Laura H. Goldstein
King's College London
PsychiatryPsychologyPhysical therapyEpilepsyMedicine
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Publications 215
#1Laura H. GoldsteinH-Index: 46
#2Emily RobinsonH-Index: 8
Last. Paul McCrone ('KCL': King's College London)H-Index: 53
view all 17 authors...
BACKGROUND: We examined demographic, clinical, and psychological characteristics of a large cohort (n = 368) of adults with dissociative seizures (DS) recruited to the CODES randomised controlled trial (RCT) and explored differences associated with age at onset of DS, gender, and DS semiology. METHODS: Prior to randomisation within the CODES RCT, we collected demographic and clinical data on 368 participants. We assessed psychiatric comorbidity using the Mini-International Neuropsychiatric Inter...
OBJECTIVE: To characterize disease evolution in amyotrophic lateral sclerosis using an event-based model designed to extract temporal information from cross-sectional data. Conventional methods for understanding mechanisms of rapidly progressive neurodegenerative disorders are limited by the subjectivity inherent in the selection of a limited range of measurements, and the need to acquire longitudinal data. METHODS: The event-based model characterizes a disease as a series of events, each compri...
#1Laura H. GoldsteinH-Index: 46
#2Emily RobinsonH-Index: 8
Last. Mark P. RichardsonH-Index: 48
view all 17 authors...
Background Dissociative Seizures (DS) are paroxysmal events resembling epilepsy or syncope with characteristic features which allow separation from those and other medical conditions. This effectiveness study investigated whether cognitive behavioural therapy (CBT) plus standardised medical care (SMC) vs SMC-alone reduced DS occurrence. Methods We undertook a pragmatic, parallel arm, multi-centre randomised controlled trial (RCT). Potential participants were identified in neurology/epilepsy clin...
#1Susannah PickH-Index: 5
#2David G. Anderson (University of the Witwatersrand)H-Index: 4
Last. Timothy NicholsonH-Index: 17
view all 46 authors...
Objectives We aimed to identify existing outcome measures for functional neurological disorder (FND), to inform the development of recommendations and to guide future research on FND outcomes. Methods A systematic review was conducted to identify existing FND-specific outcome measures and the most common measurement domains and measures in previous treatment studies. Searches of Embase, MEDLINE and PsycINFO were conducted between January 1965 and June 2019. The findings were discussed during two...
#1Matthew Wilkinson (CCCU: Canterbury Christ Church University)
#2Elana Day ('KCL': King's College London)
Last. Laura H. Goldstein ('KCL': King's College London)H-Index: 46
view all 8 authors...
Abstract Objectives Little is known about the experiences of therapists delivering psychotherapy for patients with dissociative seizures (DS), a complex disorder associated with a range of comorbid psychosocial and mental health difficulties. This study set out to explore therapists' experiences of delivering DS-specific, manualized cognitive behavioral therapy (CBT) to adults with DS within the context of a randomized control trial. Methods Interviews were conducted with 12 therapists involved ...
#1Timothy Nicholson (St George's, University of London)H-Index: 17
#2Alan Carson (St George's, University of London)H-Index: 2
Last. Jon Stone (St George's, University of London)H-Index: 2
view all 11 authors...
The development and selection of optimal outcome measures is increasingly recognized as a key component of evidence-based medicine, particularly the need for the development of a standardized set o...
2 CitationsSource
#1Jon Stone (Edin.: University of Edinburgh)H-Index: 61
#2Hannah Callaghan (Edin.: University of Edinburgh)H-Index: 1
Last. Laura H. Goldstein ('KCL': King's College London)H-Index: 46
view all 8 authors...
Abstract Purpose Patients with dissociative (non-epileptic) seizures typically receive their diagnosis from neurologists, but are often referred to psychiatrists, whom they may be reluctant to go and see. We aimed to assess which factors were associated with first attendance at psychiatric services. Methods A cohort study of 698 participants involved in the pre-randomisation phase of the CODES trial, a randomised controlled trial assessing the benefit of cognitive behavioural therapy for dissoci...
1 CitationsSource
#1Glenn Nielsen (St George's, University of London)H-Index: 1
#2Jon Stone (RIE: Edinburgh Royal Infirmary)H-Index: 61
Last. Mark J. Edwards (St George's, University of London)H-Index: 44
view all 12 authors...
Background Patients with functional motor disorder (FMD) experience persistent and disabling neurological symptoms such as weakness, tremor, dystonia and disordered gait. Physiotherapy is usually considered an important part of treatment; however, sufficiently-powered controlled studies are lacking. Here we present the protocol of a randomised controlled trial (RCT) that aims to evaluate the clinical and cost effectiveness of a specialist physiotherapy programme for FMD.
#1Laura H. Goldstein ('KCL': King's College London)H-Index: 46
#2Emily Robinson ('KCL': King's College London)H-Index: 8
Last. Jon Stone (Edin.: University of Edinburgh)H-Index: 61
view all 18 authors...
Objective: We aimed to characterise the demographics of adults with dissociative (non-epileptic) seizures, placing emphasis on distribution of age at onset, male:female ratio, levels of deprivation and dissociative seizure semiology. Methods: We collected demographic and clinical data from 698 adults with dissociative seizures recruited to the screening phase of the CODES Trial, from 27 neurology/specialist epilepsy clinics in the United Kingdom. We described the cohort in terms of age, age at o...
2 CitationsSource
#1Kirsty R. Weeks (UCL: University College London)
#2Rebecca L. Gould (UCL: University College London)H-Index: 13
Last. Vanessa Lawrence ('KCL': King's College London)H-Index: 14
view all 16 authors...
AbstractBackground: There is a lack of knowledge about what factors may impede or facilitate engagement in psychological interventions in people with motor neuron disease (pwMND) and how such inter...