Jerry Zhou
University of Sydney
AntigenAntibodyAntibody microarrayColorectal cancerMedicine
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Publications 21
#1Jerry ZhouH-Index: 5
Last. John D. BrannanH-Index: 4
view all 4 authors...
Variability during spirometry can persist despite control of technical and personal factors. We postulate spirometry induces gastro-oesophageal reflux (GOR), which may cause variability and affect results of spirometry. Fifty-eight (58) subjects undergoing GOR investigation with oesophageal manometry and 24hr pH monitoring were recruited. Oesophageal dysmotility and GOR were assessed as part of clinical care. Subjects performed 2 sets of spirometry separated by a 10-minute rest period. The asses...
#1Jerry Zhou (USYD: University of Sydney)H-Index: 5
Last. Vincent T. Ho (USYD: University of Sydney)H-Index: 71
view all 3 authors...
A proportion of laparoscopic sleeve gastrectomy patients experience symptoms of regurgitation and epigastric pain postoperation. The appearance of gastric sleeve contractions has been documented but its implications have not been adequately investigated. This case describes a 61-year-old female following laparoscopic sleeve gastrectomy. The patient underwent high-resolution impedance esophageal manometry that identified compartmentalized pressurization leading to propagating contractions through...
The low socioeconomic region of Greater Western Sydney (GWS) has higher than average rates of gastrointestinal symptoms. The relationship between prescription drug usage and constipation has not been explored. The aim of this study was to investigate the impact of drug use on constipation in the elderly population of GWS (NSW, Australia). A random selection of elderly residents completed a postal questionnaire for constipation and drug use (response 30.7%). Bivariate associations between constip...
2 CitationsSource
Background/Aims: High-resolution oesophageal manometry utilises water swallows to evaluate oesophageal function. However, small volumes of water are not representative of normal eating and as a result often produce normal manometry studies in patients with dysphagia. This study sets out to establish optimal diagnostic thresholds for semi-solid solid swallows and evaluate their ability to uncover motility abnormalities in patients with motility disorders. Method: Manometry was performed using ten...
Effective digestion requires propagation of food along the entire length of the gastrointestinal tract. This process involves coordinated waves of peristalsis produced by enteric neural cell types, including different categories of interstitial cells of Cajal (ICC). Impaired food transport along the gastrointestinal tract, either too fast or too slow, causes a range of gut motility disorders that affect millions of people worldwide. Notably, loss of ICC has been shown to affect gut motility. Pat...
4 CitationsSource
#1Ming Yan TeoH-Index: 1
#2Jerry Zhou (USYD: University of Sydney)H-Index: 5
Last. John D. Brannan ('JHCH': John Hunter Hospital)H-Index: 4
view all 4 authors...
Background: Variability during spirometry can persist despite control of technical and personal factors. We postulate spirometry induces GOR, which may cause variability of spirometry. Aims and Objectives: Pilot study assessing prevalence of GOR during spirometry and its effects on spirometry variability in subjects having outpatient GOR assessment. Methods: At the end of oesophageal manometry and 24hr pH monitoring, 56 subjects performed 2 sets of spirometry separated by a 10-minute break. We q...
1 CitationsSource
#1Kelvin K. L. Wong (USYD: University of Sydney)H-Index: 22
#2Lauren C. Y. Tang (USYD: University of Sydney)
Last. Vincent T. Ho (USYD: University of Sydney)H-Index: 71
view all 4 authors...
ABSTRACTAnticholinergic drugs are well-known to cause adverse effects, such as constipation, but their effects on baseline contractile activity in the gut driven by slow waves is not well established. In a video-based gastrointestinal motility monitoring (GIMM) system, a mouse's small intestine was placed in Krebs solution and recorded using a high definition camera. Untreated controls were recorded for each specimen, then treated with a therapeutic concentration of the drug, and finally, treate...
#1Larissa Belov (USYD: University of Sydney)H-Index: 16
#2Susannah Hallal (USYD: University of Sydney)H-Index: 4
Last. Richard I. Christopherson (USYD: University of Sydney)H-Index: 28
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DotScan antibody microarrays were initially developed for the extensive surface profiling of live leukemia and lymphoma cells. DotScan's diagnostic capability was validated with an extensive clinical trial using mononuclear cells from the blood or bone marrow of leukemia or lymphoma patients. DotScan has also been used for the profiling of surface proteins on peripheral blood mononuclear cells (PBMC) from patients with HIV, liver disease, and stable and progressive B-cell chronic lymphocytic leu...
1 CitationsSource
#2Kelvin K. L. WongH-Index: 22
Last. Vincent T. HoH-Index: 71
view all 8 authors...