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Sonja Y. Hess
University of California, Davis
EndocrinologyMicronutrientPopulationZincMedicine
96Publications
28H-index
2,844Citations
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Publications 96
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#1Guy-Marino Hinnouho (UC Davis: University of California, Davis)H-Index: 6
#1Guy-Marino Hinnouho (Helen Keller International)
Last. Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
view all 7 authors...
The objective of this study was to assess the impact of different strategies for delivering supplemental zinc on fecal myeloperoxidase (MPO), neopterin (NEO), and calprotectin (CAL) among young Laotian children. In a double-blind controlled trial, children aged 6-23 months were randomized to receive either daily preventive zinc (PZ) tablets (7 mg/day), daily micronutrient powder (MNP; containing 10 mg zinc and 14 other micronutrients), therapeutic zinc (TZ) supplements for diarrhea treatment (20...
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#1Maxwell A. Barffour (UC Davis: University of California, Davis)H-Index: 6
#2Guy-Marino Hinnouho (UC Davis: University of California, Davis)H-Index: 6
Last. Charles D Arnold (UC Davis: University of California, Davis)H-Index: 6
view all 13 authors...
Background Diarrhea and respiratory tract infections are leading causes of childhood morbidity and mortality. This individually randomized, double-blind placebo-controlled trial was designed to evaluate the effects of different zinc supplementation regimens on the incidence and duration of diarrhea and acute lower (ALRI) and upper (AURI) respiratory tract infections among rural Laotian children. The study included 3407 children, 6-23 months at enrollment. Methods Children were randomized to one ...
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#1K. Ryan Wessells (UC Davis: University of California, Davis)H-Index: 13
#2Kenneth H. Brown (UC Davis: University of California, Davis)H-Index: 67
Last. Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
view all 8 authors...
Plasma zinc concentrations (PZC) have been shown to significantly increase during zinc supplementation. This study investigated the effects of daily preventive zinc supplementation on hair and nail zinc concentrations compared with a control group. In a randomized controlled trial, 6- to 23-month-old children (n = 3407) in Lao PDR were randomly assigned to one of four groups and followed for ~ 36 weeks: daily preventive zinc dispersible tablet (7 mg/d; PZ), daily micronutrient powder (10 mg zinc...
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#1Christine McDonald (Children's Hospital Oakland Research Institute)H-Index: 35
#1Christine M McDonald (Children's Hospital Oakland Research Institute)H-Index: 1
Last. Kenneth H. Brown (UC Davis: University of California, Davis)H-Index: 67
view all 11 authors...
BACKGROUND: The accurate estimation of zinc deficiency at the population level is important, as it guides the design, targeting, and evaluation of nutrition interventions. Plasma or serum zinc concentration (PZC) is recommended to estimate zinc nutritional status; however, concentrations may decrease in the presence of inflammation. OBJECTIVES: We aimed to assess the relation between PZC and inflammation in preschool children (PSC; 6-59 mo) and nonpregnant women of reproductive age (WRA; 15-49 y...
1 CitationsSource
#1Chidchamai Kewcharoenwong (KKU: Khon Kaen University)H-Index: 8
#2Gertrud U. Schuster (UC Davis: University of California, Davis)H-Index: 19
Last. Inthira Tussakhon (KKU: Khon Kaen University)H-Index: 1
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BACKGROUND: Zinc deficiency impairs immune function and is common among children in South-East Asia. OBJECTIVES: The effect of zinc supplementation on immune function in young Laotian children was investigated. METHODS: Children (n = 512) aged 6-23 mo received daily preventive zinc tablets (PZ; 7 mg Zn/d), daily multiple micronutrient powder (MNP; 10 mg Zn/d, 6 mg Fe/d, plus 13 other micronutrients), therapeutic dispersible zinc tablets only in association with diarrhea episodes (TZ; 20 mg Zn/d ...
1 CitationsSource
#1Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
#2Taryn J Smith (UC Davis: University of California, Davis)
Last. Jay Yeh (UC Davis: University of California, Davis)
view all 15 authors...
Introduction Diagnosis of infantile thiamine deficiency disorders (TDD) is challenging due to the non-specific, highly variable clinical presentation, often leading to misdiagnosis. Our primary objective is to develop a case definition for thiamine responsive disorders (TRD) to determine among hospitalised infants and young children, which clinical features and risk factors identify those who respond positively to thiamine administration. Methods and analysis This prospective study will enrol 66...
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#1Benchawan Kingchaiyaphum (KKU: Khon Kaen University)H-Index: 1
#2Kanokwan Sanchaisuriya (KKU: Khon Kaen University)H-Index: 27
Last. Supan Fucharoen (KKU: Khon Kaen University)H-Index: 35
view all 10 authors...
INTRODUCTION: Determination of hemoglobins (Hbs) F, A2, and E is crucial for diagnosis of thalassemia. This study determined the levels of Hbs F, A2, and E in children aged 6-23 months and investigated the effect of age, sex, and types of thalassemia on the expression of these Hbs. METHODS: A total of 698 blood samples of Laotian children including 272 non-Hb E, 271 Hb E heterozygotes, and 155 Hb E homozygotes were collected. Hb profiles were determined using the capillary zone electrophoresis. ...
1 CitationsSource
#1K. Wessells (UC Davis: University of California, Davis)H-Index: 1
#1Wessells Kr (UC Davis: University of California, Davis)
Last. Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
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Environmental enteric dysfunction (EED) may be ameliorated by zinc supplementation. The objective of this study was to investigate the impact of different forms of zinc supplementation on biomarkers of EED (i.e., plasma citrulline, kynurenine, and tryptophan concentrations and the kynurenine:tryptophan [KT] ratio) among young Laotian children. In a double-blind randomized controlled trial, 3,407 children aged 6-23 months were randomized into one of four groups: daily preventive zinc dispersible ...
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#1Césaire T. Ouédraogo (UC Davis: University of California, Davis)H-Index: 6
#2K. Ryan Wessells (UC Davis: University of California, Davis)H-Index: 13
Last. Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
view all 5 authors...
: Low gestational weight gain (GWG) and low mid-upper arm circumference (MUAC) are associated with adverse pregnancy outcomes. We aimed to assess the prevalence and determinants of low GWG and low MUAC among pregnant women in rural Zinder, Niger. A community-based survey was conducted among 1,384 pregnant women in the catchment areas of 18 integrated health centers in the region of Zinder, Niger. Weight and MUAC were measured during an in-home visit and again 1 month later, when haemoglobin conc...
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#1Césaire T. Ouédraogo (UC Davis: University of California, Davis)H-Index: 6
#2K. Ryan Wessells (UC Davis: University of California, Davis)H-Index: 13
Last. Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 28
view all 7 authors...
Background Anaemia is prevalent among pregnant women in rural Niger and antenatal care (ANC) attendance is suboptimal. We designed a programmatic intervention including community-based behaviour change communication, provision of essential drugs (including iron folic acid (IFA) supplements) and quality improvement activities at selected integrated health centres (IHCs). Objective To assess the impact of the programmatic intervention on: (1) utilisation of ANC, (2) adherence to daily IFA suppleme...
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