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Muhammad Shaalan Beg
University of Texas Southwestern Medical Center
CancerPathologyOncologyColorectal cancerMedicine
154Publications
14H-index
1,013Citations
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Publications 153
Newest
#1Colin Bergstrom (UTSW: University of Texas Southwestern Medical Center)H-Index: 1
#2Muhammad Shaalan Beg (UTSW: University of Texas Southwestern Medical Center)H-Index: 14
Last. Ian J. Neeland (UTSW: University of Texas Southwestern Medical Center)H-Index: 25
view all 5 authors...
Background: Lymphotoxin-beta receptor (LTbetaR) is an immunological protein associated with inflammation, and from preclinical studies is implicated in tumorigenesis. The epidemiological relationships with cancer are unknown, hence this study investigated their associations. Methods: From a multiethnic population-based cohort, 3,032 participants without a prevalent cancer (a diagnosis prior to or within one year of enrollment) at baseline underwent measurement of plasma LTbetaR. These participan...
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#1David Hsiehchen (UTSW: University of Texas Southwestern Medical Center)H-Index: 4
#2Antony Hsieh (UPenn: University of Pennsylvania)H-Index: 4
Last. Hao Zhu (UTSW: University of Texas Southwestern Medical Center)H-Index: 25
view all 9 authors...
Summary Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, but prediction of their benefit is challenging. Neoantigens generated through impaired non-mismatch DNA repair may result in greater ICI activity. By analyzing 1,661 ICI-treated patients, we show that deletions and mutations in nucleotide excision repair (NER) and homologous repair (HR) pathways are predictors of ICI benefit independent of tumor mutation burden and tumor type. NER and HR mutations are also associated...
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#1Syed Mohammad Ali Kazmi (UTSW: University of Texas Southwestern Medical Center)
#2Suleyman Yasin Goksu (UTSW: University of Texas Southwestern Medical Center)
Last. Aravind Sanjeevaiah (UTSW: University of Texas Southwestern Medical Center)H-Index: 5
view all 13 authors...
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#1Udhayvir Singh Grewal (LSU Health Sciences Center Shreveport)
Last. Muhammad Shaalan Beg (UTSW: University of Texas Southwestern Medical Center)H-Index: 14
view all 8 authors...
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#1Nina N. Sanford (UTSW: University of Texas Southwestern Medical Center)H-Index: 6
#2Michael R. Folkert (UTSW: University of Texas Southwestern Medical Center)H-Index: 15
Last. Linda Farkas (UTSW: University of Texas Southwestern Medical Center)
view all 7 authors...
e16000Background: When, whether and in whom resection of the primary tumor for patients with metastatic colorectal cancer (CRC) is indicated remains incompletely elucidated, although a recent rando...
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#1Srinidhi Radhakrishnan (UTSW: University of Texas Southwestern Medical Center)
#2Suleyman Yasin Goksu (UTSW: University of Texas Southwestern Medical Center)
Last. Syed Mohammad Ali Kazmi (UTSW: University of Texas Southwestern Medical Center)
view all 9 authors...
4059Background: Anal squamous cell carcinoma (ASCC) is associated with significant symptom burden including pain, bleeding, and obstructive symptoms. However, the proportion of patients requiring p...
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#1Nicholas Levonyak (UTSW: University of Texas Southwestern Medical Center)
#2Mary P Hodges (Parkland Memorial Hospital)
Last. Syed Mohammad Ali Kazmi (UTSW: University of Texas Southwestern Medical Center)
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#1Davendra Sohal (UC: University of Cincinnati)H-Index: 21
#1Davendra Sohal (UC: University of Cincinnati)H-Index: 1
Last. Andrew M. Lowy (UCSD: University of California, San Diego)H-Index: 52
view all 12 authors...
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#1Mohsin Soleja (UTSW: University of Texas Southwestern Medical Center)
#2Suleyman Yasin Goksu (UTSW: University of Texas Southwestern Medical Center)
Last. David Hsieh (UTSW: University of Texas Southwestern Medical Center)H-Index: 3
view all 11 authors...
4103Background: Prior studies have observed under-utilization of adjuvant chemotherapy (ACT) in stage III colon cancer. Our aims were to observe the rate of utilization of ACT in very healthy or “i...
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