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Sarah S. Cohen
University of North Carolina at Chapel Hill
116Publications
31H-index
2,627Citations
Publications 116
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#2Lee Harel-Sterling (U of T: University of Toronto)
Last.Ariane J. Marelli (MUHC: McGill University Health Centre)H-Index: 11
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To summarise existing heart failure (HF) risk prediction models and describe the risk factors for HF-related adverse outcomes in adult patients with congenital heart disease (CHD). We performed a systematic search of MEDLINE, EMBASE and Cochrane databases from January 1996 to December 2018. Studies were eligible if they developed multivariable models for risk prediction of decompensated HF in adult patients with CHD (ACHD), death in patients with ACHD-HF or both, or if they reported correspondin...
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#1Sarah S. CohenH-Index: 31
#2Michelle Gurvitz (Boston Children's Hospital)H-Index: 23
Last.Ariane J. Marelli (McGill University)H-Index: 32
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Abstract As life expectancy in patients with congenital heart disease (CHD) has improved, the risk for developing noncardiac morbidities is increasing in patients with adult CHD (ACHD). Among these noncardiac complications, malignancies significantly contribute to the disease burden of ACHD patients. Epidemiological studies of cancer risk in CHD patients are challenging because they require large numbers of patients, extended follow-up, detailed and validated clinical data, and appropriate refer...
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Background Outcome of patients with atrial septal defect (ASD) and severe pulmonary arterial hypertension (PAH) relates to right ventricular (RV) function. Magnetic resonance imaging (MRI) remains the gold standard for evaluating the RV function but it is not used routinely. We investigated the relationship between MRI and multiple echocardiography parameters, including the Right Ventricle End-Systolic Remodeling Index (RVESRI), a new prognostic marker in patients with PAH. Methods Twenty-three ...
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Abstract Background Cyanotic adults with congenital heart disease (ACHD) rely on life-sustaining adaptations to their chronic cyanosis and are at risk of adverse consequences if such adaptations are out of balance. They may benefit from surgical treatment options that were not available during their childhood. The “GUCH morbidity and mortality scores” were specifically designed to predict risks after surgery in ACHD and included comorbidities and patient age. We aim to assess their performance i...
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#1Bethany Hopkins (Nestlé)
#2Sarah S. CohenH-Index: 31
Last.Cathy Alberda (AHS: Alberta Health Services)H-Index: 9
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#1Amit S. Joshi (UNC: University of North Carolina at Chapel Hill)
#2Sarah S. Cohen (UNC: University of North Carolina at Chapel Hill)H-Index: 31
All eukaryotic cells contain membrane bound structures called organelles. Each organelle has specific composition and function. Some of the organelles are generated de novo in a cell. The endoplasmic reticulum (ER) is a major contributor of proteins and membranes for most of the organelles. In this mini review, we discuss de novo biogenesis of two such organelles, peroxisomes and lipid droplets (LDs), that are formed in the ER membrane. LDs and peroxisomes are highly conserved ubiquitously prese...
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#1John D. Boice (Vandy: Vanderbilt University)H-Index: 7
#2Sarah S. CohenH-Index: 31
Last.Elizabeth D. Ellis (ORAU: Oak Ridge Associated Universities)H-Index: 7
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AbstractPurpose: The study of low dose and low-dose rate exposure is of immeasurable value in understanding the possible range of health effects from prolonged exposures to radiation. The Million P...
4 CitationsSource
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#1Ashley P. Golden (ORAU: Oak Ridge Associated Universities)H-Index: 3
#2Elizabeth D. Ellis (ORAU: Oak Ridge Associated Universities)H-Index: 7
Last.John D. Boice (Vandy: Vanderbilt University)H-Index: 84
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AbstractPurpose: Mallinckrodt Chemical Works (MCW) was the earliest uranium processing facility in the United States, and in 1942 produced the uranium oxide used for the first sustained and controlled nuclear fission chain-reaction at the University of Chicago. A second follow-up through 2012 was conducted of 2514 White male workers employed 1942–1966 at the MCW for dose-response analyses for selected causes of death.Materials and methods: Organ/tissue-specific dose reconstruction included both ...
3 CitationsSource
#1John D. Boice (Vandy: Vanderbilt University)H-Index: 7
#2Elizabeth D. Ellis (ORAU: Oak Ridge Associated Universities)H-Index: 7
Last.Sarah S. CohenH-Index: 31
view all 6 authors...
AbstractBackground: The study of Japanese atomic bomb survivors, exposed briefly to radiation, finds the risk of radiation-induced lung cancer to be nearly three times greater for women than for men. Because protection standards for astronauts are based on individual lifetime risk projections, this sex-specific difference limits the time women can spend in space. Populations exposed to chronic or fractionated radiation were evaluated to learn whether similar differences exist when exposures occu...
3 CitationsSource
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