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Mark W. Jackwood
University of Georgia
SerotypeVirologyImmunologyVirusBiology
114Publications
33H-index
3,212Citations
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Publications 109
Newest
#1Jongseo Mo (UGA: University of Georgia)
#2Michael John Angelichio (Idexx Laboratories)
Last. Mark W. Jackwood (UGA: University of Georgia)H-Index: 33
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Abstract Infectious bronchitis (IB) is a highly contagious upper respiratory tract disease of chickens caused by infectious bronchitis virus (IBV), which has various serotypes that do not cross-protect. Vaccine control strategies for this virus are only effective when designed around the currently circulating serotypes. It is essential to not only rapidly detect IBV but also to identify the type of virus causing disease. Six TaqMan™-based quantitative real-time RT-PCR assays (Universal, Ark, Mas...
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#1Emily J. Aston (UGA: University of Georgia)H-Index: 1
#2Mark W. Jackwood (UGA: University of Georgia)H-Index: 33
Last. Brian J. Jordan (UGA: University of Georgia)H-Index: 8
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Abstract Commercial broilers are commonly exposed to gaseous ammonia (NH3) originating from degradation of nitrogen-containing excreta in the litter during the grow-out period. Ammonia concentrations in the air are higher in poorly ventilated houses and appear to coincide with the elevated incidence of respiratory disease occurring during the winter months. This study examined the effect of NH3 on the immune response to infectious bronchitis virus (IBV) vaccination and protection against homolog...
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#1Jo Anne Crum (UGA: University of Georgia)H-Index: 1
#2Daniel G. Mead (UGA: University of Georgia)H-Index: 18
Last. David E. Stallknecht (UGA: University of Georgia)H-Index: 49
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ABSTRACT During summer and early fall of 2012, the US experienced the largest outbreak of hemorrhagic disease (HD) on record; deer (both Odocoileus virginianus and Odocoileus hemionus) in 35 states...
2 CitationsSource
#1Emily J. AstonH-Index: 1
#2Brian J. JordanH-Index: 8
Last. Mark W. JackwoodH-Index: 33
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Avian respiratory disease causes significant economic losses in commercial poultry. Because of the need to protect long-lived poultry against respiratory tract pathogens from an early age, vaccination programs for pullets typically involve serial administration of a variety of vaccines, including infectious bronchitis virus (IBV), Newcastle disease virus (NDV), and infectious laryngotracheitis virus (ILTV). Often the interval between vaccinations is only a matter of weeks, yet it is unknown whet...
1 CitationsSource
#1Grace A. Albanese (UGA: University of Georgia)H-Index: 1
#2Dong-Hun Lee (USDA: United States Department of Agriculture)H-Index: 23
Last. Brian J. Jordan (UGA: University of Georgia)H-Index: 8
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Abstract Almost all commercial poultry are vaccinated against avian coronavirus infectious bronchitis virus (IBV) using live attenuated vaccines mass administered by spray at day of hatch. Although many different types of IBV vaccines are used successfully, the ArkDPI serotype vaccine, when applied by spray, does not infect and replicate sufficiently to provide protection against homologous challenge. In this study, we examined a different Ark vaccine strain (Ark99), which is no longer used comm...
1 CitationsSource
7 CitationsSource
#1Christina M. Leyson (UGA: University of Georgia)H-Index: 4
#2Deborah A. Hilt (UGA: University of Georgia)H-Index: 23
Last. Mark W. Jackwood (UGA: University of Georgia)H-Index: 33
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SUMMARY The Arkansas Delmarva Poultry Industry (ArkDPI) infectious bronchitis virus (IBV) vaccine is effective when administered by eye drop, where the vaccine virus is able to infect and replicate well in birds and is able to induce protection against homologous challenge. However, accumulating evidence indicates that the ArkDPI vaccine is ineffective when applied by hatchery spray cabinet using the same manufacturer-recommended dose per bird. For this study, we aimed to determine the minimum i...
2 CitationsSource
#1Christina M. Leyson (UGA: University of Georgia)H-Index: 4
#2Brian J. Jordan (UGA: University of Georgia)H-Index: 8
Last. Mark W. Jackwood (UGA: University of Georgia)H-Index: 33
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Abstract Infectious bronchitis virus is an important respiratory pathogen in chickens. The IBV S1 spike is a viral structural protein that is responsible for attachment to host receptors and is a major target for neutralizing antibodies. To date, there is no experimentally determined structure for the IBV S1 spike. In this study, we sought to find a predicted tertiary structure for IBV S1 using I-TASSER, which is an automated homology modeling platform. We found that the predicted structures obt...
2 CitationsSource
#1Muhammad Rizwan (Georgia Institute of Technology)H-Index: 2
#2Brandon T. Carroll (Georgia Institute of Technology)H-Index: 2
Last. Mark W. Jackwood (UGA: University of Georgia)H-Index: 33
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Extreme learning machine (ELM) and support vector machine (SVM) classifiers are developed to detect rales (a gurgling sound that is a symptom of respiratory diseases in poultry). These classifiers operate on Mel-scaled spectral features calculated from recordings of healthy and sick chickens during a vaccine trial. Twenty minutes of labeled data were used to train and test the classifiers, then they were run on the full 25 days of continuous recordings from the healthy and sick chickens. The res...
2 CitationsSource
#2Deborah A. HiltH-Index: 23
Last. Mark W. JackwoodH-Index: 33
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Abstract SUMMARY. The Arkansas-Delmarva poultry industry (ArkDPI) infectious bronchitis virus (IBV) vaccine is effective when administered by eye drop, where the vaccine virus is able to infect and replicate well in birds and is able to induce protection against homologous challenge. However, accumulating evidence indicates that ArkDPI vaccine is ineffective when applied by hatchery spray cabinet using the same manufacturers' recommended dose per bird. For this study, we aimed to determine the m...
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