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Alva Engell
University of Münster
12Publications
6H-index
102Citations
Publications 12
Newest
#1Katja Koelkebeck (WWU: University of Münster)H-Index: 13
#2Lisa Kuegler (WWU: University of Münster)H-Index: 1
Last.Rebekka Lencer (WWU: University of Münster)H-Index: 18
view all 5 authors...
Abstract Background Patients with schizophrenia have difficulties in several aspects of social cognition, e.g. emotion recognition and mentalizing. It is yet unclear if patients also show deficits in moral decision-making and whether the two aspects interact. Deficits in moral decision-making abilities might put patients in disadvantageous positions in every-day interactions. Method Twenty-five patients with schizophrenia and twenty-five matched healthy controls participated in six moral dilemma...
1 CitationsSource
#1Pia LauH-Index: 6
#2Andreas WollbrinkH-Index: 15
Last.Christo PantevH-Index: 62
view all 7 authors...
Abstract Tinnitus is a prevalent phenomenon and bothersome for people affected by it. Its occurrence and maintenance have a clear neuroscientific tie and one aspect are differences in the neuronal oscillatory pattern, especially in auditory cortical areas. As studies in this field come to different results, the aim of this study was to analyze a large number of participants to achieve more stable results. Furthermore, we expanded our analysis to two variables of potential influence, namely being...
1 CitationsSource
#1Alwina Stein (WWU: University of Münster)H-Index: 6
#2Robert Wunderlich (WWU: University of Münster)H-Index: 6
Last.Christo Pantev (WWU: University of Münster)H-Index: 62
view all 10 authors...
Background Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed due to synchronous mass activity owing to the lack of inhibition. We assume that removal of exactly these frequencies from a complex auditory stimulus will cause the brain to reorganize around tonotopic regions coding the tinnitus frequency through inhibition-induced plasticity. Based on this assumption, a novel treatment for tonal tinnitus - tailor-made notche...
32 CitationsSource
#1Alva EngellH-Index: 6
#2Markus JunghöferH-Index: 35
Last.Christo PantevH-Index: 62
view all 7 authors...
Reduced neural processing of a tone is observed when it is presented after a sound whose spectral range closely frames the frequency of the tone. This observation might be explained by the mechanism of lateral inhibition (LI) due to inhibitory interneurons in the auditory system. So far, several characteristics of bottom up influences on LI have been identified, while the influence of top-down processes such as directed attention on LI has not been investigated. Hence, the study at hand aims at ...
5 CitationsSource
#1Robert WunderlichH-Index: 6
#2Pia LauH-Index: 6
Last.Christo PantevH-Index: 62
view all 7 authors...
Tinnitus, the ringing in the ears that is unrelated to any external source, causes a significant loss in quality of life, involving sleep disturbance and depression for 1 to 3% of the general population. While in the first place tinnitus may be triggered by damage to the inner ear cells, the neural generators of subjective tinnitus are located in central regions of the nervous system. A loss of lateral inhibition, tonotopical reorganization and a gain-increase in response to the sensory deprivat...
15 CitationsSource
#1Alwina Stein (WWU: University of Münster)H-Index: 6
#2Alva Engell (WWU: University of Münster)H-Index: 6
Last.Christo Pantev (WWU: University of Münster)H-Index: 62
view all 9 authors...
Chronic tinnitus seems to be caused by reduced inhibition among frequency selective neurons in the auditory cortex. One possibility to reduce tinnitus perception is to induce inhibition onto over-activated neurons representing the tinnitus frequency via tailor-made notched music (TMNM). Since lateral inhibition is modifiable by spectral energy contrasts, the question arises if the effects of inhibition-induced plasticity can be enhanced by introducing increased spectral energy contrasts (ISEC) i...
5 CitationsSource
#1Alwina Stein (WWU: University of Münster)H-Index: 6
#2Alva Engell (WWU: University of Münster)H-Index: 6
Last.Christo Pantev (WWU: University of Münster)H-Index: 62
view all 8 authors...
Abstract Objective Notch-filtered music has been shown to induce frequency-specific inhibition. Here, we investigated which cortical structures are affected by tailor-made notched music (TMNM) in tinnitus patients and how this inhibition-induced plasticity develops over time. Methods Nine subjects suffering from chronic tonal tinnitus listened to music passing through a notch-filter centered at the patient’s individual tinnitus frequency (TMNM) for three hours on three consecutive days. Before a...
9 CitationsSource
9 CitationsSource
#1Pia LauH-Index: 6
#2Miriam MiesenH-Index: 1
Last.Christo Pantev (WWU: University of Münster)H-Index: 62
view all 10 authors...
In order to better understand tinnitus and distress associated with tinnitus, psychological variables such as emotional and cognitive processing are a central element in theoretical models of this debilitating condition. Interoception, that is, the perception of internal processes, may be such a psychological factor relevant to tinnitus. Against this background, 20 participants suffering from chronic tinnitus and 20 matched healthy controls were tested with questionnaires, assessing interoceptiv...
8 CitationsSource
#1Christo Pantev (WWU: University of Münster)H-Index: 62
#2Claudia Rudack (WWU: University of Münster)H-Index: 18
Last.Alex ShaykevichH-Index: 3
view all 8 authors...
Background Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed to synchronous mass activity owing the lack of inhibition. We assume that removal of exactly these frequency components from an auditory stimulus will cause the brain to reorganize around tonotopic regions coding the tinnitus frequency. Based on this assumption a novel treatment for tonal tinnitus - tailor-made notched music training (TMNMT) (Proc Natl Acad Sci...
6 CitationsSource
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