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Sonia S. Kupfer
University of Chicago
CancerColorectal cancerDiabetes mellitusGeneral surgeryMedicine
130Publications
20H-index
1,396Citations
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Publications 137
Newest
#1Brandie Heald (Cleveland Clinic)H-Index: 16
#2Heather Hampel (OSU: Ohio State University)H-Index: 50
Last. Y. Nancy You (University of Texas MD Anderson Cancer Center)H-Index: 24
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Multigene panel tests for hereditary cancer syndromes are increasingly utilized in the care of colorectal cancer (CRC) and polyposis patients. However, widespread availability of panels raises a number of questions including which patients should undergo testing, which genes should be included on panels, and the settings in which panels should be ordered and interpreted. To address this knowledge gap, key questions regarding the major issues encountered in clinical evaluation of hereditary CRC a...
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#1Jessica Stoll (U of C: University of Chicago)H-Index: 3
#2E RosenthalH-Index: 6
Last. Sonia S. Kupfer (U of C: University of Chicago)H-Index: 20
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PURPOSEPrior estimates of breast cancer risk in women with Lynch syndrome (LS) range from population risk to 18-fold increased risk with reported differences by gene. Here, breast cancer rates were...
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#1Charles Muller (U of C: University of Chicago)H-Index: 2
#2Matthew B. Yurgelun (Harvard University)H-Index: 15
Last. Sonia S. Kupfer (U of C: University of Chicago)H-Index: 20
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#1A. James M. Daveson (UQ: University of Queensland)H-Index: 4
Last. S. WilsonH-Index: 1
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1 CitationsSource
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#1Benjamin D. McDonald (U of C: University of Chicago)H-Index: 8
#2Sonia S. Kupfer (U of C: University of Chicago)H-Index: 20
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#1Charles Muller (U of C: University of Chicago)H-Index: 2
#2Lindsay Matthews (UW: University of Wisconsin-Madison)
Last. Jennifer M. Weiss (UW: University of Wisconsin-Madison)H-Index: 13
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Purpose of review Identification of Lynch syndrome is important from an individual patient and public health standpoint. As paradigms for Lynch syndrome diagnosis have shifted in recent years, this review will discuss rationale and limitations for current strategies as well as provide an overview of future directions in the field.
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A number of inherited syndromes affect the gastrointestinal tract, including Lynch syndrome and other hereditary colorectal cancers, hereditary polyposis, hereditary gastric cancer, hereditary pancreatic cancer, and hereditary pancreatitis. Recognition and diagnosis of these syndromes are paramount because affected individuals and family members can be offered life-saving screening, risk-reducing surgeries, and other therapies. Genetic counseling and testing are critical components of risk asses...
#1Jamie M. Tjaden (NorthShore University HealthSystem)
#2Charles Muller (U of C: University of Chicago)H-Index: 2
Last. Joshua Melson (Rush University Medical Center)H-Index: 10
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