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Shin-ichiro Ueda
Kurume University
12Publications
7H-index
214Citations
Publications 12
Newest
#1Kenichiro Yaita (Kurume University)H-Index: 4
#2Hideki Ohshima (Kurume University)H-Index: 4
Last.Hiroshi Watanabe (Kurume University)H-Index: 24
view all 9 authors...
Source
#1Hiroshi Koiwaya (Kurume University)H-Index: 7
#2Hisashi Kai (Kurume University)H-Index: 31
Last.Tsutomu Imaizumi (Kurume University)H-Index: 16
view all 19 authors...
macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 2001;7:161–71. [16] Kim JY, van de Wall E, Laplante M, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest 2007;117:2621–37. [17] Liu Y, Zhang Y, Schmelzer K, et al. The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proc Natl Acad Sci U S A 2005;102:16747–52. [18] Pang W, Li N, Ai D, Niu XL...
Source
#1Daisuke Fukui (Kurume University)H-Index: 5
#2Hisashi Kai (Kurume University)H-Index: 31
Last.Tsutomu Imaizumi (Kurume University)H-Index: 16
view all 12 authors...
A 59-year-old woman was admitted because of cyanosis and dyspnea on exertion and at rest. In her childhood, she was suspected of having ventricular septal defect (VSD), but she refused to undergo cardiac catheterization and operation. Dyspnea on exertion gradually developed after adolescence. On admission, chest roentgenography demonstrated enlarged cardiac silhouette with elevated cardiac apex, a right aortic arch, and enlargement of the main pulmonary arteries and their major branches with inc...
12 CitationsSource
#1Shin-ichiro Ueda (Kurume University)H-Index: 7
#2Sho-ichi Yamagishi (Kurume University)H-Index: 68
Last.Tsutomu Imaizumi (Kurume University)H-Index: 16
view all 5 authors...
Oxidative stress and inflammation are involved in cardiac remodeling after acute myocardial infarction (AMI). We have found that pigment epithelium-derived factor (PEDF) inhibits vascular inflammation through its anti-oxidative properties. However, effects of PEDF on cardiac remodeling after AMI remain unknown. We investigated whether PEDF could inhibit left ventricular remodeling and improve cardiac function in rats with AMI. AMI was induced in 8-week-old Sprague-Dawley rats by ligation of the ...
29 CitationsSource
#1Shin-ichiro Ueda (Kurume University)H-Index: 7
#2Ikuyo MiyakeH-Index: 13
Last.Sho-ichi Yamagishi (Kurume University)H-Index: 68
view all 11 authors...
6 CitationsSource
#1Daisuke FukuiH-Index: 5
#2Hisashi KaiH-Index: 11
Last.Tsutomu ImaizumiH-Index: 1
view all 12 authors...
#1Miwako TsunosueH-Index: 1
#2Naomi MashikoH-Index: 1
Last.Sho-ichi Yamagishi (Kurume University)H-Index: 68
view all 12 authors...
Diabetes is a major risk factor for cardiovascular disease (CVD) morbidity and mortality, and the incidence of CVD is 2–4 times greater in diabetic patients than in a general population [1]. There is a growing body of evidence that postprandial hyperglycemia plays an important role in the development and progression of CVD [2, 3]. Indeed, the DECODE study revealed that 2-h postload hyperglycemia was associated with an increased risk of mortality from CVD, independent of fasting plasma glucose [2...
18 CitationsSource
#1Ako Fukami (Kurume University)H-Index: 12
#2Hisashi Adachi (Kurume University)H-Index: 32
Last.Tsutomu Imaizumi (Kurume University)H-Index: 73
view all 15 authors...
High mobility group box 1 (HMGB1), a nonhistone chromatin-associated protein, is implicated as a mediator of both infectious and non-infectious inflammatory conditions. Clinical research on this protein in humans just has begun; serum HMGB1 was reported to be elevated in a small number of critically ill patients suffering from sepsis. However, the kinetics, distribution and factors associated with circulating HMGB1 are unknown in a general population. In this study, we examined these issues in a...
30 CitationsSource
#1Sho-ichi Yamagishi (Kurume University)H-Index: 68
#2Hisashi Adachi (Kurume University)H-Index: 32
Last.Tsutomu Imaizumi (Kurume University)H-Index: 73
view all 12 authors...
Background Nonenzymatic modification of proteins by reducing sugars leads to the formation of advanced glycation end products (AGEs), whose process has been reported to progress under diabetes. Recently, diet has been found to be a major environmental source of proinflammatory AGEs in humans. Further, fats or meat-derived products processed by high heat such as broiling have been shown to contain more AGEs than carbohydrates boiled for longer periods. Since circulating levels of low-density lipo...
5 CitationsSource
#1Katsuhiko Takenaka (Kurume University)H-Index: 14
#2Sho-ichi Yamagishi (Kurume University)H-Index: 68
Last.Tsutomu Imaizumi (Kurume University)H-Index: 73
view all 10 authors...
Abstract Objectives Although remarkable therapeutic advances in the treatment of acute coronary syndromes (ACS) have been made with anti-platelet therapy, the therapeutic options may be limited by considerable side effects. Pigment epithelium-derived factor (PEDF) has anti-oxidative properties and may play a protective role against atherosclerosis. In this study, we investigated whether PEDF prevented occlusive thrombus formation in rats. Methods and results Occlusive thrombus formation was indu...
40 CitationsSource
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