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Pedro Jorge Caldas Magalhães
Federal University of Ceará
EndocrinologyContraction (grammar)ChemistryAnesthesiaMedicine
116Publications
23H-index
1,381Citations
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Publications 115
Newest
Last. Jand Venes R. MedeirosH-Index: 18
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Anadenanthera colubrina var. cebil (Griseb.) Altschul (Fabaceae family), commonly known as the red angico tree, is a medicinal plant found throughout Brazil’s semi-arid area. In this study, a chemical analysis was performed to investigate the antidiarrheal activity and safety profile of red angico gum (RAG), a biopolymer extracted from the trunk exudate of A. colubrina. Upon FT-IR spectroscopy, RAG showed bands in the regions of 1608 cm−1, 1368 cm−1, and 1029 cm−1, which relate to the vibration ...
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#1Emanuella Feitosa de Carvalho (UFC: Federal University of Ceará)H-Index: 1
#2Kalinne Kelly Lima Gadelha (UFC: Federal University of Ceará)H-Index: 2
Last. Pedro Jorge Caldas Magalhães (UFC: Federal University of Ceará)H-Index: 23
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Neryl butyrate is a constituent of volatile oils obtained from aromatic plants. Aliphatic organic compound analogues chemically close to neryl butyrate possess vasodilator properties in rat aorta. To evaluate whether neryl butyrate has relaxing properties, this study tested its effects on isolated rat aorta. Unlike the analogues, neryl butyrate did not show relaxant profile in aortic rings precontracted with phenylephrine, but induced a contraction when it stimulated aortic rings under resting t...
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#1Thiago Brasileiro de Vasconcelos (UFC: Federal University of Ceará)H-Index: 3
Last. Pedro Jorge Caldas Magalhães (UFC: Federal University of Ceará)H-Index: 23
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#1Elizama Shirley Silveira (UFC: Federal University of Ceará)
#2Suzana B. Bezerra (UFC: Federal University of Ceará)H-Index: 2
Last. Luzia Kalyne Almeida Moreira Leal (UFC: Federal University of Ceará)H-Index: 20
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Abstract Arthur de Carvalho Drops® (ACD) is a traditional Brazilian herbal medicine used to treat functional gastrointestinal disorders (FGIDs). ACD is a formulation of herbal extracts from Matricaria recutita (chamomile), Foeniculum vulgare (fennel) and Gentiana lutea L. (gentian). Considering the popular use for FGIDs, the aim of this work was to investigate the ACD effect on gastric and intestinal parameters with emphasis in a mechanistic approach using isolated duodenal preparations of roden...
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#1Thayane Rebeca Alves-Santos (UFPE: Federal University of Pernambuco)H-Index: 1
#2Fabiano E. Xavier (UFPE: Federal University of Pernambuco)H-Index: 17
Last. Saad LahlouNote (UFC: Federal University of Ceará)H-Index: 23
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Abstract Mechanisms underlying the vasorelaxant effects of the synthetic nitro compound, trans-4-methoxy-β-nitrostyrene (T4MN) were studied in isolated small resistance arteries from spontaneously hypertensive rats (SHRs). T4MN caused vasorelaxation in endothelium-intact third-order branches of the mesenteric artery pre-contracted with noradrenaline (NA). This effect was unchanged by indomethacin and atropine but was significantly reduced by endothelium removal, L-NAME, LY294002, glybenclamide, ...
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#1Taylena Maria Teófilo (UFC: Federal University of Ceará)H-Index: 2
#2Gloria Pinto Duarte (UFPE: Federal University of Pernambuco)H-Index: 15
Last. Saad LahlouNote (UFC: Federal University of Ceará)H-Index: 23
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Abstract Previously, we showed that the synthetic nitroderivative trans-4-methyl-β-nitrostyrene (T4MeN) induced vasorelaxant effects in rat isolated aortic rings. Here, we investigated the mechanisms underlying the cardiovascular effects of T4MeN in normotensive rats. In pentobarbital-anesthetized rats, intravenous (i.v.) injection of T4MeN (0.03–0.5 mg/kg) induced a rapid (onset time of 1–2 s) and dose-dependent bradycardia and hypotension. These cardiovascular responses to T4MeN were abolished...
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#1Kalinne Kelly Lima Gadelha (UFC: Federal University of Ceará)H-Index: 2
#2Francisco José Batista-Lima (UFC: Federal University of Ceará)H-Index: 3
Last. Pedro Jorge Caldas Magalhães (UFC: Federal University of Ceará)H-Index: 23
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#1Francisco José Batista-Lima (UFC: Federal University of Ceará)H-Index: 3
#2Felipe Macário dos Santos Rodrigues (UFC: Federal University of Ceará)
Last. Pedro Jorge Caldas Magalhães (UFC: Federal University of Ceará)H-Index: 23
view all 9 authors...
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#1Thiago Brasileiro de Vasconcelos (UFC: Federal University of Ceará)H-Index: 3
Last. Pedro Jorge Caldas Magalhães (UFC: Federal University of Ceará)H-Index: 23
view all 6 authors...
VASCONCELOS, Thiago Brasileiro de et al. Vasodilator effects and putative guanylyl cyclase stimulation by 2-nitro-1-phenylethanone and 2-nitro-2-phenyl-propane-1,3-diol on rat aorta. European Journal of Pharmacology, Berlin, v. 830, p. 105-114, jul. 2018.
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