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Carole C. Perry
Nottingham Trent University
271Publications
44H-index
8,634Citations
Publications 271
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#1Victor Volkov (NTU: Nottingham Trent University)H-Index: 8
#2Riccardo Chelli (UniFI: University of Florence)H-Index: 23
Last.C.C. Perry (NTU: Nottingham Trent University)
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Abstract In this study, we explore the molecular mechanisms of the stability of indigo chromophores and pigments. Assisted with density functional theory, we compare visible, infrared and Raman spectral properties of model molecules, chromophores and pigments derived from living organisms. Using indigo carmine as a representative model system, we characterize the structure and dynamics of the chromophore in the first electronic excited state using femtosecond visible pump-infrared probe spectros...
#1Myles J. Terrey (NTU: Nottingham Trent University)
#2Ashley Holmes (NTU: Nottingham Trent University)
Last.Warren B. Cross (NTU: Nottingham Trent University)H-Index: 9
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There is high demand for new methods to modify peptides, for application in drug discovery and biomedicine. A C–H functionalization protocol for the olefination of tryptophan residues in peptides is described. The modification is successful for Trp residues at any position in the peptide, has broad scope in the styrene coupling partner, and offers opportunities for conjugating peptides with other biomolecules. For peptides containing both Trp and Phe, directing group manipulation enables full co...
#1Graham J. HickmanH-Index: 3
#2David J. BeltonH-Index: 14
Last.Carole C. PerryH-Index: 44
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There is an increasing demand for environmentally sustainable sourcing of ingredients for the food, pharmaceutical and supplements industries. In the case of calcium carbonate (E170) as by-products from the egg and shellfish processing industries these have the potential to be sustainably sourced. In addition to their green credentials, biogenic carbonates have intrinsic benefits in terms of their chemical composition, such as a low heavy metal burden. However, their biogenic origin can potentia...
#1Victor VolkovH-Index: 8
#2Graham J. HickmanH-Index: 3
Last.Carole C. PerryH-Index: 44
view all 4 authors...
Equisetum species are primitive vascular plants that benefit from the biogenesis of silica bio-organic inclusions in their tissues and participate in the annual biosilica turnover in local eco-systems. As means of Equisetum reproduction and propagation, spores are expected to reflect the evolutionary adaptation of the plants to the climatic conditions at different times of the year. Combining methods of Raman and scanning electron microscopy and assisted with density functional theory, we conduc...
#1David J. Belton (NTU: Nottingham Trent University)H-Index: 14
#2Graham J. Hickman (NTU: Nottingham Trent University)H-Index: 3
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
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ABSTRACTCalcium carbonate (E170) is a common food and pharmaceutical additive/ingredient. In addition to a source of calcium, the carbonate has uses including as a colour, acidity regulator and bulking agent. Globally, a range of regulatory agencies and pharmacopoeia control the analyses and specification of additives in food, supplements, pharmaceutical substances and excipients. Accordingly, a range of specifications and analyses exist for calcium carbonate depending on the application and mar...
#1Myles J. Terrey (NTU: Nottingham Trent University)
#2Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
Last.Warren B. Cross (NTU: Nottingham Trent University)H-Index: 9
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New methods for peptide modification are in high demand in drug discovery, chemical biology, and materials chemistry; methods that modify natural peptides are particularly attractive. A Pd-catalyzed, C–H functionalization protocol for the olefination of phenylalanine residues in peptides is reported, which is compatible with common amino acid protecting groups, and the scope of the styrene reaction partner is broad. Bidentate coordination of the peptide to the catalyst appears crucial for the su...
#1Daniel Oliver (NTU: Nottingham Trent University)H-Index: 1
#2Monika Michaelis (NTU: Nottingham Trent University)H-Index: 2
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
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Polypeptide based biosilica composites show promise as next generation multi-functional nano-platforms for diagnostics and bio-catalytic applications. Following the identification of a strong silica binder (LDHSLHS) by phage display, we conduct structural analysis of the polypeptide at the interface with amorphous silica nanoparticles in an aqueous environment. Our approach relies on modelling infrared and Raman spectral responses using predictions of molecular dynamics simulations and quantum s...
#1Patrick R. Huddleston (NTU: Nottingham Trent University)H-Index: 6
#2Victor Volkov (NTU: Nottingham Trent University)H-Index: 8
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
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Diversity of photo-switching structural elements open up new opportunities in the engineering of light driven reshaping of matter, in catalysis on-click including photodynamic cancer therapy, in light sensitive transport control and in data storage. Assisted with quantum calculations we explore the photo-physical properties of novel 3,3-azothiophene molecular systems, the synthesis of which we reported recently. In the considered azothiophenes, upon exposure to radiation at 365 nm and at 530 nm...
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