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Gilberto Vargas-Alarcón
Grupo México
AllelePopulationGeneticsMedicineBiology
341Publications
33H-index
4,207Citations
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Publications 341
Newest
#1Antonio Arnaiz-Villena (Complutense University of Madrid)H-Index: 40
#2Ignacio Juarez (Complutense University of Madrid)H-Index: 2
Last. Gilberto Vargas-AlarcónH-Index: 33
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Abstract Huastecos or Teenek Amerindians are presently living at North East Mexico (San Luis Potosi State). They have probably one of the most ancient culture of Mexico and Central America together with Mayas and Olmec groups with which also show close relationships. Proximity to Atlantic Ocean/Mexican Gulf originated that Spaniards had very early contact with them at about 1519 CE or before. In the present paper we have aimed to study HLA gene profile which may be useful for HLA and disease epi...
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#1Antonio Arnaiz-Villena (Complutense University of Madrid)H-Index: 40
#2Ignacio Juarez (Complutense University of Madrid)H-Index: 2
Last. Fabio Suarez-Trujillo (Complutense University of Madrid)
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Abstract Mexican Mayo Amerindians live in southern Sonora and North Sinaloa states. They probably come from North or are related to First American Inhabitants established further North. A non-related sample of them have volunteered to HLA study in order to achieve a profile useful for their epidemiology and future transplant interstate programs, in addition to ascertain ancestry and anthropological studies. HLA typing was carried out by a standard methodology. HLA-B*48 allele(s) was found, which...
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Last. José Manuel FragosoH-Index: 3
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Last. José Manuel FragosoH-Index: 3
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Recent studies have shown that P-selectin promotes the early formation of atherosclerotic plaque. The aim of the present study was to evaluate whether the SELP gene single nucleotide polymorphisms (SNPs) are associated with presence of acute coronary syndrome (ACS) and with plasma P-selectin levels in a case-control association study. The sample size was estimated for a statistical power of 80%. We genotyped three SELP (SELP Ser290Asn, SELP Leu599Val, and SELP Thr715Pro) SNPs using 5’ exonucleas...
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Introduction Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder for which Major Histocompatibility Complex (MHC) genes are well-identified as risk factors. SLE patients have different phenotypes or clinical presentations, which vary among Mexicans. This variation could be explained by ethnicity and admixture. Since socioeconomic status probably limits and change the patterns of migration, this factor could favor inbreeding and homogamy in some geographic areas. Consequentl...
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Last. Gilberto Vargas-AlarcónH-Index: 33
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Inflammation has been involved in the development of atherosclerosis, type 2 diabetes mellitus, insulin resistance, and obesity. Interleukin 20 is a pro-inflammatory cytokine encoded by a polymorphic gene located in chromosome 1. The aim of the study was to evaluate the association of two IL-20 polymorphisms (rs1400986 and rs1518108) with subclinical atherosclerosis (SA), cardiovascular risk factors and IL-20 levels in a cohort of Mexican individuals. The polymorphisms were determined in 274 ind...
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Last. José Manuel FragosoH-Index: 13
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#1Thelma Beatriz González-Castro (UJAT: Universidad Juárez Autónoma de Tabasco)H-Index: 9
#2Ruben Blachman-Braun (UM: University of Miami)H-Index: 1
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Abstract Nephrolithiasis is a complex disease in which its pathophysiology is strongly influenced by genetics. Polymorphisms of the vitamin D receptor ( VDR ) gene have been reported to be associated with the development of kidney stones which in most cases are composed predominantly of calcium salts. For the purpose of this study, we performed a systematic review and meta-analysis to analyze the association of BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236) and FokI (rs2228570) polymorphism...
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