Mikael Cohen
University of Nice Sophia Antipolis
SurgeryPathologyPhysical therapyMultiple sclerosisMedicine
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Publications 98
BACKGROUND: Longitudinally extensive transverse myelitis (LETM) is classically related to aquaporin (AQP4)-antibodies (Ab) neuromyelitis optica spectrum disorders (NMOSD) or more recently to myelin oligodendrocyte glycoprotein (MOG)-Ab associated disease. However, some patients remain negative for any diagnosis, despite a large work-up including AQP4-Ab and MOG-Ab. Data about natural history, disability outcome, and treatment are limited in this group of patients. We aimed to (1) describe clinic...
#1Elisabeth MaillartH-Index: 9
#2Pierre Labauge (University of Montpellier)H-Index: 33
Last. A. Tourbah (Reims University)
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Background:Atypical myelitis in multiple sclerosis (MS) is characterized by extensive myelitis in the longitudinal (longitudinally extensive transverse myelitis) or axial plane (transverse myelitis...
Abstract Background : Eye movement abnormalities (EMA) are common in multiple sclerosis (MS). However, type and severity according to the MS stage are poorly known, especially in Radiologically Isolated Syndrome (RIS) and in Clinically Isolated Syndrome (CIS). Although MRI has been included in the MS diagnostic criteria, there may be clinical-radiological dissociation. Objective : To analyze by video-oculography (VOG) prevalence of EMA in different MS phenotypes and study correlations with brain...
#1Heloise JolyH-Index: 2
#2Mikael CohenH-Index: 10
Last. Christine Lebrun-FrenayH-Index: 17
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#1Alvaro Cobo-Calvo (French Institute of Health and Medical Research)H-Index: 2
#2Maria Sepúlveda (University of Barcelona)H-Index: 13
Last. Romain Marignier (French Institute of Health and Medical Research)H-Index: 29
view all 27 authors...
Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) are related to several acquired demyelinating syndromes in adults, but the therapeutic approach is currently unclear. We aimed to describe the response to different therapeutic strategies in adult patients with relapsing MOG-Ab-associated disease. This is a retrospective study conducted in France and Spain including 125 relapsing MOG-Ab patients aged ≥ 18 years. First, we performed a survival analysis to investigate the relapse risk between...
5 CitationsSource
#1M. LevrautH-Index: 1
#2Mikael CohenH-Index: 10
Last. Christine Lebrun-FrenayH-Index: 17
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Objective Meningeal involvement in Immunoglobulin G (IgG)-4-related disease is rare and only described in case reports and series. Because a review into the disease is lacking, we present 2 cases followed by a literature review of IgG4-related hypertrophic pachymeningitis (IgG4-HP). Methods Two IgG4-HP cases were reported, one involving the spinal cord and responding to surgical management and a second involving the brain and responding to Rituximab therapy. We then review clinical cases and cas...
#1Jonathan Ciron (University of Toulouse)H-Index: 7
#2Alvaro Cobo-Calvo (French Institute of Health and Medical Research)H-Index: 2
Last. Romain Marignier (French Institute of Health and Medical Research)H-Index: 29
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Objectives:We aim to (1) determine the frequency and distinctive features of short myelitis (SM) and longitudinally extensive transverse myelitis (LETM) in a cohort of adults with myelin oligodendr...
1 CitationsSource
#1Xavier Ayrignac (University of Montpellier)H-Index: 16
#2Valérie Rigau (University of Montpellier)H-Index: 25
Last. S. Kremer (UDS: University of Strasbourg)H-Index: 24
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Background The diagnosis of atypical inflammatory demyelinating lesions can be difficult. Brain biopsy is often required to exclude neoplasms. Moreover, the relationship between these lesions and multiple sclerosis and NMOSD is not clear.