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Luke A. Downey
Swinburne University of Technology
PsychiatryPsychologyCognitionEmotional intelligenceClinical psychology
117Publications
23H-index
1,808Citations
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Publications 116
Newest
#1Jin JiH-Index: 1
#2Matthew Flavel (La Trobe University)H-Index: 3
Last. Barry Kitchen (La Trobe University)H-Index: 2
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Abstract Evidence suggests that enhanced oxidative stress and mild, chronic inflammation is associated with the onset and progression of some neurological disorders. Hypothesis A polyphenol rich sugarcane extract may be active in protecting against this inflammation and neurological degeneration. Study design A series of cell culture strains and in vitro gene expression studies were used to understand the neuroprotective activity. Methods Extract was prepared according to a patented extraction p...
1 CitationsSource
#1Amie C. Hayley (Swinburne University of Technology)H-Index: 13
#2Maja GreenH-Index: 3
Last. Luke A. Downey (Swinburne University of Technology)H-Index: 23
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AbstractTo evaluate the sensitivity of the Securetec DrugWipe 6 S Ketamine device in detecting salivary ketamine, we administered three fixed, increasing sub-anaesthetic doses of intravenous ketami...
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#1Grace McPhee (Swinburne University of Technology)H-Index: 3
#2Luke A. Downey (Swinburne University of Technology)H-Index: 23
Last. Con Stough (Swinburne University of Technology)H-Index: 51
view all 3 authors...
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#1Luke A. Downey (Swinburne University of Technology)H-Index: 23
#2Tamara Simpson (Swinburne University of Technology)H-Index: 5
Last. Con Stough (Swinburne University of Technology)H-Index: 51
view all 8 authors...
B vitamins are essential for optimal brain and body function, and are particularly important for cortical metabolic processes that have downstream effects on mitigating oxidative stress. Oxidative stress has been linked to poor psychological outcomes including psychological distress, which has wide-reaching implications for the community and the workplace. Given work-related stress has been associated with poor mental health outcomes, high-dose B vitamin supplementation may be effective in impro...
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Study Objectives:Drowsiness leads to 20% of fatal road crashes, while inability to assess drowsiness has hampered drowsiness interventions. This study examined the accuracy of eye-blink parameters ...
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#1Amie C. Hayley (Swinburne University of Technology)H-Index: 13
#2Luke A. Downey (Swinburne University of Technology)H-Index: 23
Last. Yahya Shehabi (Monash University)H-Index: 24
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PURPOSE/BACKGROUND: As a sole agent, ketamine acutely compromises driving ability; however, performance after coadministration with the adjuvant sedating agents dexmedetomidine or fentanyl is unclear. METHODS/PROCEDURES: Using a randomized within-subject design, 39 participants (mean ± SD age, 28.4 ± 5.8 years) received 0.3 mg/kg bolus followed by 0.15 mg kg h infusion of ketamine (3-hour duration), in addition to either (i) 0.7 μg kg h infusion of dexmedetomidine for 1.5 hours (n = 19; KET/DEX)...
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#1Amie C. Hayley (Swinburne University of Technology)H-Index: 13
#2Maja Green (Monash University)H-Index: 3
Last. Yahya Shehabi (Monash University)H-Index: 24
view all 7 authors...
Abstract Analgesic doses of ketamine affects neurocognition; however, deficits under co-administration regimens are unknown. This study evaluated the effects of ketamine, alone and in combination with dexmedetomidine or fentanyl on neurocognition. Using a randomised, within-subjects gender stratified design, 39 participants (mean age = 28.4, SD ± 5.8) received a ketamine bolus of 0.3 mg/kg followed by 0.15 mg/kg/h infusion of ketamine (3 h duration). At 1.5 h post-ketamine infusion commencement,...
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#1Amie C. Hayley (Swinburne University of Technology)H-Index: 13
#2Carl L. Hart (Columbia University)H-Index: 40
Last. Luke A. Downey (Swinburne University of Technology)H-Index: 23
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BACKGROUND AND AIMS: Stimulant drug users have a greater prevalence of risky driving behaviour. This study aimed to assess how far this association remains after adjusting for aggressiveness. DESIGN: Cross-sectional interview study assessing associations between measures of risky driving behaviours as outcomes, measures of stimulant drug use as predictors and a measure of aggressiveness as a covariate. SETTING: United States. PARTICIPANTS: Data were drawn from wave 3 (2012-13) of the National Ep...
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#1Brook Shiferaw (Swinburne University of Technology)H-Index: 4
#2David P. Crewther (Swinburne University of Technology)H-Index: 29
Last. Luke A. Downey (Swinburne University of Technology)H-Index: 23
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Abstract Driving under the influence of alcohol is an ongoing cause of road traffic accidents. The biphasic nature of alcohol effects on subjective experience appears to contribute to the prevalence of drink-driving, as people perceive the declining phase of the BAC curve as recovery from intoxication and are more willing to drive despite significant impairments in objectively measured functions. The present study investigates whether alcohol-induced changes in gaze behaviour can be detected dur...
1 CitationsSource
#1Kat Droppert (Swinburne University of Technology)H-Index: 1
#2Luke A. Downey (Swinburne University of Technology)H-Index: 23
Last. Con Stough (Swinburne University of Technology)H-Index: 51
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Abstract Recent research is indicating predictive validity for emotional intelligence (EI) in a range of important scholastic variables including bullying, well-being and mental health. There have been some suggestions that emotional intelligence and resiliency in school children are also related, however, there is little research on these variables. Therefore, the present study attempted to bridge this gap by examining the relationship between EI, resiliency and scholastic performance. Specific...
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