After cellular aging was compared in young, senescent and H 2 O 2 -induced ol...
Published on Dec 1, 2017in Phytomedicine4.18
Su-Gyeong Lee1
Estimated H-index: 1
(Dong-eui University),
Moon-Moo Kim28
Estimated H-index: 28
(Dong-eui University)
Abstract Background The insulin-like growth factor 1 (IGF-1) signaling pathway has spotlighted as a mechanism to elucidate aging associated with autophagy in recent years. Therefore, we have tried to screen an effective compound capable of inducing autophagy to delay aging process. Purpose The aim of this study is to investigate whether pachymic acid, a main compound in Poria cocos, induces autophagy in the aged cells. Methods The aging of young cells was induced by treatment with IGF-1 at 50 ng...
Published on Jan 1, 2017in Environmental Toxicology and Pharmacology3.06
Eun-Jeong Kwon1
Estimated H-index: 1
(Dong-eui University),
Moon-Moo Kim28
Estimated H-index: 28
(Dong-eui University)
Abstract Agmatine contained in soybean is also found in Manaca, an anti-aging plant, inhabited in Amazon and induces vasodilation by the promotion of NO synthesis in blood vessel. However, the research of agmatine on melanin synthesis related to hair greying is lacking. The aim of this study was to investigate the melanogenic effect of agmatine via regulation of MITF signaling pathway in B16F1 cells. It was determined whether agmatine regulates melanin synthesis at cellular level in addition to ...
Published on Nov 30, 2016
Min Woo Kim , Hyun Jin Kim32
Estimated H-index: 32
+ 4 AuthorsHyun-Tai Lee2
Estimated H-index: 2
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