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Brendon J. Gurd
Queen's University
EndocrinologyPhysical therapyInterval trainingSkeletal muscleMedicine
116Publications
25H-index
1,617Citations
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Publications 120
Newest
#1Jacob T. Bonafiglia (Queen's University)H-Index: 6
#2Hashim Islam (Queen's University)H-Index: 3
Last. Christopher G. R. Perry (York University)H-Index: 11
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Abstract This study tested the hypotheses that 1) skeletal muscle biopsies performed with the Bergstrom needle evoke larger perceptions of pain and greater hemodynamic reactivity compared to biopsies performed with the microbiopsy needle, and 2) both needles yield samples with similar fibre type compositions when samples are collected at similar skeletal muscle depths. Fourteen healthy (age: 21.6 ± 3.2 years; VO2peak: 41.5 ± 5.8 mL/kg/min) males (n = 7) and females (n = 7) provided two resting s...
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#1Hashim Islam (Queen's University)H-Index: 3
#1Hashim IslamH-Index: 4
Last. Brendon J. GurdH-Index: 25
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Exercise-induced alterations in adipose tissue insulin and/or β-adrenergic signaling may contribute to increases in whole-body fat oxidation following acute exercise. Thus, we examined changes in insulin (Akt, AS160) and β-adrenergic (PKA) signaling proteins in subcutaneous adipose tissue and whole-body fat oxidation in overweight women following acute high-intensity interval exercise (HIIE). Overweight females completed two experimental sessions in a randomized order: 1) control (bed rest) and ...
#1Hashim Islam (Queen's University)H-Index: 3
#2Andrew Ma (UW: University of Waterloo)H-Index: 1
Last. Brendon J. Gurd (Queen's University)H-Index: 25
view all 8 authors...
Leucine-rich pentatricopeptide repeat motif-containing protein (LRP130) is implicated in the control of mitochondrial gene expression and oxidative phosphorylation in the liver, partly due to its interaction with peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α). To investigate LRP130’s role in healthy human skeletal muscle, we examined LRP130’s fiber-type distribution and subcellular localization (n = 6), as well as LRP130’s relationship with PGC-1α protein and citr...
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#1Travis J. Hrubeniuk (UNB: University of New Brunswick)H-Index: 2
#2Danielle R. Bouchard (UNB: University of New Brunswick)H-Index: 14
Last. Martin Sénéchal (UNB: University of New Brunswick)H-Index: 9
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BACKGROUND: Individuals with prediabetes are likely to progress to Type 2 diabetes. Although exercise training is an established method to improve glycemic control, the degree to which this translates into meaningful improvements, particularly in individuals with prediabetes, is unclear. The purpose of this meta-analysis was to investigate the ability of exercise training to improve 2-hour glucose tolerance beyond the smallest worthwhile difference in individuals with prediabetes. It was hypothe...
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#1Hashim Islam (UM: University of Michigan)H-Index: 1
#2David A. Hood (UM: University of Michigan)H-Index: 52
Last. Brendon J. Gurd (UM: University of Michigan)H-Index: 25
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Despite its widespread acceptance as the “master regulator” of mitochondrial biogenesis (i.e. the expansion of the mitochondrial reticulum), peroxisome proliferator-activated receptor (PPAR) gamma ...
4 CitationsSource
#1Jeremy J. Walsh (Children's Hospital of Eastern Ontario)H-Index: 6
#2Jacob T. Bonafiglia (UM: University of Michigan)H-Index: 6
Last. Brendon J. Gurd (UM: University of Michigan)H-Index: 25
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This study investigated the impact of exercise training on interindividual variability and response rates in body composition and cardiometabolic outcomes in adolescents with obesity. Postpubertal ...
1 CitationsSource
#1Michael Del Giudice (Queen's University)
#2Jacob T. Bonafiglia (Queen's University)H-Index: 6
Last. Brendon J. Gurd (Queen's University)H-Index: 25
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Abstract Objectives To test the hypothesis that observed maximal oxygen uptake (VO2max) and time to fatigue (TTF) responses to two identical periods of standardized high-intensity interval training are reproducible. Design Fourteen recreationally active and healthy young males completed two identical four-week periods of high-intensity interval training (4 × 4-minute intervals at 90-95% maximum heart rate [HRmax] separated by 3-minute periods of active recovery at 70-75% HRmax). Training periods...
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#1Hashim Islam (Queen's University)H-Index: 3
#2Jacob T. Bonafiglia (Queen's University)H-Index: 6
Last. Brendon J. Gurd (Queen's University)H-Index: 25
view all 6 authors...
Purpose To examine the relationship between changes in nuclear factor erythroid 2-related factor 2 (Nrf2) expression and markers of mitochondrial biogenesis in acutely and chronically exercised human skeletal muscle.
1 CitationsSource
#1Hashim Islam (UM: University of Michigan)H-Index: 3
#2Miss Tina L. Siemens (UM: University of Michigan)
Last. Brendon J. Gurd (UM: University of Michigan)H-Index: 25
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Young adults (n=68 [52 F]; age=21±3 y; VO2peak: 41±6 mL/kg/min) were randomized into a no-exercise control (CTL: n=15), Tabata (n=26), or vigorous-intensity continuous training (VICT; n=27) group f...
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#1Nicholas Preobrazenski (UM: University of Michigan)H-Index: 2
#2Hashim Islam (UM: University of Michigan)H-Index: 3
Last. Brendon J. Gurd (UM: University of Michigan)H-Index: 25
view all 6 authors...
This study tested the hypothesis that a novel, gravity-induced BFR aerobic exercise (AE) model will result in greater activation of the AMPK-PGC-1α pathway compared to work rate-matched non-BFR. Th...
1 CitationsSource
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