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Arhat Abzhanov
Harvard University
39Publications
22H-index
2,436Citations
Publications 39
Newest
#1Jasmin Camacho (Harvard University)H-Index: 8
#2Alexander Heyde (Harvard University)H-Index: 2
Last.Arhat Abzhanov (Harvard University)H-Index: 22
view all 6 authors...
#1Zachary S. Morris (Harvard University)H-Index: 11
#2Kent A. Vliet (UF: University of Florida)H-Index: 18
Last.Stephanie E. Pierce (Harvard University)H-Index: 15
view all 4 authors...
The distinctive anatomy of the crocodylian skull is intimately linked with dietary ecology, resulting in repeated convergence on blunt- and slender-snouted ecomorphs. These evolutionary shifts depe...
#1Arhat Abzhanov (Imperial College London)H-Index: 22
In 1917, the publication of On Growth and Form by D9Arcy Wentworth Thompson challenged both mathematicians and naturalists to think about biological shapes and diversity as more than a confusion of chaotic forms generated at random, but rather as geometric shapes that could be described by principles of physics and mathematics. Thompson9s work was based on the ideas of Galileo and Goethe on morphology and of Russell on functionalism, but he was first to postulate that physical forces and interna...
#1Matteo Fabbri (AMNH: American Museum of Natural History)H-Index: 7
#2Nicolás Mongiardino Koch (AMNH: American Museum of Natural History)H-Index: 6
Last.Bhart-Anjan S. Bhullar (AMNH: American Museum of Natural History)H-Index: 16
view all 15 authors...
Major transformations in brain size and proportions, such as the enlargement of the brain during the evolution of birds, are accompanied by profound modifications to the skull roof. However, the hypothesis of concerted evolution of shape between brain and skull roof over major phylogenetic transitions, and in particular of an ontogenetic relationship between specific regions of the brain and the skull roof, has never been formally tested. We performed 3D morphometric analyses to examine the deep...
#1Masayoshi Tokita (Harvard University)H-Index: 15
#2Wataru Yano (Asahi University)H-Index: 5
Last.Arhat Abzhanov (Harvard University)H-Index: 22
view all 4 authors...
Adaptive radiation is the rapid evolution of morphologically and ecologically diverse species from a single ancestor. The two classic examples of adaptive radiation are Darwin's finches and the Haw...
#1Bumjin Namkoong (Harvard University)H-Index: 2
#2Sinan Güven (Stanford University)H-Index: 19
Last.Utkan Demirci (Stanford University)H-Index: 56
view all 6 authors...
The experimental systems that recapitulate the complexity of native tissues and enable precise control over the microenvironment are becoming essential for the pre-clinical tests of therapeutics and tissue engineering. Here, we described a strategy to develop an in vitro platform to study the developmental biology of craniofacial osteogenesis. In this study, we directly osteo-differentiated cranial neural crest cells (CNCCs) in a 3-D in vitro bioengineered microenvironment. Cells were encapsulat...
#2Zachary S. Morris (Harvard University)H-Index: 11
Last.Arhat Abzhanov (Imperial College London)H-Index: 22
view all 9 authors...
The avian beak is a key evolutionary innovation whose flexibility has permitted birds to diversify into a range of disparate ecological niches. We approached the problem of the mechanism behind this innovation using an approach bridging paleontology, comparative anatomy, and experimental developmental biology. First, we used fossil and extant data to show the beak is distinctive in consisting of fused premaxillae that are geometrically distinct from those of ancestral archosaurs. To elucidate un...
#1Joerg A. Fritz (Harvard University)H-Index: 3
#2Joseph Brancale (Harvard University)H-Index: 2
Last.Michael P. Brenner (Harvard University)H-Index: 58
view all 7 authors...
The striking diversity of bird beak shapes is an outcome of natural selection, yet the relative importance of the limitations imposed by the process of beak development on generating such variation is unclear. Untangling these factors requires mapping developmental mechanisms over a phylogeny far exceeding model systems studied thus far. We address this issue with a comparative morphometric analysis of beak shape in a diverse group of songbirds. Here we show that the dynamics of the proliferativ...
#1Thomas J. Sanger (Harvard University)H-Index: 17
#2Susan M. Seav (Harvard University)H-Index: 4
Last.Arhat Abzhanov (Harvard University)H-Index: 22
view all 7 authors...
Sexual dimorphisms vary widely among species. This variation must arise through sex-specific evolutionary modifications to developmental processes. Anolis lizards vary extensively in their expression of cranial dimorphism. Compared with other Anolis species, members of the carolinensis clade have evolved relatively high levels of cranial dimorphism; males of this clade have exceptionally long faces relative to conspecific females. Developmentally, this facial length dimorphism arises through an ...
#1Arhat Abzhanov (Harvard University)H-Index: 22
In 1828, Karl Ernst von Baer formulated a series of empirically defined rules, which became widely known as the ‘Law of Development’ or ‘von Baer’s law of embryology’. This was one the most significant attempts to define the principles that connected morphological complexity and embryonic development. Understanding this relation is central to both evolutionary biology and developmental genetics. Von Baer’s ideas have been both a source of inspiration to generations of biologists and a target of ...
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