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Sara Jane Webb
University of Washington
80Publications
30H-index
5,407Citations
Publications 80
Newest
Published on Jun 1, 2019in Biological Psychology 2.63
Maura Sabatos-DeVito8
Estimated H-index: 8
(Duke University),
Michael Murias15
Estimated H-index: 15
(Duke University)
+ 15 AuthorsJames Dzuira (Yale University)
Abstract Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms desi...
Published on May 1, 2019in Autism Research 3.70
David G. Amaral98
Estimated H-index: 98
,
George M. Anderson60
Estimated H-index: 60
+ 28 AuthorsPetrus J. de Vries15
Estimated H-index: 15
Published on Jan 1, 2019in Autism Research 3.70
Tessel Bazelmans1
Estimated H-index: 1
('KCL': King's College London),
Emily J.H. Jones23
Estimated H-index: 23
(Birkbeck, University of London)
+ 4 AuthorsSara Jane Webb30
Estimated H-index: 30
(Seattle Children's Research Institute)
Interest in autonomic arousal in autism spectrum disorder (ASD) is increasing; however, reliability of these measures in ASD is unknown, and previously reported associations with social and cognitive abilities are inconsistent. This study assesses heart rate (HR) and HR variability (HRV) in preschoolers with ASD or typical development (TD) while they passively watched naturalistic videos. Measurement reliability, group differences, and the relationship with social and cognitive abilities were ev...
Published on Dec 1, 2018in Journal of Neurodevelopmental Disorders 3.59
Sandra Naumann1
Estimated H-index: 1
(Humboldt University of Berlin),
Ulrike Senftleben1
Estimated H-index: 1
(TUD: Dresden University of Technology)
+ 2 AuthorsSara Jane Webb30
Estimated H-index: 30
(UW: University of Washington)
Background Face processing has been found to be impaired in autism spectrum disorders (ASD). One hypothesis is that individuals with ASD engage in piecemeal compared to holistic face processing strategies. To investigate the role of possible impairments in holistic face processing in individuals with autism, the current study investigated behavioral and electroencephalography (EEG) correlates of face processing (P1/N170 and gamma-band activity) in adolescents with ASD and sex-, age-, and IQ-matc...
Published on Dec 1, 2018in Brain and Language 2.70
Anne B. Arnett8
Estimated H-index: 8
(UW: University of Washington),
Caitlin M. Hudac11
Estimated H-index: 11
(UW: University of Washington)
+ 5 AuthorsSara Jane Webb30
Estimated H-index: 30
(UW: University of Washington)
Abstract Background Autism spectrum disorder (ASD) is associated with language impairment as well as atypical auditory sensory processing. The current study investigated associations among auditory perception, implicit language learning and receptive language ability in youth with ASD. Methods We measured auditory event related potentials (ERP) during an artificial language statistical learning task in 76 youth with ASD and 27 neurotypical (NT) controls. Participants with ASD had a broad range o...
Published on Oct 22, 2018in Frontiers in Psychiatry 3.16
Emily Neuhaus12
Estimated H-index: 12
(Seattle Children's Research Institute),
Raphael Bernier38
Estimated H-index: 38
(UW: University of Washington)
+ 1 AuthorsSara Jane Webb30
Estimated H-index: 30
(Seattle Children's Research Institute)
Individuals with autism spectrum disorder (ASD) are at heightened risk of psychiatric comorbidities across the lifespan, including elevated rates of internalizing, externalizing, and self-injurious behaviors. Identification of medical comorbidities that contribute to these concerns may elucidate mechanisms through which psychiatric concerns arise, as well as offer additional avenues for intervention. Gastrointestinal (GI) conditions are of particular interest, as they are prevalent among those w...
Published on Oct 1, 2018in Human Genetics 5.21
Nicola H. Chapman14
Estimated H-index: 14
(UW: University of Washington),
Raphael Bernier38
Estimated H-index: 38
(UW: University of Washington)
+ 6 AuthorsEllen M. Wijsman61
Estimated H-index: 61
(UW: University of Washington)
Hundreds of genes have been implicated in autism spectrum disorders (ASDs). In genetically heterogeneous conditions, large families with multiple affected individuals provide strong evidence implicating a rare variant, and replication of the same variant in multiple families is unusual. We previously published linkage analyses and follow-up exome sequencing in seven large families with ASDs, implicating 14 rare exome variants. These included rs200195897, which was transmitted to four affected in...
Published on Jun 1, 2018in Brain and Cognition 2.62
Caitlin M. Hudac11
Estimated H-index: 11
(UW: University of Washington),
Trent D. DesChamps3
Estimated H-index: 3
(UW: University of Washington)
+ 4 AuthorsRaphael Bernier38
Estimated H-index: 38
(UW: University of Washington)
Abstract Children with autism spectrum disorder (ASD) exhibit difficulties processing and encoding sensory information in daily life. Cognitive response to environmental change in control individuals is naturally dynamic, meaning it habituates or reduces over time as one becomes accustomed to the deviance. The origin of atypical response to deviance in ASD may relate to differences in this dynamic habituation. The current study of 133 children and young adults with and without ASD examined class...
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