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Yoshihiko Nishio
Kagoshima University
EndocrinologyInsulinDiabetes mellitusMedicineBiology
153Publications
37H-index
4,614Citations
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Publications 113
Newest
#1Keiko KondoH-Index: 9
#2Katsutaro MorinoH-Index: 26
Last. Hiroshi MaegawaH-Index: 48
view all 16 authors...
14 CitationsSource
#1Kohji Nagayama (Shiga University of Medical Science)H-Index: 1
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 15 authors...
N-3 polyunsaturated fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have protective effects against atherosclerosis. Monocyte chemotactic protein (MCP)-1 is a major inflammatory mediator in the progression of atherosclerosis. However, little is known about the regulation of MCP-1 by DHA and EPA in vessels and vascular smooth muscle cells (VSMCs). In this study, we compared the effect of DHA and EPA on the expression of Mcp-1 in rat arterial strips and rat VSMCs. DH...
5 CitationsSource
#1Tomoaki Higashiyama (Shiga University of Medical Science)H-Index: 6
#2Yasuhiro Nishida (Shiga University of Medical Science)H-Index: 16
Last. Masahito Ohji (Shiga University of Medical Science)H-Index: 33
view all 7 authors...
Purpose To quantitatively evaluate the efficacy of methylprednisolone pulse therapy for extraocular muscle inflammation in thyroid-associated ophthalmopathy (TAO) using the short-tau inversion-recovery (STIR) technique of magnetic resonance imaging (MRI).
6 CitationsSource
Source
#1Shinji Kume (Shiga University of Medical Science)H-Index: 30
#2Takashi Uzu (Shiga University of Medical Science)H-Index: 38
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 14 authors...
Anti-diabetic agent-related hypoglycemia is a serious complication in type 2 diabetic patients on hemodialysis. Therefore, we assessed the efficacy and tolerability of 24 weeks of monotherapy with vildagliptin, a dipeptidyl peptidase four inhibitor, which is a new class of antidiabetic agent. This open-label, single-arm clinical trial was performed on 26 patients on hemodialysis. The primary assessments were changes in postprandial glucose level and glycated albumin (GA). During the study, three...
10 CitationsSource
#1Keiko Nakao (Shiga University of Medical Science)H-Index: 5
#2Takashi Uzu (Shiga University of Medical Science)H-Index: 38
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 13 authors...
Aims/Introduction: Although increases in urinary protein excretion generally precede a decline in the glomerular filtration rate, non-proteinuric renal impairment is common in patients with diabetes. In the present study, we examined the relationship between indices of arterial stiffness and renal function in type 2 diabetic patients without proteinuria. Methods: Blood sampling, 24-h urine collection, brachial–ankle pulse wave velocity, and 24-h ambulatory blood pressure monitoring were performe...
2 CitationsSource
#1Tomoaki Higashiyama (Shiga University of Medical Science)H-Index: 6
#2Yasuhiro Nishida (Shiga University of Medical Science)H-Index: 16
Last. Masahito Ohji (Shiga University of Medical Science)H-Index: 33
view all 6 authors...
18 CitationsSource
#1Akiko Yagi (Shiga University of Medical Science)H-Index: 1
#2Yoshihiko Nishio (Shiga University of Medical Science)H-Index: 37
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 10 authors...
The importance of sleep disturbance and depression in patients with type 2 diabetes is unclear. Our objective was to evaluate their effects on the quality of life (QOL) of patients with type 2 diabetes. For the study, 270 patients were recruited from the Shiga Prospective Observational Follow-up Study for Diabetic Complications. Depressive symptoms, sleep disturbance, and QOL were assessed by use of the Zung Self-Rating Depression Scale (SDS), the Pittsburgh Sleep Quality Index (PSQI), and SF-8,...
1 CitationsSource
#1Motoyuki Kondo (Shiga University of Medical Science)H-Index: 9
#2Satoshi UgiH-Index: 26
Last. Hiroshi MaegawaH-Index: 48
view all 10 authors...
Abnormal secretion of adipocytokines promotes atherosclerosis, diabetes and insulin resistance, and is mainly induced by adipocyte hypertrophy. Recently, the circulating adipocytokine concentrations were reported to change in the postprandial period, as the levels of TNFα, IL-6 IL-8 and MCP-1 increased after a meal, whereas that of adiponectin decreased. These data suggest that prandial modulation of cytokines may be involved in the pathogenesis of atherosclerosis in type 2 diabetes. However, th...
5 CitationsSource
#1Satoshi Ugi (Shiga University of Medical Science)H-Index: 26
#2Hiroshi Yamamoto (Shiga University of Medical Science)H-Index: 23
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 11 authors...
Objective To examine the effect of laparoscopic sleeve gastrectomy (LSG) on glucose metabolism.
5 CitationsSource
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