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Ana-Marija Domijan
University of Zagreb
167Publications
25H-index
1,606Citations
Publications 180
Newest
Abstract Imatinib mesylate (IM) is the first developed protein kinase inhibitor and recently it has topped consumption rates among targeted and total anticancer drugs. Although there are indications that IM possesses cyto/genotoxic activities against normal non-target cells as well, there is a lack of information regarding the underlying mechanism involved in those actions. Therefore, we aimed to evaluate the response of human circulating blood cells towards oxidative stress after IM treatment (...
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#1Ivan OžvaldH-Index: 1
Last.Mirta MilićH-Index: 15
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#1Ivan OžvaldH-Index: 1
Last.Mirta MilićH-Index: 15
view all 6 authors...
#2Marko GerićH-Index: 10
Last.Jadranka FreceH-Index: 12
view all 9 authors...
AbstractAn adequate level of low molecular weight thiols (LMW-SH, especially glutathione (GSH)) protects cellular macromolecules against toxic agents, and is used as a sensitive biomarker of exposu...
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#1Renata BibaH-Index: 2
#2Petra CvjetkoH-Index: 13
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#1Ana-Marija DomijanH-Index: 25
#2Renata BibaH-Index: 2
Last.Biljana BalenH-Index: 13
view all 6 authors...
#1Renata BibaH-Index: 2
#2Petra CvjetkoH-Index: 13
Last.Biljana BalenH-Index: 13
view all 9 authors...
Abstract Sodium copper chlorophyllin (CHL) is a food colorant that exhibits many beneficial properties, including potential for use in radiotherapy. Nevertheless, genotoxicity studies investigating radioprotective properties against γ-radiation on human cells are rather scarce. The aim of this study was to assess the cytotoxicity, genotoxicity and induction of malondialdehyde formation on CHL pre-treated whole blood cells after an absorbed dose of 5 Gy γ-radiation. Irradiated whole blood cells p...
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