Match!
David J. Keene
University of Oxford
33Publications
7H-index
152Citations
Publications 33
Newest
#1David J. Keene (University of Oxford)H-Index: 7
#2Hessam Soutakbar (University of Oxford)H-Index: 1
Last.Andrew Carr (University of Oxford)H-Index: 92
view all 11 authors...
ABSTRACT Objectives The Getting it Right: Addressing Shoulder Pain (GRASP) trial is a large-scale, multicentre, 2 × 2 factorial randomised controlled trial investigating clinical and cost-effectiveness of a progressive exercise programme versus best-practice advice, with or without corticosteroid injection, for treating people with rotator cuff disorders. Here we describe the development, implementation and details of the physiotherapy-led interventions. Methods Medical Research Council guidance...
#1David J. Keene (University of Oxford)H-Index: 7
#2Joseph Alsousou (University of Oxford)H-Index: 8
Last.K. Willett (University of Oxford)H-Index: 15
view all 9 authors...
Aim Slow recovery and disability after Achilles tendon rupture are major challenges. Platelet Rich Plasma (PRP) is an autologous supraphysiological concentration of platelets from whole blood that has demonstrated positive cellular and physiological effects on healing in the laboratory and is widely used in musculoskeletal treatments. However, evidence from adequately powered, robust clinical trials is lacking. We aimed to determine the clinical efficacy of PRP for treatment of acute Achilles te...
#1David J. Keene (University of Oxford)H-Index: 7
#2Joseph Alsousou (University of Liverpool)H-Index: 8
Last.Michael Maia Schlüssel (University of Oxford)H-Index: 13
view all 12 authors...
Introduction Platelet Rich Plasma (PRP), an autologous supraphysiological concentration of platelets from whole blood, has demonstrated positive cellular and physiological effects on healing in the laboratory. However, evidence from robust clinical trials is lacking. We aimed to determine the clinical efficacy of PRP for treating acute Achilles tendon rupture. Materials and methods 230 adults starting non-surgical management within 12 days of rupture were randomised to PRP injection or dry needl...
#1Michael Maia Schlüssel (University of Oxford)H-Index: 13
#2David J. Keene (John Radcliffe Hospital)H-Index: 7
Last.Susan Dutton (University of Oxford)H-Index: 23
view all 7 authors...
Background There has been a recent steep growth in platelet-rich plasma (PRP) use for musculoskeletal conditions, but findings from high quality clinical trial data are lacking in the literature. Here, we describe the statistical analysis plan (SAP) for the Platelet-rich plasma in Achilles Tendon Healing 2 (PATH-2) trial.
#1Michael Maia Schlüssel (University of Oxford)H-Index: 13
#2David J. Keene (University of Oxford)H-Index: 7
Last.Jacqueline M. Thompson (University of Oxford)H-Index: 3
view all 12 authors...
OBJECTIVES: To develop and externally validate a prognostic model for poor recovery after ankle sprain. SETTING AND PARTICIPANTS: Model development used secondary data analysis of 584 participants from a UK multicentre randomised clinical trial. External validation used data from 682 participants recruited in 10 UK emergency departments for a prospective observational cohort. OUTCOME AND ANALYSIS: Poor recovery was defined as presence of pain, functional difficulty or lack of confidence in the a...
#1David J. Keene (University of Oxford)H-Index: 7
#2Michael Maia Schlüssel (University of Oxford)H-Index: 13
Last.Philip Hormbrey (University of Oxford)
view all 15 authors...
BACKGROUND: Ankle sprains are very common injuries. Although recovery can occur within weeks, around one-third of patients have longer-term problems. OBJECTIVES: To develop and externally validate a prognostic model for identifying people at increased risk of poor outcome after an acute ankle sprain. DESIGN: Development of a prognostic model in a clinical trial cohort data set and external validation in a prospective cohort study. SETTING: Emergency departments (EDs) in the UK. PARTICIPANTS: Adu...
#1Miguel FernandezH-Index: 8
#2Laura Arnel (John Radcliffe Hospital)
Last.Tim Chesser (North Bristol NHS Trust)H-Index: 7
view all 14 authors...
Objective To determine research priorities in fragility fractures of the lower limb and pelvis which represent the shared priorities of patients, their friends and families, carers and healthcare professionals. Design/setting A national (UK) research priority setting partnership. Participants Patients over 60 years of age who have experienced a fragility fracture of the lower limb or pelvis; carers involved in their care (both in and out of hospital); family and friends of patients; healthcare p...
1234