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Lingzhong Fan
Chinese Academy of Sciences
Diffusion MRIPsychologyNeuroscienceHuman brainBrain mapping
68Publications
20H-index
1,498Citations
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Publications 72
Newest
#1Bin He (CAS: Chinese Academy of Sciences)
#2Zhengyi Yang (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Tianzi JiangH-Index: 67
view all 8 authors...
Non-human primate models are widely used in studying the brain mechanism underlying brain development, cognitive functions and psychiatric disorders. Neuorimaging techniques, such as magnetic resonance imaging, play an important role in the examinations of brain structure and functions. As an indispensable tool for brain imaging data analysis, brain atlases have been extensively investigated and a variety of versions constructed. These atlases diverge in the criteria based on which they are plot...
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#2Yongfeng YangH-Index: 10
Last. Xueqin SongH-Index: 12
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Objectives: Abnormal activity of the subgenual anterior cingulate cortex (sACC) is implicated in depression, suggesting the sACC as a potentially effective target for therapeutic modulation in cases resistant to conventional treatments (treatment-resistant depression, TRD). We hypothesized that areas in the prefrontal cortex (PFC) with direct fiber connections to the sACC may be particularly effective sites for treatment using transcranial magnetic stimulation (TMS). The aim of this study was to...
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#1Ang Li (CAS: Chinese Academy of Sciences)H-Index: 2
#2Andrew Zalesky (University of Melbourne)H-Index: 42
Last. Guangxiang Rao (CAS: Chinese Academy of Sciences)
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Mounting evidence suggests that function and connectivity of the striatum is disrupted in schizophrenia1–5. We have developed a new hypothesis-driven neuroimaging biomarker for schizophrenia identification, prognosis and subtyping based on functional striatal abnormalities (FSA). FSA scores provide a personalized index of striatal dysfunction, ranging from normal to highly pathological. Using inter-site cross-validation on functional magnetic resonance images acquired from seven independent scan...
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#1Na Luo (CAS: Chinese Academy of Sciences)H-Index: 2
#2Jing Sui (CAS: Chinese Academy of Sciences)H-Index: 31
Last. Vince D. Calhoun (Georgia Institute of Technology)H-Index: 2
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Brain structural networks have been shown to consistently organize in functionally meaningful architectures covering the entire brain. However, to what extent brain structural architectures match the intrinsic functional networks in different functional domains remains under explored. In this study, based on independent component analysis, we revealed 45 pairs of structural-functional (S-F) component maps, distributing across 9 functional domains, in both a discovery cohort (n=6005) and a replic...
1 CitationsSource
#1Weizheng Yan (CAS: Chinese Academy of Sciences)H-Index: 2
#2Vince D. CalhounH-Index: 93
Last. Jing Sui (CAS: Chinese Academy of Sciences)H-Index: 31
view all 25 authors...
Abstract Background Current fMRI-based classification approaches mostly use functional connectivity or spatial maps as input, instead of exploring the dynamic time courses directly, which does not leverage the full temporal information. Methods Motivated by the ability of recurrent neural networks (RNN) in capturing dynamic information of time sequences, we propose a multi-scale RNN model, which enables classification between 558 schizophrenia and 542 healthy controls by using time courses of fM...
1 CitationsSource
#1Rongtao Jiang (CAS: Chinese Academy of Sciences)H-Index: 6
#2Vince D. Calhoun (Georgia Institute of Technology)H-Index: 93
Last. Jing SuiH-Index: 31
view all 13 authors...
4 CitationsSource
#1Xiaoluan Xia (TUT: Taiyuan University of Technology)H-Index: 1
#2Lingzhong Fan (CAS: Chinese Academy of Sciences)H-Index: 20
Last. Tianzi JiangH-Index: 67
view all 11 authors...
Limited in part by the spatial resolution of typical in vivo magnetic resonance imaging (MRI) data, recent neuroimaging studies have only identified a connectivity-based shell-core-like partitioning of the nucleus accumbens (Acb) in humans. This has hindered the process of making a more refined description of the Acb using non-invasive neuroimaging technologies and approaches. In this study, high-resolution ex vivo macaque brain diffusion MRI data were acquired to investigate the tractography-ba...
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#1Xiaoluan Xia (TUT: Taiyuan University of Technology)H-Index: 1
#2Lingzhong Fan (CAS: Chinese Academy of Sciences)H-Index: 20
Last. Tianzi JiangH-Index: 67
view all 8 authors...
Although the evolutionarily conserved functions of the ventral striatal components have been used as a priori knowledge for further studies, whether these functions are conserved between species remains unclear. In particular, whether macroscopic connectivity supports this given the disproportionate volumetric differences between species in the brain regions that project to the ventral striatum, including the prefrontal and limbic areas, has not been established. The evolutionarily conserved fun...
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#1Dongya Wu (CAS: Chinese Academy of Sciences)H-Index: 1
#2Lingzhong Fan (CAS: Chinese Academy of Sciences)H-Index: 20
Last. Tianzi JiangH-Index: 67
view all 7 authors...
Many studies showed that anatomical connectivity supports both anatomical and functional hierarchies that span across the primary and association cortices in the cerebral cortex. However, it remains unclear whether a hierarchy of connectivity-function relationship (CFR) exists across the human cortex as well as how to characterize the hierarchy of this CFR if it exists. We first addressed whether anatomical connectivity could be used to predict functional activations across different functional ...
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#1Shengfeng LiuH-Index: 4
#2Haiying Wang (Harbin University of Science and Technology)H-Index: 1
Last. Jing SuiH-Index: 31
view all 32 authors...
Multimodal fusion has been regarded as a promising tool to discover covarying patterns of multiple imaging types impaired in brain diseases, such as schizophrenia (SZ). In this article, we aim to investigate the covarying abnormalities underlying SZ in a large Chinese Han population (307 SZs, 298 healthy controls [HCs]). Four types of magnetic resonance imaging (MRI) features, including regional homogeneity (ReHo) from resting-state functional MRI, gray matter volume (GM) from structural MRI, fr...
5 CitationsSource
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