Match!
Alan Reynolds
University of Glasgow
Physical therapyEcologyRheumatoid arthritisMedicineBiology
19Publications
8H-index
465Citations
What is this?
Publications 19
Newest
#1Eleanor K. O'Brien (UoB: University of Bristol)H-Index: 7
#2Megan Higgie (JCU: James Cook University)H-Index: 11
Last. Jon R. Bridle (UoB: University of Bristol)H-Index: 20
view all 5 authors...
Predicting how species will respond to the rapid climatic changes predicted this century is an urgent task. Species distribution models (SDMs) use the current relationship between environmental variation and species’ abundances to predict the effect of future environmental change on their distributions. However, two common assumptions of SDMs are likely to be violated in many cases: (i) that the relationship of environment with abundance or fitness is constant throughout a species’ range and wil...
12 CitationsSource
#1Eleanor K. O'Brien (University of Bath)H-Index: 7
#2Megan Higgie (JCU: James Cook University)H-Index: 11
Last. Jon R. Bridle (UoB: University of Bristol)H-Index: 20
view all 5 authors...
Predicting how species will respond to the rapid climatic changes predicted this century is an urgent task. Species Distribution Models (SDMs) use the current relationship between environmental variation and species' abundances to predict the effect of future environmental change on their distributions. However, two common assumptions of SDMs are likely to be violated in many cases: (1) That the relationship of environment with abundance or fitness is constant throughout a species' range and wil...
1 CitationsSource
#1Alan Reynolds (Glas.: University of Glasgow)H-Index: 8
#2Jan Lindström (Glas.: University of Glasgow)H-Index: 37
Last. Barbara K. Mable (Glas.: University of Glasgow)H-Index: 28
view all 4 authors...
Resistance to xenobiotics remains a pressing issue in parasite treatment and global agriculture. Multiple factors may affect the evolution of resistance, including interactions between life-history traits and the strength of selection imposed by different drug doses. We experimentally created replicate selection lines of free-living Caenorhabditis remanei exposed to Ivermectin at high and low doses to assess whether survivorship of lines selected in drug-treated environments increased, and if th...
2 CitationsSource
#1Tom C. Cameron (University of Essex)H-Index: 11
#2Daniel O'Sullivan (University of Leeds)H-Index: 21
Last. Tim G. Benton (University of Leeds)H-Index: 51
view all 6 authors...
The interaction between environmental variation and population dynamics is of major importance, particularly for managed and economically important species, and especially given contemporary changes in climate variability. Recent analyses of exploited animal populations contested whether exploitation or environmental variation has the greatest influence on the stability of population dynamics, with consequences for variation in yield and extinction risk. Theoretical studies however have shown th...
5 CitationsSource
#1Christian Bannister (Cardiff University)H-Index: 7
#2James Orr (Newcastle University)H-Index: 5
Last. Craig John Currie (Cardiff University)H-Index: 41
view all 8 authors...
Abstract Purpose Hepatic encephalopathy (HE) is a complication of cirrhosis signaling decompensation and is associated with mortality. There has been little characterization of HE once an incident episode has occurred and of what effect the transition to overt HE might have on outcomes. We characterized the relationships between the number of previous HE episodes and risk of subsequent episodes and mortality to better understand the natural history of HE. Methods Data on 321 patients from a 24-m...
6 CitationsSource
OBJECTIVES: The aim of this study was to calculate the marginal cost of dose escalation in people with rheumatoid arthritis treated with tumour necrosis factor (TNF) inhibitors across Europe. METHODS: The proportion of people who escalate their dose of TNF inhibitor and the average percentage increase in TNF inhibitor cost associated with escalators versus non-escalators was calculated from previously published estimates, weighted by the sample size for each study. The number of people with rheu...
#2Sara Jenkins-JonesH-Index: 17
Last. Craig John CurrieH-Index: 41
view all 6 authors...
2 CitationsSource
#1Christopher Llewellyn Morgan (Glas.: University of Glasgow)H-Index: 2
#2Paul Emery (Glas.: University of Glasgow)H-Index: 143
Last. Craig J. Currie (Glas.: University of Glasgow)H-Index: 1
view all 8 authors...
Objective. The objective of this study was to examine the long-term safety of etanercept (ETN) in comparison with conventional DMARDs in a large observational cohort of RA patients in the UK. Methods. Data were made available from the British Society of Rheumatology Biologics Register for a cohort of patients with RA treated with ETN and a reference cohort of RA patients treated with conventional DMARDs (maximum follow-up 10 years). The adjusted risk of events was compared using Cox proportional...
39 CitationsSource
#1Tom C. Cameron (Umeå University)H-Index: 11
#2Daniel O'Sullivan (University of Leeds)H-Index: 21
Last. Tim G. Benton (University of Leeds)H-Index: 51
view all 5 authors...
Source
#1Tom C. Cameron (Umeå University)H-Index: 11
#2Daniel O'Sullivan (University of Leeds)H-Index: 21
Last. Tim G. Benton (University of Leeds)H-Index: 51
view all 5 authors...
Understanding the consequences of environmental change on ecological and evolutionary dynamics is inherently problematic because of the complex interplay between them. Using invertebrates in microc ...
47 CitationsSource
12