Surya P. Bhatt
University of Alabama at Birmingham
Physical therapyCOPDDiseaseDiabetes mellitusMedicine
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Publications 246
#1Surya P. Bhatt (UAB: University of Alabama at Birmingham)H-Index: 24
#1Surya P. BhattH-Index: 24
#2Anoop MisraH-Index: 47
Last. Ravindra Mohan Pandey (AIIMS: All India Institute of Medical Sciences)H-Index: 49
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Abstract Background and Aims Transcription factor 7 like 2 (TCF7L-2) polymorphism has been associated with adipocyte metabolism and insulin resistance. Genetic investigations of non-alcoholic fatty liver disease (NAFLD) with obesity, type 2 diabetes mellitus (T2DM) and atherosclerosis are unknown. This study was designed to investigate the association of rs7903146 (C/T) polymorphism of TCF7L-2 gene with non-alcoholic fatty liver disease (NAFLD) in Asian Indians. Methods In this case-control stud...
#1George R. Washko (Brigham and Women's Hospital)H-Index: 51
#2Laura A. Colangelo (NU: Northwestern University)H-Index: 43
Last. Ravi Kalhan (NU: Northwestern University)H-Index: 23
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Abstract Background Peak lung function and rate of decline predict future airflow obstruction and non-respiratory comorbid conditions. Associations between lung function trajectories and emphysema have not been explored. Methods Using data from the population-based CARDIA Study, we sought to describe the prevalence of visually ascertained emphysema at multiple time points and contextualize its development based upon participant's adult life course measures of lung function. 3171 men and women we...
#1David C. LaFon (UAB: University of Alabama at Birmingham)H-Index: 3
#2Surya P. Bhatt (UAB: University of Alabama at Birmingham)H-Index: 24
Last. J. Michael WellsH-Index: 17
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Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality worldwide [1]. Pulmonary hypertension (PH) has been associated with reduced survival among individuals with COPD [2] and is an independent risk factor for mortality following acute exacerbations of COPD (AECOPD) [3]. Measurement of the pulmonary artery to aorta (PA:A) ratio by computed tomography (CT) and assessment of PA enlargement (PA:A>1) outperforms echocardiography in identifying PH in severe COPD [4], a...
#1Surya P. BhattH-Index: 24
#2Anoop MisraH-Index: 47
Last. Namrata SinghH-Index: 12
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Vitamin D deficiency may contribute to etiology of type 2 diabetes in Asian Indians. The objectives of this study was to evaluate effect of vitamin D supplementation on glycemic profile and body composition in prediabetic and vitamin D deficient overweight/obese Asian Indian women. In this open-label randomized placebo-controlled trial (78 weeks duration), 121 females (aged 20–60 years) with prediabetes and vitamin D deficiency were randomly allocated in intervention (n, 61) and placebo (n, 60) ...
2 CitationsSource
#1Tracy Hwangpo (UAB: University of Alabama at Birmingham)H-Index: 2
#2Zhixin Wang (UAB: University of Alabama at Birmingham)
Last. Harry W. Schroeder (UAB: University of Alabama at Birmingham)H-Index: 43
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Immunoglobulin replacement therapy (IGRT) can protect against lung function decline in CVID. We tested whether increasing IgG dosage was beneficial in patients who exhibited a decline in forced expiratory flow at 25–75% (FEF25–75%) even though they were receiving IgG doses within the therapeutic range. Of 189 CVID patients seen over 12 years, 38 patients met inclusion criteria, were seen on ≥ 3 visits, and demonstrated a ≥ 10% decrease in FEF25–75% from visits 1 to 2. FEF25–75%, forced expirator...
#1Elizabeth C. Oelsner (Columbia University)H-Index: 11
#2Pallavi Balte (Columbia University)H-Index: 5
Last. Sachin Yende (University of Pittsburgh)H-Index: 27
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Summary Background Former smokers now outnumber current smokers in many developed countries, and current smokers are smoking fewer cigarettes per day. Some data suggest that lung function decline normalises with smoking cessation; however, mechanistic studies suggest that lung function decline could continue. We hypothesised that former smokers and low-intensity current smokers have accelerated lung function decline compared with never-smokers, including among those without prevalent lung diseas...
2 CitationsSource
#1Surya P. Bhatt (UAB: University of Alabama at Birmingham)H-Index: 24
#2Mark T. Dransfield (UAB: University of Alabama at Birmingham)H-Index: 41
#1Peter J. Castaldi (Brigham and Women's Hospital)H-Index: 25
#2Adel Boueiz (Brigham and Women's Hospital)
Last. John E. Hokanson (University of Colorado Denver)H-Index: 58
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Abstract COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there is not yet consensus on how many COPD subtypes there are and how they should be defined. The COPDGene study, which has generated ten-year longitudinal chest imaging, spirometry, and molecular data, is a rich resource for relating COPD phenotypes to underlying genetic and molecular mechanisms. In this article, we place COPDGene clustering studies in context with other highly cited COPD clustering studies, ...
Objective Bronchodilator responsiveness (BDR) is prevalent in COPD, but its clinical implications remain unclear. We explored the significance of BDR, defined by post-bronchodilator change in FEV1 (BDRFEV1) as a measure reflecting the change in flow and in FVC (BDRFVC) reflecting the change in volume.