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Sara-Ann Legrand
Ghent University
29Publications
11H-index
430Citations
Publications 29
Newest
#1Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
#2Hallvard Gjerde (FHI: Norwegian Institute of Public Health)H-Index: 24
Last.Alain Verstraete (UGent: Ghent University)H-Index: 33
view all 9 authors...
Our objective was to determine the presence of psychoactive substances in blood of drivers killed in road crashes in four European countries. Data from 1118 drivers of car and vans, killed between 2006 and 2009, were collected in Finland, Norway, Portugal and Sweden. The prevalence of any psychoactive substance ranged between 31 and 48%. Alcohol (>= 0.1 g/L) was the most common finding, 87% had a blood alcohol concentration (BAC)>=.5 g/L. Benzodiazepines (1.8-13.3%) and amphetamines (0-7.4%) wer...
15 CitationsSource
#1Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
#2Peter SilveransH-Index: 3
Last.Alain Verstraete (UGent: Ghent University)H-Index: 33
view all 5 authors...
Objective: To estimate the percentage of drivers involved in a traffic crash in Belgium who have alcohol and drugs in their blood. Methods: Blood samples of the drivers injured in a traffic crash and admitted to the emergency departments of 5 hospitals in Belgium between January 2008 and May 2010 were analyzed for ethanol (with an enzymatic method) and 22 other psychoactive substances (with ultra-performance liquid chromatography with tandem mass spectrometry or gas chromatography–mass spectrome...
11 CitationsSource
#1Trudy Van der Linden (UGent: Ghent University)H-Index: 9
#2Cristina Isalberti (UGent: Ghent University)H-Index: 5
Last.Alain Verstraete (UGent: Ghent University)H-Index: 33
view all 5 authors...
The objective of this paper is to compare concentrations of alcohol, illicit, and medicinal drugs in seriously injured drivers and drivers selected randomly at the roadside. Blood samples were analyzed for alcohol, 17 medicinal drugs and 8 illicit psychoactive substances and/or their metabolites by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and gas chromatography mass spectrometry (GC-MS) in injured drivers admitted to the emergency departments of five hospital...
2 CitationsSource
#1Sjoerd HouwingH-Index: 12
#2Marjan HagenziekerH-Index: 15
Last.Karel Brookhuis (UG: University of Groningen)H-Index: 40
view all 14 authors...
Between 2006 and 2010, six population based case-control studies were conducted as part of the European research-project DRUID (DRiving Under the Influence of Drugs, alcohol and medicines). The aim of these case-control studies was to calculate odds ratios indicating the relative risk of serious injury in car crashes. The calculated odds ratios in these studies showed large variations, despite the use of uniform guidelines for the study designs. The main objective of the present article is to pr...
13 CitationsSource
#1Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
#2Cristina Isalberti (UGent: Ghent University)H-Index: 5
Last.Alain Verstraete (UGent: Ghent University)H-Index: 33
view all 17 authors...
The objective of this study was to determine the presence of alcohol and drugs in drivers severely injured in traffic crashes in six European countries. Data were collected from 2492 seriously injured drivers of cars and vans in Belgium, Denmark, Finland, Italy, Lithuania, and the Netherlands, between 2007 and 2010. Toxicological analysis was performed with chromatographic techniques on whole blood for 23 substances. The percentage of drivers positive for at least one psychoactive substance rang...
33 CitationsSource
#1Alain Verstraete (UGent: Ghent University)H-Index: 33
#2Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
Driving is a complex task. Psychoactive substances are found in 1–10% of the general driving population, in 19–50% of injured or killed drivers, and in 55–99% of drivers who are suspected of driving under the influence of drugs (DUID). Drivers who are under the influence of drugs have a higher risk of being involved in or being responsible for an accident. Two major types of DUID legislation exist: ‘impairment’ and ‘per se’ legislation. For the detection of drugged drivers, checklists have been ...
2 CitationsSource
#1Sjoerd HouwingH-Index: 12
#2Sara-Ann LegrandH-Index: 11
Last.Karel BrookhuisH-Index: 40
view all 6 authors...
#1Sjoerd HouwingH-Index: 12
#2Beitske E. Smink (Netherlands Forensic Institute)H-Index: 11
Last.Karel Brookhuis (UG: University of Groningen)H-Index: 40
view all 6 authors...
Abstract Study objectives To determine the influence of sample collection for two different collection methods on THC concentrations and to compare THC concentrations collected by both methods. Methods A total of 136 pairs of oral fluid samples from subjects who had recently smoked Cannabis were obtained by the non-acidic Statsure oral fluid collection device and by ordinary spit tubes. Oral fluid was analyzed for THC by LC–MS/MS. Bland–Altman plots were used for the quantitative analysis of rep...
11 CitationsSource
#1Sjoerd HouwingH-Index: 12
#2Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
Last.Karel BrookhuisH-Index: 40
view all 6 authors...
Objective:The purpose of this study was to compare the prevalence of psychoactive substances in general traffic in The Netherlands and Belgium.Method:Randomly selected car drivers and drivers of small vans in six police regions in The Netherlands and five police regions in Belgium were included between January 2007 and August 2009. Blood and oral fluid samples were analyzed for 23 substances, including ethanol (alcohol), by means of ultra performance liquid chromatography–tandem mass spectrometr...
10 CitationsSource
#1Kim P. C. Kuypers (UGent: Ghent University)H-Index: 21
#2Sara-Ann Legrand (UGent: Ghent University)H-Index: 11
Last.Alain Verstraete (UGent: Ghent University)H-Index: 33
view all 4 authors...
BACKGROUND: The aim of the present study was to assess the risk of having a traffic accident after using alcohol, single drugs, or a combination, and to determine the concentrations at which this risk is significantly increased. METHODS: A population-based case-control study was carried out, collecting whole blood samples of both cases and controls, in which a number of drugs were detected. The risk of having an accident when under the influence of drugs was estimated using logistic regression a...
54 CitationsSource
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